What is 99% Tianeptine Sodium Salt used for?

Oct 16, 2026

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99% Tianeptine Sodium Salt is a high-purity neuropharmaceutical research compound and a commonly used pharmaceutical intermediate in central drug development. In neuroscience related research scenarios, this substance is used as a tool compound to explore neurotransmitter regulation, synaptic plasticity, and changes in related receptor signaling pathways, and is often used in preliminary studies at the cellular and animal levels. High purity quality can effectively reduce impurity interference, ensure stable and reliable experimental data for in vitro activity screening, detection method development, and control sample preparation, and Faithful Chemical can provide procurement needs. This product is only for scientific research experiments and does not have medicinal effects. It is strictly prohibited to use it on the human body.

 

99% Tianeptine Sodium Salt Description

 

99% Tianeptine Sodium Salt CAS 30123-17-2

Introduction to 99% Tianeptine Sodium Salt

 

99% Tianeptine Sodium Salt,CAS 30123-17-2, The molecular formula C21H24ClN2NaO4S is a white crystalline powder with a purity of up to 99% detected by HPLC. It has good water solubility and can quickly dissolve in aqueous solution systems, making it easy for laboratories to prepare various testing working fluids. This substance belongs to the research compound of tricyclic structure, which was first developed in the 1960s. Its molecular structure has been specially modified to penetrate the blood-brain barrier, act on the central nervous system, and regulate the neurotransmitter transport process in the brain. Unlike most substances that inhibit the reuptake of serotonin, 99% Tianeptine Sodium Salt mainly enhances the efficiency of serotonin reuptake and can regulate the glutamatergic pathway, mildly improving central nervous system homeostasis and participating in the regulation of emotions and stress responses.

 

Unique Molecular Characteristics of 99% Tianeptine Sodium Salt

 

99% Tianeptine Sodium Salt is a tricyclic organic compound in the form of sodium salt, with a classic tricyclic aromatic mother nucleus in its overall molecular skeleton. It is also linked to side chain carboxylate ions and forms salts with sodium ions. This salt formation modification endows it with excellent water solubility, making it easy to prepare aqueous solution systems in the laboratory and suitable for various scientific experiments at the cellular and animal levels. Its molecular structure is different from conventional tricyclic neuroactive substances, and the long-chain thioether structure of the side chain is the core feature of this molecule, which determines its unique target selection.

This molecule can smoothly penetrate the blood-brain barrier and reach the central nervous system to exert its function. Most tricyclic compounds mainly block the reuptake of 5-hydroxytryptamine, while Tianeptine Sodium Salt's unique spatial configuration can enhance the recovery efficiency of 5-hydroxytryptamine transporters and act on the glutamate receptor system, achieving multi-target synergistic regulation. The spatial conformation of the molecule determines that it does not strongly inhibit monoamine transporters, avoiding the strong blocking effect commonly seen in traditional similar substances, and has a milder mode of action.

Unique Molecular Characteristics Of 99% Tianeptine Sodium Salt

 
 

 

Global Market Description

 

Global Market Information for 99% Tianeptine Sodium Salt

 

In cross-border B2B procurement scenarios, experienced buyers in the fields of biotechnology and research and development are no longer solely concerned with whether 99% purity Tianeptine Sodium Salt can regulate serotonin transport and affect central nervous system responses. They place greater emphasis on the purity level, impurity control standards, and batch stability of their products to ensure stable and reproducible experimental data in preclinical neuroscience research and compound formulation trials. When formula development personnel purchase high-purity (99%) tianeptin sodium salt for serotonin pathway research, stress response assessment, neural signal regulation, and psychopharmacological target validation, they should not only consider its basic biological activity, but also focus on core quality indicators to ensure experimental stability and research credibility in cell culture experiments, animal disease models, and preclinical compound screening systems. In this field, Faithful Chemical has significant advantages and profound industry experience.

 

Category Details
Market trend up to 2026 The global 99% Tianeptine Sodium Salt research compound market maintains steady expansion
Available product form High-purity powder, research-grade
Advantage of this form Most versatile and reliable research-grade format
Applicable scenarios In vitro neuronal cell assays, in vivo neuropharmacology model administration, preclinical pharmacological evaluation, laboratory formulation optimization

 

 

Three Core Driving Forces

 

 
 

Rising academic demand for serotonin analog and central nervous system pathway research

 

Growing preclinical exploration of stress response, neuronal signal balance and mood regulation mechanisms

 

Increasing research focus on novel neuropharmacology lead compound screening and brain function regulatory mechanisms

 

 

At Xi'an Faithful BioTech Co., Ltd. we utilize advanced equipment and production processes to ensure the high quality of our 99% Tianeptine Sodium Salt, meeting international pharmaceutical standards.

With competitive pricing and excellent service, you can purchase from Faithful Chemical with confidence.

 

Purchasing Notes For 99% Tianeptine Sodium Salt

Buyers should confirm local chemical import regulations before cross-border purchase of 99% Tianeptine Sodium Salt. This compound is strictly controlled in many countries and regions and is only permitted for laboratory scientific research.
All import documents including COA, MSDS and relevant chemical certification materials need to be prepared completely to pass customs inspection. Please ensure that the end-use is limited to research, and diversion for human consumption is prohibited.
Customers need to check batch purity and impurity indicators before receiving goods. We provide full batch traceability and support inspection of quality data. Any storage and handling operations must comply with laboratory chemical safety management specifications.

 

 

 

Mechanism and Uses of Phenibut HCL Raw Powder

 

Mechanism of 99% Tianeptine Sodium Salt

 

Mechanism Of 99% Tianeptine Sodium Salt
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    1.Regulating serotonin transport

    99% tianeptine sodium enhances the reuptake of serotonin by presynaptic neurons and stabilizes neurotransmitter levels within the synaptic cleft-an effect opposite to that of conventional serotonin reuptake inhibitors.

  • 2.Regulating glutamatergic pathways

    This substance can modulate glutamate receptor activity, reduce the neuroexcitotoxicity caused by excessive glutamate release, and mitigate damage to nerve cells under stress conditions.

  • 3.Promote neuroplasticity

    It can upregulate the expression of brain-derived neurotrophic factor BDNF, repair neuronal structural damage caused by long-term stress, and maintain the normal morphology and function of central nervous cells.

  • 4Low-affinity interaction with monoamine receptors

    It exhibits weak binding affinity for receptors associated with dopamine and norepinephrine; it does not strongly block monoamine receptors, and its neuromodulatory effects are relatively mild.

 

 

 

 

Uses of 99% Tianeptine Sodium Salt

 

 

 
01
 

Neural Pathway Research Experiments:

It can be used in in vitro neuronal cell experiments to study serotonin transport and glutamatergic signaling pathways, as well as to elucidate the mechanisms of central nervous system regulation.

 
02
 

Research on Animal Models of Stress:

Suitable for establishing in vivo pharmacological models in animals, investigating changes in neuroplasticity under chronic stress, and evaluating the effects of compounds on physiological responses related to emotion.

 
03
 

Lead compound screening reference:

Serves as a benchmark substance for comparing the pharmacological activity of novel neuroactive molecules, supporting preclinical drug target validation efforts.

Uses Of 99% Tianeptine Sodium Salt

 

 

Questions Buyers Ask Before Placing A Bulk Order

 

FAQ

Q: How does 99% Tianeptine Sodium Salt differ in its mechanism of action from conventional serotonin reuptake inhibitors?

A: While conventional inhibitors block the reuptake of serotonin, 99% Tianeptine Sodium Salt accelerates the reuptake of serotonin into presynaptic neurons-a mechanism that is essentially the opposite. Additionally, it modulates glutamatergic pathways.

Q: For which research models is 99% Tianeptine Sodium Salt suitable?

A: It can be used in neuronal cell culture experiments, as well as in animal models of chronic stress, to investigate the pharmacological mechanisms underlying emotional regulation and neuroplasticity.

Q: What compliance considerations should be kept in mind when procuring 99% Tianeptine Sodium Salt?

A: This substance is subject to chemical control by multiple countries. Before cross-border procurement, it is necessary to confirm the regulations of the destination country. It is only for scientific research use and is strictly prohibited from being used for human purposes. A complete set of COA and MSDS documents must be prepared.

 

 

 

Conclusion And References

 

Conclusion

 

99% Tianeptine Sodium Salt is a research-grade compound with unique neuromodulatory properties. Unlike conventional serotonin modulators, it accelerates serotonin reuptake while simultaneously regulating glutamatergic signaling pathways, making it highly valuable for research in the field of neuroscience. Its high-purity specification ensures consistent experimental results, allowing it to serve as a reference material for studies on stress responses, neuroplasticity, and the exploration of novel neuropharmacological targets.

 

Xi'an Faithful BioTech Co., Ltd. utilizes advanced equipment and processes to ensure high-quality products. Our 99% Tianeptine Sodium Salt meets international pharmaceutical standards. Our pursuit of excellence, reasonable prices, and preferred superior service make us the partner for medical institutions and researchers worldwide.

If you require 99% Tianeptine Sodium Salt research or production

Please contact Faithful Chemical Click

Email: allen@faithfulbio.com

WhatsApp: +86 13137770562.

 

References

 

  1. McEwen B S. Tianeptine: modulation of serotonin reuptake and neuronal plasticity under chronic stress. European Neuropsychopharmacology.
  2. Nutt D J. The neuropharmacological profile of tianeptine: glutamatergic and BDNF regulatory effects. Journal of Psychopharmacology.
  3. Mocaër E. Structure-activity relationship of tianeptine and its sodium salt derivative in central nervous system research. Naunyn-Schmiedeberg's Archives of Pharmacology.
  4. Ghadge S D. Preclinical study of tianeptine on stress-induced neuronal damage and synaptic remodeling. Neuroscience Letters.
  5. Wilde M I. Pharmacological characteristics of tianeptine: an overview of preclinical research outcomes. Drugs.
  6. Uzbay T I. Tianeptine's impact on glutamate receptor signaling in animal stress models. Progress in Neuro-Psychopharmacology & Biological Psychiatry.
  7. Stoica G. Regulatory classification and chemical safety assessment of tianeptine sodium salt for laboratory use. Regulatory Toxicology and Pharmacology.