Melatonine is a hormone secreted by the pineal body of the pituitary gland in the body. The degree of secretion of this hormone is negatively correlated with light. Pure Melatonin powder is a white or off white crystalline powder, which is an essential natural hormone in the body. Research has shown that as one ages, the secretion of melatonin decreases, and in old age, new melatonin is no longer secreted. Therefore, early intake and supplementation of sufficient melatonin can completely improve the function of the endocrine system, delay the speed of body aging and organ degeneration.
| Molecular formula |
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Item |
Standard |
Test Results |
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Appearance |
White to off-white crystalline powder |
Conform |
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Identification |
IR,UR,HPLC should conform |
Conform |
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Solubility |
Soluble in acetone, ethyl acetate & in methanol; Slightly soluble in water |
Conform |
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Loss on drying |
≤1.0% |
0.09% |
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Residue on ignition |
≤0.1% |
0.04% |
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Heavy metals |
≤20ppm |
<20ppm |
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Chloride & Sulfate |
≤0.02% |
Conform |
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Related substances |
Any single impurity≤0.1% |
0.058% |
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Total impurities≤1.0% |
0.48% |
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Assay |
98.5~101.5%(on dried basis) |
98.83% |
Is exogenous supplementation of melatonin safe?
Melatonin belongs to the indole heterocyclic compound, and its chemical name is N-ACETYL-5-METHOXYTRYPTAMINE. Normally, after the synthesis of melatonin powder in the human body, this product is stored in the pineal gland, and then the sympathetic nervous system controls pineal gland cells to release suitable melatonin to adapt to changes in the body. According to research findings, the secretion of melatonin has a clear circadian rhythm, with suppressed secretion during the day and active secretion at night. Therefore, staying up late, especially using a computer or mobile phone before bedtime, may seriously affect melatonin levels. According to relevant data, if electronic products with backlit displays are used for only 2 hours before bedtime, melatonin can be suppressed by 22%, leading to sleep problems such as inability to sleep deeply, frequent dreaming, and being easily interrupted. In addition, although most people's endogenous melatonin can meet their physiological needs, elderly people or those who may lack the ability to produce appropriate melatonin naturally, choosing exogenous melatonin supplementation is a relatively safe strategy.
What are the applications of melatonin?
Melatonin powder is highly conserved, but it helps prevent ischemia-reperfusion injury in the liver, brain, myocardium, intestines, and kidneys. Moreover, pure melatonin is a non receptor free radical scavenger and broad-spectrum antioxidant. Due to its outstanding functions, it is widely used in medical and health products that can enhance the immune function of the human body.
① The effect on the brain: Melatonin absorbed by the brain is concentrated in the midbrain and hypothalamus. Moderate intake can enhance the activity of brain pyridoxal kinase, thereby promoting the decarboxylation of glutamate to form gamma aminobutyric acid and L-5-Hydroxytryptophan decarboxylates to form Serotonin hydrochloride. The increase in the content of these two inhibitory neurotransmitters has a regulatory and sedative effect on the central nervous system.
② Effects on the hypothalamus and pituitary gland: Polypeptides produced by the pineal gland can reduce gonadotropins (GnRH) (FSH, LH) and melanocyte stimulating hormone (MSH), while increasing growth hormone (GH). If only exogenous melatonin is used, the same effect can be achieved.
③ The relationship with the gonads: Pinecone hormone has an inhibitory effect on the reproductive system, and environmental light and sympathetic nervous system can affect reproductive system function by controlling the synthesis and release of melatonin in the pineal gland.
④ Relationship with thyroid gland: This product can inhibit thyroid function by suppressing hypothalamic TRH release and pituitary thyroid stimulating hormone (TSH) secretion.
⑤ Relationship with the adrenal cortex: Melatonin has a strong inhibitory effect on the adrenal cortex, leading to reduced secretion of aldosterone and decreased excretion of 17 ketosteroids.
⑥ The relationship with pancreatic islets: Pine nuts can lead to a decrease in blood sugar and an increase in glucose tolerance.
In summary, the pineal gland can assist the pituitary gland in regulating endocrine function, maintaining a relatively constant internal environment and controlling certain endocrine functions, especially playing an important role in the gonads.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Melatonine powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
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