Praziquantel Powder CAS 55268-74-1
Product Name:Praziquantel powder
CAS NO.:55268-74-1
Molecular Formula:C19H24N2O2
EINECS.NO:259-559-6
Synonym:Praziquantel;Azinox;biltricide;Cesol;Cysticide;Distocide;droncit;embay8440;Prazinon;pyquiton
Lead Time:1-3 days
Shipping:DHL,Germany DHL,Germany DPD,UPS,USPS,FedEx,EMS,By Air,By Sea etc
Store & Shelf life:Cool & dry place;36 months
Other:There are warehouses in the United States, Australia and Germany
Description
what is Praziquantel powder?
Praziquantel powder is a broad-spectrum anthelmintic synthetic drug discovered abroad in the 1970s. After it was reported to be effective against schistosomiasis in 1977, it was trial produced domestically in the same year and confirmed to have significant therapeutic effects on schistosomiasis in Japan. This product is a colorless crystalline powder, odorless and slightly bitter, and is stable under normal conditions. The histological observation results of in vivo and in vitro experiments showed that after the action of this drug, the glycogen of the parasite was significantly reduced, and the ribonucleic acid and alkaline phosphatase were also decreased. However, the activity of alkaline protein reaction or acid phosphatase increased.
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Product name |
Praziquantel |
|
CAS |
55268-74-1 |
|
|
Molecular formula |
C19H24N2O2 | |
|
Molecular weight |
312.41 | |
| EINECS | 259-559-6 | |
|
Appearance |
white powder |
|
|
Melting point |
136-138°C (dec.) | |
| Storage | -20°C, Inert atmosphere | |
| Density |
1.1209(roughestimate) |
What are the use of Praziquantel powder?
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Praziquantel powder is a broad-spectrum antiparasitic drug that is effective against Schistosoma japonicum, Schistosoma mansoni, Schistosoma Egyptian, Clonorchis sinensis, Paragonimus, Fasciola, Taenia solium, and cysticercosis. Especially with a strong killing effect on tapeworms, it is currently the most effective medication for schistosomiasis If you need it, pls click e-mail sales1@faithfulbio.com |
what is the mechanism of Praziquantel powder ?
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Insecticidal mechanism of Praziquantel powder, at the molecular level, is that Praziquantel rapidly disrupts the Ca2+balance in the insect body, causing excitement and muscle contraction of the insect body, preventing the parasitic schistosomiasis in the portal vein system from adsorbing to the blood vessel wall and being carried into the liver by blood flow (liver migration), thereby causing damage; The second is that it causes damage to the syncytial cortex of schistosomiasis, which not only affects the absorption, excretion, and secretion functions of the parasite, leading to disturbances in sugar metabolism, enzyme systems, etc., but also exposes the antigenic determinants on the parasite's surface, allowing the host's immune system to recognize them and attract a large number of inflammatory cells such as neutrophils, eosinophils, macrophages, etc. to gather around the parasite for attack. |
Product Specification
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Items |
Specifications |
Results |
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Appearance |
White or practically white crystalline powder |
Conforms |
|
Solubility |
Very slightly soluble in water, freely soluble in alcohol and chloroform |
Conforms |
|
Identification |
IR |
Conforms |
|
Melting point |
136~142℃ |
138.7~140.3℃ |
|
Heavy metals |
≤0.002% |
Conforms |
|
Loss on drying |
≤0.5% |
0.2% |
|
Phosphate |
≤0.05% |
Conforms |
|
Residue on ignition |
≤0.1% |
Conforms |
|
Impurity A ≤0.2% |
0.03% |
|
|
Related compounds |
Impurity B ≤0.2% |
0.06% |
|
Impurity C ≤0.2% |
0.02% |
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|
Assay |
98.5%~101.0% |
99.4% |
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Dichloromethane: ≤600ppm |
ND |
|
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Residue solvent |
Ethyl acetate: ≤5000ppm |
Conforms |
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Ethanol: ≤5000ppm |
Conforms |
Conclusion：Conform with specification and qualified.
What are the side effects of Praziquantel Powder?
1. One hour after the first use of Praziquantel powder, dizziness, headache, nausea, abdominal pain, diarrhea, fatigue, limb soreness, etc. may occur, which are generally mild in severity, have a short duration, do not affect treatment, and do not require treatment.
2. A small number of cases present with symptoms such as palpitations and chest tightness. The electrocardiogram shows changes in T waves and out of phase contractions, occasionally accompanied by supraventricular tachycardia and atrial fibrillation.
3. A small number of cases may present with transient elevation of transaminase and toxic hepatitis.
4. Occasionally, it can induce mental disorders or gastrointestinal bleeding.
5. Hernia, allergic reactions (rash, asthma), etc. can also be seen
How and where to buy Praziquantel Powder?
We have 8 years of experience in selling legal scientific research drugs and have a good reputation, making us a trustworthy partner.
We ensure the quality of our products through independent experimental testing, and every customer is our VIP.
Send your Inquiry for more information, Click email：sales1@faithfulbio.comNow.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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Note: The product is for research use only and is not intended for diagnosis, treatment, disease prevention, etc.
Send your Inquiry for more details, Click email：sales1@faithfulbio.com Now.
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