Introduction to 5 amino 1mq：
5 amino 1mq is an effective inhibitor of nicotinamide N-methyltransferase (NNMT) (IC50=1.2 μM), which can selectively bind to the substrate binding site residues of NNMT. 5 amino 1mq can promote the differentiation of myoblasts in vitro and enhance the fusion and regeneration ability of muscle stem cells in aged mice.
CASNo.: 42464-96-0
Melting point: 213-214 C.
Storage conditions: Store at-20 C.
Solubility: soluble in dimethyl sulfoxide.
Color: Brown to reddish brown powder
What is 5 amino 1mq?
5 Amino 1mq powder is a small molecule drug whose function is to block the activity of an enzyme called NNMT. NNMT plays an important role in metabolism and energy, and is mainly active in adipose tissue. By blocking NNMT, 5 Amino 1mq can stimulate the increase of nicotinamide adenine dinucleotide (NAD+), and nicotinamide adenine dinucleotide (NAD+) is the core cofactor of cell metabolism, thus increasing metabolic rate and activating a gene named sirtuin-1 (SIRT1). SIRT1 is also called "longevity gene" because it plays a role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular diseases, kidney diseases, liver diseases, neurodegenerative diseases and cancer.
This means that 5 Amino 1mq allows your body to burn fat for energy while giving priority to maintaining muscle mass. 5 Amino 1mq can safely and effectively reverse and prevent obesity caused by diet. This is a potentially superior treatment option for patients with type II diabetes and other metabolic complications of obesity. In addition, the increase of NAD+ can activate SIRT1, which indicates that 5 Amino 1mq is expected to develop comprehensively.
Ideal for patients with anti-aging programs.
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Product Specification
| Item | Specification | Results |
| Appearance | Yellow powder to pink powder | Complies |
| Purity(HNMR) | 99.0% min | Complies |
| Purity(HPLC) | 99.0% min | 99.20% |
| 400MHz 1H | Consistent | Complies |
| MS | 159.2±1.0 | 158.2 |
| Conclusion: Conform with USP Standard | ||
Synthesis method of 5 Amino 1mq
Step 1: Add 50mL 95％ 95% ethanol and 4.35 g (0.025 mol) of 5- nitroquinoline into a 100mL three-necked bottle equipped with a thermometer and a mechanical stirrer, add 0.50 g of 10% PD/C and 2.65 g (0.045 mol) of 80% hydrazine hydrate while stirring, heat and reflux for 3 hours, filter while the reaction is finished, and evaporate the filtrate.
Step 2: add methyl iodide (0.160ml, 0.365g, 2.6mmol) into tetrahydrofuran (7ml) solution of 5- aminoquinoline (0.277g, 1.9mmol), and stir for 1 day at room temperature until a red solid is precipitated. After filtration, the filter cake was washed with tetrahydrofuran (2×5ml) and dried in vacuum to obtain 0.240g of compound 5- amino -1- methylquinoline -1- onium iodide. Evaporating the filtrate, dissolving the residue in tetrahydrofuran (4ml), adding 0.090ml of methyl iodide, and stirring at room temperature for 1 day. The product was filtered off, washed with THF and dried to obtain 0.228g of 5 Amino 1mq with an overall yield of 86%.
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Analysis of the role of 5 Amino 1mq
5 Amino 1mq plays an important role in metabolism by participating in the methylation of nicotinamide in vitamin B3 and affecting the metabolism of adipocytes. Its activity is related to the control of fat storage, energy balance and even the aging process of cells.
What role can 5 Amino 1mq play?
5 Amino 1mq powder basically interferes with the normal function of enzymes by inhibiting NNMT, which will lead to many beneficial metabolic changes for those who want to improve their overall health and physique. This inhibition can make metabolism more active, thus reducing fat storage, promoting the conversion of fat into energy, and possibly slowing down the cell aging process.
What are the advantages of 5 Amino 1mq?
Excellent bodybuilding potential
5 Amino 1mq has become a popular choice for bodybuilders and fitness enthusiasts because of its unique mechanism. It can change the energy consumption of the body to burn fat and possibly increase muscle mass. In addition to helping to shape a slimmer figure, this change also provides great benefits for strengthening strength and gaining muscle lines. It can also improve muscle quality and endurance.
Slow down the aging of cells
Although aging is an inevitable aspect of life, 5 amino 1MQ may be able to slow down its physiological and visual signs. It may help people to maintain a younger physiological state, prolong life and reduce the risk of age-related diseases by slowing down cell aging or cell aging.
Lose weight and fat.
5 Amino 1mq is outstanding in fighting obesity, because it may help to reduce fat. Inhibition of NNMT may reduce fat storage and enhance fat metabolism, thus helping to lose weight, and more importantly, it can achieve long-term fat reduction.
Muscle growth and repair
By ensuring that nutrients are more effectively used for muscle development and repair, improved metabolic efficiency can promote muscle growth and recovery. This may be especially useful in hard training, because muscle recovery is crucial at this time.
What role does 5 Amino 1mq play in the process of life?
1. Improve energy level and vitality:
5 Amino 1mq can significantly improve energy level by optimizing the body's metabolic activities. This energy boost helps to train harder, improve daily tasks, and enhance the sense of vitality.
2. Mental clarity and concentration:
Enhancing your energy with 5 Amino 1mq can not only improve your physical performance, but also significantly improve your psychological function. The increase of vitality can make you more focused, clearer and more focused, which is good for your daily cognitive tasks and exercise habits.
3. Inhibition of NNMT expression:
The main advantage of 5 Amino 1mq is that it can block NNMT, which is a key enzyme in our body. This effect has a profound impact on our metabolic health, helps to control weight, and even has potential anti-aging effect. By targeting NNMT, it can promote healthier metabolism, help to reduce unnecessary weight, and may play a role in prolonging youthful vitality, showing its overall impact on health and longevity.
4. Changes in metabolic health model:
amino molecules provide a revolutionary way to improve metabolic health by paying attention to NNMT, which may reset the natural process of the body and make the body healthier, leaner and more muscular.
How and where to buy 5 Amino 1mq wholesale?
You can trust our order, because we have a good record of selling legal educational drugs.
We conduct independent laboratory tests on all products and then sell them to our respected customers.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details,Click email ：allen@faithfulbio.com Or WhatsApp：+86 13137770562
FAQ：
Q1: What is the main target of action of 5 Amino 1mq?
A1: 5 Amino 1mq targets and inhibits NMNAT enzymes and adipose tissue-related metabolic pathways, regulating the energy metabolism process of adipocytes and reducing fat accumulation.
Q2: What regulatory effects does 5 Amino 1mq have on the body's metabolism?
A2: 5 Amino 1mq can accelerate the conversion of white adipose tissue to brown adipose tissue, improve the body's thermogenesis efficiency, and optimize the overall lipid metabolism level.
Q3: What is the core characteristic that distinguishes 5 Amino 1mq from ordinary fat-loss ingredients?
A3: 5 Amino 1mq focuses on regulating metabolism from within adipocytes, without affecting the central nervous system or heart rate, resulting in a gentler and more specific metabolic pathway.
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.
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