99% Tianeptine Sodium Salt CAS 30123-17-2

TIANEPTINE SODIUM is a tricyclic antidepressant drug, and its antidepressant mechanism is different from traditional tricyclic antidepressants. It can increase the reuptake of 5-HT in synaptic cleft and may have an effect on improving 5-HT neuronal conduction. Has no affinity for cholinergic or adrenergic receptors. The antidepressant efficacy is similar to tricyclic drugs, but the tolerability is better than tricyclic drugs. The 99% Tianeptine Sodium Salt provided by our company can increase the spontaneous activity of pyramidal cells in the hippocampus and accelerate their recovery after inhibition in animal experiments. At the same time, it can also increase the reabsorption of serotonin by neurons in the cerebral cortex and hippocampus.

How effective is the application of 99% Tianeptine Sodium Salt?

TIANEPTINE SODIUM can be used to treat mild, moderate, or severe depression, neurogenic and reactive depression, anxiety and depression related to physical discomfort, especially gastrointestinal discomfort, etc. It has an effect on anxiety disorders related to depression in the human body. It is a 5-HT reuptake agonist that can regulate the remodeling of hippocampus, amygdala, and dendritic cells, with a low incidence of side effects. It is a safe and effective antidepressant drug. In clinical applications, 99% Tianeptine Sodium Salt powder is rapidly and completely absorbed in the digestive tract, with a PPB of up to 94%. In the liver, complete metabolism is achieved through β - oxidation and N-demethylation, and the clearance of terminal T1/2 is short, taking 2.5 hours. A very small amount of the original drug (8%) is excreted from the kidneys, mainly its metabolites are excreted from the urine. The clearance of T1/2 in patients with renal insufficiency is prolonged by 1 hour.

What should be noted when using 99% Tianeptine Sodium Salt?

In animal experiments, it has been observed that Tianeptine Sodium can increase the spontaneous activity of pyramidal cells in the hippocampus, accelerate the recovery after functional inhibition, and accelerate the uptake of serotonin by neurons in the cerebral cortex and hippocampus. However, it should be noted that it also has significant side effects. For example: dry mouth, nausea, drowsiness, dizziness, headache, insomnia, nightmares, weight gain, constipation. In addition, there are also rare symptoms such as muscle pain, back pain, ventricular arrhythmia, orthostatic hypotension, palpitations, bradycardia, tremors, anxiety, irritability, hot flashes, facial flushing, bitter mouth, gastrointestinal bloating, abdominal pain, elevated serum alanine aminotransferase, rash, etc. In addition, as a unique mechanism antidepressant compound, its μ - opioid receptor agonistic activity also poses significant risks of abuse and safety. In most parts of the world, 99% of Tianeptine Sodium Salt api powder is strictly restricted or prohibited for non-medical use. Researchers should strictly abide by ethics and regulations, while the general public should fully understand its potential hazards and avoid improper use.

Why choose our 98% Tianeptine Sodium Salt ?

By choosing our Tianeptine Sodium Salt, you will gain a comprehensive advantage based on strict scientific compliance, excellent quality standards, and professional research and development support. We are well aware of the sensitivity and complexity of this compound in neuroscience research and specific medical applications, so we have established a full chain quality control system - from raw material screening to final product analysis, all following cGMP and ISO quality management standards, ensuring that the purity of each batch of products is stable above 99.5%, and equipped with complete third-party authoritative testing reports (including HPLC purity spectrum, mass spectrometry structure confirmation, residual solvent and heavy metal analysis), meeting the strict needs of global cutting-edge research institutions and compliant pharmaceutical companies. At the safety level, we control key impurities (such as byproduct isomers) below 0.1% by optimizing the synthesis pathway, and provide detailed safety data sheets (SDS) and stability study reports to help you accurately assess experimental risks. In response to the unique pharmacological duality of this compound (antidepressant potential and μ - opioid receptor activation risk), we further provide customized services to meet the needs of different dosage forms, specific concentration preparations, and compliance declaration support, helping researchers efficiently and compliantly promote topics such as neuroplasticity, stress response mechanisms, or exploration of new antidepressant targets. More importantly, we adhere to the premise of ethics and law, and all sales must pass scientific research qualification review to ensure that the products are only used in legal research scenarios. At the same time, we provide 24/7 technical consultation to assist customers in establishing compliant experimental plans and risk control processes. Choosing us is not only about choosing a high-purity chemical, but also about choosing a reliable partner who adheres to scientific ethics and specializes in the field of neuroscience.

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Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide 99% Tianeptine Sodium Salt powder etc. at a more favorable price. If you are interested, please leave a message.
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FAQ:

Q1: Do you offer free samples for testing?

Yes, we provide complimentary samples for most products. Customers only need to bear the shipping costs. This allows you to evaluate the quality firsthand. Additionally, for bulk orders, we offer competitive pricing and periodic promotions. Feel free to reach out to our sales team for more details.

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Payments are typically processed within one business day. Once your payment is received and verified, we will notify you immediately and proceed with order fulfillment. Shipment will be arranged promptly after payment confirmation.

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