What is the function of Zidovudine?And its dilemma.

Dec 09, 2021

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Zidovudine is designated as an antiviral drug, highly active in the virus, and approved by the US FDA for the treatment of AIDS (AIDS). Clinically used for AIDS or AIDS-related syndromes.


HIV and AIDS

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raw material Zidovudine has always been the first choice of anti-HIV drugs, but Americans reduced it to the second choice at the beginning of this year. Why? There are two reasons; 1. Zidovudine has the side effect of bone marrow suppression, and blood cells are produced by the bone marrow, so Zidovudine reduces leukocytes and affects the rise of CD4 cells (which is a kind of leukocytes). Some patients say: my virus can't be detected. Why don't CD4 cells grow well? There are many reasons, one of which is that you may use Zidovudine. 2. Zidovudine can also cause fat atrophy. Although it is lighter than Stavudine, it is much heavier than Tenofovir and Abakawe. Therefore, Americans regard Tenofovirand Abakawe as the preferred nucleoside drug.


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