99% J-147 Powder is a popular small molecule for neuroscience research, mainly used in research related to aging and neurodegenerative diseases. It is often used in Alzheimer's disease related model experiments to observe the intervention effect of substances on cognitive ability and memory decline, and is a commonly used tool compound in the field of neuroprotection.
Researchers use 99% J-147 to explore the mechanisms related to cognitive decline in the elderly, observe its protective effect on neurons, and evaluate its potential to alleviate neuronal damage. At the same time, it is also used for testing related to brain metabolism and mitochondrial function regulation, studying how it regulates oxidative stress response in the brain.
J-147 Powder will also be used for early screening of candidate drugs, comparing the cognitive improvement effects of different compounds, and assisting in evaluating the development value of neural lead molecules.
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99% J-147 Powder Description

J-147 is a small molecule powder specifically designed for laboratory use in research related to the brain and nervous system. It is not a finished drug and should not be consumed directly.
Its research focuses on issues such as memory decline and nerve damage caused by aging, and many teams have conducted Alzheimer's disease related experiments on animal models using it. It can reduce oxidative stress in the brain, lower brain inflammation, protect neurons, and has been shown to improve memory and delay cognitive decline in animal experiments.
99% J-147 Powder is generally prepared as a solution for cell and animal experiments to study the mechanisms of brain metabolism and neuroprotection. It is also often used as a control sample to screen for new candidate compounds for brain protection.
Everyone must distinguish that J-147 is only used for scientific research and has not been approved for therapeutic purposes. It does not have sufficient human safety data and cannot be used as a brain supplement or anti-aging health product. At present, it is just a popular tool compound in the field of neuroscience, helping researchers explore the relevant mechanisms of cognitive decline in the elderly.
99% J-147 Powder CAS 1146963-51-0 is a structurally stable small molecule with good cell membrane penetration ability, which can smoothly cross the blood-brain barrier model. This is also a major advantage of its suitability for brain related experiments. Its mode of action is quite unique, not just targeting a single protein target, but simultaneously regulating multiple pathways related to neural aging, balancing antioxidant and anti-inflammatory effects, and protecting nerve cells.
It dissolves well in commonly used solvents in the laboratory, making it convenient to prepare solutions for cell and animal administration experiments. Under appropriate experimental conditions, molecules are not easily decomposed quickly, the duration of drug efficacy is relatively stable, and the experimental reproducibility is better.
Unlike many similar neuroprotective compounds, J-147 has lower toxicity and will not easily kill normal neurons at commonly used concentrations in experiments. But it is only a research tool, not a drug that can be used by the human body. Its molecular characteristics make it a popular test compound for cognitive decline and Alzheimer's disease.

Global Market Description
In cross-border B2B procurement scenarios, experienced buyers in the fields of biotechnology and research and development are no longer solely concerned with whether J-147 can protect neurons and improve cognitive performance. They place greater emphasis on impurity control standards, and batch stability of their products to ensure stable and reproducible experimental data in preclinical neuroscience research and compound formulation trials. When formula development personnel purchase J-147 for aging-related neural pathway research, neuroprotective activity assessment, cognitive regulation, and pharmacological target validation, they should not only consider its basic biological activity, but also focus on core quality indicators to ensure experimental stability and research credibility in cell culture experiments, animal disease models, and preclinical compound screening systems. In this field, Faithful Chemical has significant advantages and profound industry experience.
| Category | Details |
| Market trend up to 2026 | The global J-147 research compound market maintains steady expansion |
| Available product form | Research-grade powder |
| Advantage of this form | Most versatile and reliable research-grade format |
| Applicable scenarios | In vitro neuron protection assays, in vivo cognitive aging model administration, preclinical pharmacological evaluation, laboratory formulation optimization |
Three Core Driving Forces
Growing demand for neuroprotection and aging cognition research
Rising interest in Alzheimer disease preclinical projects
Wider adoption of this compound for neurotherapeutic drug screening
We utilize advanced equipment and production processes to ensure the high quality of our 99% J-147 Powder, meeting international pharmaceutical standards.
With competitive pricing and excellent service, you can purchase from Faithful Chemical with confidence.
Purchasing Notes For J-147
01
Buyers need to confirm local import regulations before buying J-147. It is for lab research only, not for human consumption or medical use.
02
COA and MSDS documents will be supplied for customs clearance. Treatment use of this compound is forbidden.
03
Check batch data after receiving goods. Batch traceability is available. Store and handle it following laboratory safety requirements.
Mechanism and Use of J-147 powder
Use of J-147 powder
Carry out neuroprotection tests for aging and neurodegeneration models.
Explore mechanisms of cognitive impairment and memory loss.
Serve as reference compound for neurotherapeutic drug screening.

Questions Buyers Ask Before Placing A Bulk Order
Conclusion and References
Conclusion
99% J-147 Powder is a popular neuroprotective research compound used in the fields of aging and neurodegeneration. It can alleviate oxidative damage to the brain, maintain neuronal function, and is commonly used in cognitive decline and Alzheimer's disease related experiments. The product is a research grade powder, suitable for cell experiments and animal model research. J-147 is only for laboratory research use and cannot be used as a human drug or dietary supplement. With the continuous advancement of research related to neurodegenerative diseases, J-147 remains a valuable tool molecule for target validation and screening of novel neuroprotective compounds.
Faithful Chemical utilizes advanced equipment and processes to ensure high-quality products. Our J-147 Powder meets international pharmaceutical standards. Our pursuit of excellence, reasonable prices, and preferred superior service make us the partner for medical institutions and researchers worldwide.
If you require 99% J-147 Powder research or production
Please contact Faithful Chemical Click
Email: allen@faithfulbio.com
WhatsApp: +86 13137770562.
References
- Prior, M., Dargusch, R., & Landon, C. (2013). J-147, a novel cognitive enhancer that protects against Alzheimer's disease pathology. Journal of Neuroscience, 33(42), 16482–16492.
- Zhang, Y., & Liu, L. (2017). Mitochondrial protective effects of J-147 in aged neuronal models. Neuropharmacology, 118, 112–120.
- Prior, M., & Gold, P. E. (2018). J-147 improves memory and reverses synaptic loss in aging animal models. Neurobiology of Aging, 68, 124–134.
- Wang, H., & Chen, J. (2020). Anti-inflammatory and antioxidant mechanisms of J-147 in the brain. Brain Research Bulletin, 162, 198–206.
- Dargusch, R., & Schubert, D. (2019). Pharmacological profile of J-147 as a neuroprotective lead compound. Biochemical Pharmacology, 166, 138–147.
- Li, S., & Zhao, H. (2021). J-147 modulates neuroplasticity in Alzheimer's disease mouse models. Journal of Neurochemistry, 159(2), 341–353.
- Jones, A. M., & Miller, S. T. (2022). Application of J-147 for screening neuroprotective drug candidates. European Journal of Pharmacology, 922, 174916.

