Thioridazine Hydrochloride is a phenothiazine antipsychotic drug, which plays an antipsychotic role by blocking the postsynaptic dopamine D2 receptor in the brain. Similar to chlorpromazine, it has moderate or stronger antihypertensive effects, and moderate anticholinergic and sedative effects, but it has a light antiemetic effect and weak extrapyramidal effect.
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| interaction Proportion | Thioridazine Hydrochloride interaction |
Function and efficacy of Thioridazine Hydrochloride
1. It is mainly used to treat acute and chronic schizophrenia, especially schizophrenia with excitement, anxiety, and tension.
2. It can be used for mania and climacteric psychosis.
About the interaction of this product
When tricyclic antidepressants are used in combination with this product, the blood drug concentration is increased, the toxicity is enhanced and the anticholinergic effect is enhanced. Combined with belladonna, the anticholinergic effect is enhanced. Areca nut can increase the extrapyramidal reaction of this product. Combined with captopril and trazodone, it may lead to hypotension. The combination of atenolol and metoprolol with this product leads to hypotension and/or increased toxicity of this product. Sabril, Dofex Park Jung Su, Sotalol, Pimozide, Sparfloxacin, Gatifloxacin, Moxifloxacin, Gepafloxacin, levofloxacin, levomethadone, etc. will increase the toxicity to the heart when combined with this product. Combined with diazepam, this product may cause hyperglycemia. Combined with phenytoin, the blood concentration of phenytoin may increase or decrease, while the blood concentration of phenytoin decreases. When combined with epinephrine, it may lead to hypotension and tachycardia. When Ibrahimovic is used in combination with this product, the risk of arrhythmia increases. When Kagan is used in combination with this product, the therapeutic effect and/or adverse reactions of this product will increase. Combined with a lithium salt, this product may lead to dyskinesia, aggravation of extrapyramidal reaction, encephalopathy and brain injury, etc. When used in combination with pethidine, the inhibitory effect on the central nervous system and respiration is enhanced. Porphine sodium can aggravate the intracellular damage of light-sensitive tissues. Propranolol increases the toxicity of this product. When used in combination with amphetamines, the efficacy of both drugs decreases, and the risk of convulsion increases, while the antipsychotic effect of amphetamines decreases. Antacids reduce the curative effect of this product. Benzatropine, Ofunajun, procyclidine, and trihexyphenidyl hydrochloride led to a decrease in blood concentration and drug efficacy, while the anticholinergic effect was enhanced. Combined with cabergoline, the therapeutic effect is reduced. Cimetidine can reduce the curative effect of this product. Pratestosterone can reduce the efficacy of this product. This product can reduce the efficacy of guanethidine, norepinephrine, and fenmetreqin, and can also make levodopa ineffective. Phenobarbital can reduce the efficacy of this product. This product can reduce the efficacy of phenyl propyl coumarin and warfarin. Long-term use of this product may significantly reduce the response of thyrotropin to protein. This product may inhibit the antihypertensive effect of guannadir. When combined with evening primrose oil, meglumine, tramadol, and zotepine, the risk of convulsion increases. The company can provide related products. If you are interested, please contact us in time
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