Research continually demonstrates asiaticoside's soothing properties on skin, making it particularly suitable for sensitive skin types, as well as even being suitable for skin prone to eczema or rosacea.
Send your Inquiry for more details, Click email：sales4@faithfulbio.com
Product link
https://www.faithful-chemical.com/plant-extract/asiaticoside-skincare-cas-16830-15-2.html
What is asiaticoside?
Asiaticoside is a saponin compound found in Centella asiatica that has antioxidant activity and can protect against MPTP-induced neurotoxicity in rats by increasing the Bcl-2/Bax ratio.
Is Asiaticoside safe for skin?
ASIATICOSIDE USES FOR SKIN. To get most of the asiaticoside benefits for skin, you should use it in your daily skincare routine, AM and PM. As a gentle ingredient, it teams up incredibly well with all other skincare actives, even the less mild ones (think retinol, vitamin C, AHAs, and salicylic acid).
What is the use of Asiaticoside?
Asiaticoside and madecassoside are also used extensively in treating skin abnormalities, burn injuries, ischaemia, ulcers, asthma, lupus, psoriasis and scleroderma.
What is the formula for Asiaticoside?
Asiaticoside (chemical formula: C48H78O19, molecular weight: 959.12)is mainly extracted from the dried whole grass of Centella asiatica, which can promote wound healing and is often used in the treatment of trauma, keloid and scleroderma.
What is the mechanism of action of Asiaticoside?
Asiaticoside (AC) is a naturally occurring phytoconstituent that aids in wound healing by stimulating collagen biosynthesis. However, the physical properties of AC, such as its high molecular weight (959.12 g mol⁻¹), poor water solubility, and low permeability, restrict its therapeutic benefits.
Send your Inquiry for more details, Click email：sales4@faithfulbio.com
Studies have confirmed that Asiaticoside can promote fibroblast proliferation and extracellular matrix synthesis during the process of wound healing: When human fibroblasts were intervened with Asiaticoside, the gene expression profile showed that the genes responsible for cell proliferation and extracellular matrix synthesis were upregulated, and the mRNA and protein levels encoding type I and type III collagen significantly increased. At the same time, it could increase cell adhesion and migration and promote cell proliferation. The results of the in vivo trauma experiment revealed that Asiaticoside had a significant effect in promoting wound healing. On the 7th and 12th days after trauma, the healing rate was significantly higher than that of the blank control group. The research results of rat skin histopathology show that Asiaticoside can promote the regeneration of collagen and skin accessory organs.
Some studies also suggest that Asiaticoside has a dual effect of promoting wound healing and inhibiting scar formation. Asiaticoside is mainly used for the prevention and treatment of scars after wound healing. Recent clinical findings have shown that it also has a good therapeutic effect on unhealed burn wounds, can shorten the wound healing time, and inhibit excessive scar hyperplasia. Asiaticoside may promote collagen maturation and wound healing by influencing the expression of heat shock protein 47, thereby reducing scar formation.
Studies have shown that Asiaticoside can inhibit the proliferation of fibroblasts in scar tissue and simultaneously suppress the expression of type I and type III collagen mRNA in scar fibroblasts. This confirmed that Asiaticoside inhibits the collagen secretion function of overly active fibroblasts by suppressing them, thereby playing a role in inhibiting collagen hyperplasia and intervening in scar formation.
Other studies have found that Asiaticoside mainly exerts its effect by inhibiting scar hyperplasia and blocking fibroblast proliferation through the Smad pathway.
Application
Asiaticoside is the main component in the medicinal herb Centella asiatica. The mixture of Asiaticoside A and Asiaticoside B has pharmacological effects such as promoting wound healing, anti-wrinkle, anti-inflammation, anti-depression, and enhancing intelligence. By comparing the pharmacological effects of Asiaticoside in promoting wound healing and treating scars, it can be found that the anti-inflammatory, antidepressant and intelligence-promoting pharmacological effects of total saponins from Centella asiatica may be mainly played by Asiaticoside A and Asiaticoside B.
Send your Inquiry for more details, Click email：sales4@faithfulbio.com
1. Do you have a problem whit delivery to my country?
A:We have warehouses in Europe, America and Australia. At the same time, if you are from Europe, the goods can be sent from Germany, and if you are from America or Canada, the goods can be sent from California.
2. How is the goods packed?
A:We usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.
3. When will you sent out the goods after successful payment?
A:Normally the order will be delivery within 3-7 days after the order confirmed, except the customized products.
4. How to proceed order?
A:Please Let me konw the product you are looking for,quantity and the destination country wihch help me to give you a right price;After you confirm all details of order, pay money in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.
Send your Inquiry for more details, Click email：sales4@faithfulbio.com