Mepivacaine is a local anesthetic of the amide-type. Mepivacaine is used in any infiltration and local anesthesia. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine)
Mepivacaine was originally synthesized in Sweden at the laboratory in 1956. It is supplied as the hydrochloride salt of the racemate, which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties.
Warnings: Spinal numbing medications can have long-lasting or permanent effects on certain body processes.
What are the uses of this product?
Mepivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain. Mepivacaine is used as a local (in only one area) anesthetic for an epidural or spinal block. It is used for local infiltration anesthesia (nerve conduction block type) in oral and dental treatment.Mepivacaine may also be used for other purposes not listed in this medication guide.
What should we pay attention to when using this product?
It may be inhibited or excited by mepivacaine hydrochloride, resulting in involuntary eye movement, nonsense, headache, nausea, and other symptoms. Clinically, there have been dyspnea, bradycardia, hypotension, etc. Patients with sulfite bronchial asthma have drug allergic reactions due to their allergy to sulfite. For example urticaria, edema, etc. The following cases are rare, but we must consider them clearly before using them. Patients with adrenaline cardiovascular disease and hypertension are sensitive to adrenaline, and local ischemia or tissue necrosis may occur. Do not use this product if you are allergic to amino anesthetics or similar drugs. Patients with serious cardiovascular disease, taking compound tricyclic antidepressants and monoamine oxidase treatment.
[precautions] for the same patient, one course of treatment can only be used once, and it must be used immediately once it is opened. People with liver and kidney dysfunction should avoid using this anesthetic as far as possible. Avoid anesthesia for infected or inflamed parts. The use should be carried out slowly and must be withdrawn. This medicine contains vasoconstrictor, so it cannot be reused in the same area to avoid tissue necrosis in this area
What anesthetics are commonly used in dental implant surgery?
Patients without hypertension generally choose articaine adrenaline.
However, there are many problems with articaine. In recent years, the production and supply of articaine have not kept up, and the price has risen rapidly in a few years
Lidocaine, Mepivacaine, etc, and so on are often chosen now.
The toxicity and duration of different anesthetics are different, and doctors will choose according to the actual situation.
In case of serious hemostatic problems, it needs to be used with 1% diluted adrenaline (adrenaline has the effect of raising blood pressure, which cannot be used by patients with hypertension. Patients with hypertension can use anesthetics alone, but can't use articaine); Patients with partial anesthetic tolerance or other reasons should be given nerve block.
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