How long does dapoxetine make you last in bed?

Dapoxetine hydrochloride is a new serotonin reuptake inhibitor with recognized efficacy in the treatment of premature ejaculation,

Premature ejaculation is one of the most common male sexual dysfunction, which will have a great impact on a patient's self-esteem and husband-wife relationship. Tricyclic antidepressants and clomipramine are the most widely used drugs for the treatment of premature ejaculation. In addition, there are adrenergic receptor antagonists, benzodiazepines, gabapentin and so on. Serotonin reuptake inhibitor is the most widely used, effective, and rapid research drug for the treatment of premature ejaculation.

How long can dapoxetine hydrochloride last?

A randomized, double-blind, placebo-controlled trial confirmed the efficacy of dapoxetine in the treatment of PE.

Effect of dosage on PE effect?

Different doses have different effects on different types of PE. Compared with dapoxetine 30 mg, dapoxetine 60 mg significantly improved the mean vaginal ejaculation latency (IELT) in lifelong PE men, but no difference was observed in acquired PE men.

Effect of taking time on PE effect?

Taking it 1-3 hours before sexual behavior can prolong the IELT of men aged 18 to 64 with PE and increase the sense of control and sexual satisfaction.

Taking this product can effectively overcome PE psychological barriers

Because PE has a great relationship with personal pain and interpersonal difficulties, especially the serious symptoms of PE caused by psychological obstacles are a common problem. In clinical treatment, dapoxetine can help PE men overcome this emotion and greatly alleviate the psychological pressure caused by psychological obstacles.

What is the difference between other similar products and this product?

In the early stage, because there was no drug specifically approved for the treatment of PE in the United States and some other countries, other SSRIs, such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram, have been used for the treatment of PE.

The analysis showed that compared with dapoxetine, the use of these conventional antidepressants increased IELT by 2 to 9 times, higher than baseline. However, these SSRIs need to be taken on time every day to achieve real efficacy, and they all have a long half-life, which will increase the risk of drug accumulation, produce drug resistance, and induce permanent PE or other serious problems.

What is the pharmacokinetics of dapoxetine hydrochloride?

Dapoxetine is insoluble in water but can be quickly absorbed by the human body. The maximum plasma concentration (Cmax) was reached 1-2 hours after oral administration. Details can be seen in the table above (C max and AUC (area under plasma versus time curve) are dose-dependent. The Cmax and TM (time required to obtain the maximum plasma concentration) after a single dose of dapoxetine 30 mg and 60 mg were 297 and 498 ng / ml at 1.01 and 1.27 hours, respectively.) Whether you eat before and after taking and what kind of product you eat have little impact on this product.

The metabolites of dapoxetine are excreted in urine through the kidney. The final half-lives of single doses of 30 mg and 60 mg are 18.7 and 21.9 hours, respectively.

Why should we choose dapoxetine hydrochloride?

Dapoxetine is a quick-acting SSRI. According to the relevant pharmacokinetic knowledge of this product, we can understand that this product can be absorbed faster and discharged from the body within a few hours after taking it. At the same time, this product is less disturbed by other factors. This makes its advantages more reassuring when we use it.

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