Tripelennamine Hydrochloride CAS 154-69-8
Product Name:TRIPELENNAMINE HYDROCHLORIDE
Synonym:Ahistamin;Antiallergicum medivet;TRIPELENNAMINEHYDROCHLORIDE
CAS NO.:154-69-8
EINECS NO.:205-833-5
Molecular Formula:C16H22ClN3
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 5-10 days
Store & Shelf life: Cool & dry place; 24 months
Description
Product description

Tripelennamine hydrochloride is a classic first-generation antihistamine compound. Due to its stable physicochemical properties and well-defined biological activity, it has long been used to improve and alleviate allergy-related symptoms. Its core mechanism of action is the specific blocking of histamine H1 receptors in the human body. This effectively antagonizes the series of stress responses triggered by the release of histamine after exposure to allergens, inhibiting the spread of the allergic chain reaction at its source and reducing abnormal stress in the body. Compared to ordinary soothing ingredients, its anti-allergic activity is more potent and its coverage is broader. It can specifically improve various discomforts caused by skin and mucous membrane allergies, including sudden itching, redness, hives, eczema-like discomfort, and common allergy symptoms such as nasal discomfort, frequent sneezing, and abnormal runny nose caused by mucous membrane sensitivity.
Aside from powerful anti-allergic performance, Tripelennamine hydrochloride has mild sedative and anticholinergic properties. It eases allergic discomfort and relieves associated restlessness, suitable for daily relief of mild and moderate allergic symptoms. Its effect on the central nervous system may lead to drowsiness, dizziness, dry mouth and a relaxed mental state. Users are therefore recommended to avoid concentration-intensive tasks, precision machinery operation and high-speed activities.

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COA
| Test Item | Specification | Result |
| Appearance | White or off-white crystalline powder | White crystalline powder |
| dentification | Complies with IR spectrum | Complies |
| Melting Point | 192-193℃ | 192.5-193.0℃ |
| Purity(HPLC) | ≥98.0% | 99.2% |
| Water Content | ≤0.5% | 0.28% |
| Residue on Ignition | ≤0.1% | 0.05% |
| Heavy Metals(Pb) | ≤10 ppm | <5 ppm |
| Individual Impurity | ≤0.5% | 0.18% |
| Total Impurities | ≤2.0% | 0.55% |
| Solubility | Soluble in methanol,slightly soluble in water |
Complies |
| Conclusion | Conform with enterprise specification | |
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Density 1.20
Boiling point 387.8ºC at 760 mmHg
Melting point 192-193ºC
Molecular formula C16H22ClN3
Molecular weight 291.81900
Flash point 188.3ºC
Exact mass 291.15000
PSA 19.37000
LogP 3.45180
Tripelennamine Hydrochloride Mechanism of Action
Competitive Blocking of H1 Histamine Receptors: It preferentially binds to histamine H1 receptors in target tissues, preventing histamine from binding to these receptors and blocking various histamine-induced allergic reactions, thus alleviating allergy-related discomfort at its source.
Central Sedative Effect: It crosses the blood-brain barrier and acts on the central nervous system, producing a mild sedative effect, calming irritability and anxiety caused by allergies.
Anticholinergic Effect: It antagonizes intracellular cholinergic receptors, inhibiting abnormal glandular secretion and smooth muscle reactions, which are also major causes of somatic symptoms such as dry mouth.
Inhibition of Allergic Cascade Reactions: It reduces the transmission of sensitizing signals, weakens a series of secondary reactions such as vasodilation and increased permeability, and alleviates external manifestations such as redness and itching.
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Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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FAQ
01. What are the effects of anticholinergic properties?
It can regulate glandular secretion and smooth muscle function, and is a major cause of symptoms like dry mouth.
02. What typical allergy-related symptoms can it relieve?
Tripelennamine hydrochloride can improve various symptoms such as itchy skin, redness, nasal discomfort, and frequent sneezing.
03. Where can I buy Tripelennamine hydrochloride?
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