Product Introduction
Sitagliptin phosphate monohydrate is a dipeptidyl peptidase IV (DDP-4) inhibitor used to treat type 2 diabetes. It is a new type of hypoglycemic drug that can improve the body's ability to reduce excessive blood sugar levels. By inhibiting the activity of the enzyme, it relatively increases the levels of naturally occurring incretins, including glucagon-like peptide-1 and glucose-dependent insulinotropic peptide, thereby triggering the pancreas to increase insulin production and stop the liver from producing glucose, ultimately reducing blood sugar concentrations. The characteristics of this product are that it can reduce hunger while stimulating insulin secretion, and it will not cause weight gain, hypoglycemia, or edema. It is suitable for diabetic patients with poor blood sugar control and frequent hypoglycemia.
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| Sitagliptin phosphate monohydrate Picture | Sitagliptin phosphate monohydrate MF |
Product Application
Sitagliptin phosphate monohydrate can significantly reduce the level of glycated hemoglobin (HbA1c) in patients with type 2 diabetes as a monotherapy. When used in combination with metformin or TZDs, it has a significant adjuvant therapeutic effect and can play a role in the three main defects of type 2 diabetes: insulin resistance, β-cell dysfunction (reduced insulin release), and α-cell dysfunction (failure to inhibit liver glucose production).
Specificity studies were carried out by stress degradation study, the parameter was evaluated based on the adequate resolution between analyte and degradation products as well as the ability of the method to detect analyte in presence of other products.The data was shown in figs.
The linearity of calibration curves (peak area vs concentration) in pure solution was checked over the concentration range of 20-150 μg/ml of SIT and 8-60 μg/ml of SIM. The regression line relating standard concentrations of drug using regression analysis, the calibration curves were linear in the studied range and equations of the regression analysis were obtained, r2=0.9998 for SIT and r2= 0.9993 for SIM.
Product Specification
| Item | Specification | Result |
| Assay | 98% | 99.35% |
| Flavor & Odor | Characteristic | Complies |
| Appearance | White to off-white powder | Complies |
| Particle size | 100% pass 80 mesh | Complies |
| Loss on Drying | ≤5.0% | 1.05% |
| Bulk density | 40-60g/100ml | Complies |
| Sulphated Ash | ≤3.0% | 2.05% |
| Heavy Metal | ≤20mg/kg | Complies |
| Pb | ≤3mg/kg | Complies |
| As | ≤1mg/kg | Complies |
| Hg | ≤0.1mg/kg | Complies |
| Cd | ≤1mg/kg | Complies |
| Total of bacteria | ≤1000cfu/g | Complies |
| Fungi | ≤100cfu/g | Complies |
| Salmgosella | Negative | Complies |
| E.Coli | Negative | Complies |
| Conclusion | Conform with the enterprise standard | |
How To Obtain Samples Sitagliptin phosphate monohydrate?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Sitagliptin phosphate monohydrate.
The Best Sitagliptin phosphate monohydrate Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Sitagliptin phosphate monohydrate?
Faithfulbio specialize in Sitagliptin phosphate monohydrate for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use Sitagliptin phosphate monohydrate for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Sitagliptin phosphate monohydrate?
Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!
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