Products Description

Gemfibrozil Powder is a useful medication for the reduction of triglycerides in patients with very high triglycerides serum levels. It is also approved for decreasing the risk of developing coronary heart disease (Type IIb), particularly in patients without a history of subsisting coronary heart disease symptoms.
Gemfibrozil is used for hyperlipidemia. It is suitable for patients with severe type Ⅳ or type Ⅴ hyperlipoproteinemia, high risk of coronary heart disease and ineffective treatment such as diet control and weight reduction. It is also suitable for patients with Ⅱb type hyperlipoproteinemia, high risk of coronary heart disease and ineffective treatment with diet control, weight reduction and other lipid-regulating drugs.
Gemfibrozil Powder can promote the decomposition of peripheral fat, reduce the intake of free fatty acids in the liver and reduce the formation of triglycerides in the liver, and inhibit the synthesis of very low density lipoprotein apolipoprotein and reduce the production of very low density lipoprotein. It can reduce blood triglyceride and increase blood high density lipoprotein level, and slightly reduce blood concentration of low density lipoprotein cholesterol, but in type ⅳ hyperlipoproteinemia, it may increase low density lipoprotein. Comparative studies have shown that it can reduce the occurrence of sudden death of severe coronary heart disease and myocardial infarction.

Send your Inquiry for more details, Click email:sales4@faithfulbio.com
COA
| ltems | Standard | Results |
| Appearance | White or off-white solid powder | Complies |
| Identification | By IR By HPLC |
Complies Complies |
| Solubility | Soluble in DMF, sparingly soluble in THF. slightly soluble in methanol and acetonitrile. very sightly soluble in ethanol and dichloromethane, insoluble in water. |
Complies |
| Polymorphic Form | Polymorphic form 1 | Complies |
| Melting Point | 211°C~216°C | 212.8℃~214.9℃ |
| Water Content | ≤0.50% | 0.10% |
| Heavy Metals | ≤ 20ppm | Complies |
| Residue on lgnition | ≤0.20% | 0.09% |
| Related Substance | Any single impurity: ≤0.10% Total lmpurities: ≤1.00% |
0.06% 0.16% |
| Assay(on the anhydrous basis) | 98.0%-102.0% | 99.94% |
| Particle Size | D90: ≤100μm | Complies |
| Conclusion | Conform with enterprise specification | |
Send your Inquiry for more details, Click email:sales4@faithfulbio.com
Product nature
-
Density 1.1109 (rough estimate)
-
Flash point 141.6 °C
-
Melting point 59.0 to 63.0 deg-C
-
Boiling point 159°C/0.02mmHg(lit.)
-
Refractive index 1.5020 (estimate)
-
Merck 4388
What is the mechanism of action of gemfibrozil?
These data suggest that gemfibrozil increases plasma HDL levels by stimulating their synthesis. Increased transport (turnover) of HDL induced by gemfibrozil may be significant in increasing tissue cholesterol removal in these patients.
Is gemfibrozil and atorvastatin?
Using gemfibrozil together with atorvastatin can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death.
Does gemfibrozil lower triglycerides?
Gemfibrozil Powder is a useful medication for the reduction of triglycerides in patients with very high triglycerides serum levels. It is also approved for decreasing the risk of developing coronary heart disease (Type IIb), particularly in patients without a history of subsisting coronary heart disease symptoms.
Send your Inquiry for more details, Click email:sales4@faithfulbio.com

why choose us
Our Factory


Package

Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email:sales4@faithfulbio.com
Hot Tags: gemfibrozil powder cas 25812-30-0, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China






