Erythromycin Thiocyanate CAS 7704-67-8
Product Name:Erythromycin thiocyanate;ERYTHROMYCIN THIOCYNATE;ErythroMicyn thiocyanate;ERTHROMYCIN THIOCYANATE
CAS NO.:7704-67-8
Molecular formula：C38H68N2O13S
Purity & Grade: 99% HPLC; Medicine grade
MOQ & Package: 100g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 24 months
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
Certificate:COA; HPLC; MSDS; TDS,etc.
Description
What is erythromycin thiocyanate?
Erythromycin thiocyanate is a commonly used macrolide antibiotic erythromycin thiocyanate. Erythromycin thiocyanate is a veterinary drug, which is used to treat infections of Gram-positive bacteria and pathogens. It has been widely used as an "animal growth promoter" abroad, and it ranks as one of the four major export veterinary antibiotic products in China along with tylosin, tetracycline hydrochloride and oxytetracycline. In addition, erythromycin thiocyanate is also an important intermediate for the synthesis of mainstream macrolide antibiotics, such as erythromycin, roxithromycin, azithromycin and clarithromycin.
Erythromycin thiocyanate powder is white or white-like crystal or crystalline powder; Odorless; Slightly hygroscopic. Soluble in methanol or ethanol, slightly soluble in water or chloroform.
Erythromycin thiocyanate acts by binding to the 50S ribosomal subunit of bacteria, and inhibits the synthesis of RNA-dependent protein by blocking the trans-peptide and/or translocation reaction, without affecting the synthesis of nucleic acid. Erythromycin thiocyanate has shown anti-tumor properties and neuroprotective effects in different fields.
| Product name | erythromycin thiocyanate |
| CAS | 7704-67-8 |
| Molecular formula | C38H68N2O13S |
| Molecular weight | 793.02 |
| EINECS Number | 231-723-1 |
| Storage condition | Store at -20°C, away from moisture |
| Melting point | 166-167 °C |
| Solubility | DMSO：100 mg/mL(126.10 mM; Need ultrasound) |
| Appearance | White to off-white powder |
| Stability | hygroscopicity |
| LogP | 2.18288 |
What is the pharmacological action of erythromycin thiocyanate?
Erythromycin thiocyanate is a semi-synthetic macrolide antibiotic with a wide range of anti-pathogens, which has a strong inhibitory effect on many mycoplasma and most gram-negative bacteria. By binding to bacterial ribosome 50S subunit, it inhibits ribosome movement and affects protein synthesis in bacterial cells. There are high concentrations in polymorphonuclear leukocytes and macrophages. Therefore, the adhesion and chemotaxis functions of these cells are enhanced. When infected, these cells can phagocytize and dissolve bacteria, have stable gastric acid, good absorption, wide distribution, high blood concentration, strong tissue permeability, high concentration in tissues such as lungs and tonsils, and 1-2 times higher antibacterial activity than red toxin. It is resistant to penicillin-resistant Staphylococcus aureus and has low toxicity.
Product Specification
| Item | Specification | Results |
| Appearance | White or almost white crystalline powder | Almost white crystalline powder |
| Melting point | 165-168°C | 166-167°C |
| Identification | (1)The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the assay. | Complies |
| (2)UV absorption Max. at 266nm. | Complies | |
| (3)IR spectra is consistent with CRS. | Complies | |
| PH | 6.0-8.0 | 7.6 |
| Endotoxin | 0.33EU/mg max | Confirm |
| Related substances | Individual impurity not more than 0.5% | 0.35% |
| Total impurities not more than 2.0% | 0.76% | |
| Loss on drying | ≤6.0% | 3.25% |
| Residue on ignition | ≤0.1% | 0.02% |
| Heavy metals | ≤20ppm | Confirms |
| Assay | 98.5%min | 99.30% |
| Conclusion | Conform USP Standard. | |
What is the use of erythromycin thiocyanate?
1. Erythromycin thiocyanate is mainly used to treat infections caused by penicillin-resistant staphylococci and streptococci.
2. Erythromycin thiocyanate is an antibiotic.
3. It can be used as an alternative medicine for animals allergic to penicillin.
4. It is a broad-spectrum antibiotic, which can be used to treat various bacterial infections, such as skin and soft tissue infections, respiratory tract infections, urinary tract infections, etc. It can inhibit the protein synthesis of bacteria, thus resisting the growth and reproduction of bacteria.
HTML5 atlas of erythromycin thiocyanate
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What is the difference between erythromycin thiocyanate and erythromycin?
1. Erythromycin Thiocyanate is a sulfonamide antibiotic, and its main component is erythromycin. Erythromycin has broad-spectrum antibacterial effect, especially on gram-positive bacteria and some protozoa. Erythromycin thiocyanate is often used to treat and prevent infectious diseases in livestock and poultry veterinary drugs.
2. Erythromycin is a broad-spectrum antibiotic, belonging to macrolide antibiotics. It can inhibit the growth and reproduction of bacteria, so it is widely used in the veterinary field to treat infectious diseases such as respiratory tract, urinary tract and skin. Erythromycin has a wide range of applications and is one of the important components in veterinary drugs for livestock and poultry.
3. Erythromycin thiocyanate is mainly used to treat infectious diseases of livestock and poultry, such as respiratory tract infection and urinary system infection. Its mechanism of action is to achieve antibacterial effect by inhibiting the synthesis of bacterial proteins. In the daily management of farms, erythromycin thiocyanate is also often used to treat diseased animals in groups to prevent the spread of diseases.
Erythromycin is more widely used in livestock and poultry veterinary drugs. It is highly sensitive to a variety of bacteria, so it can be used to treat a variety of infectious diseases. Respiratory tract infection and digestive system infection are common problems in animal husbandry, and erythromycin can effectively deal with these problems and improve the production performance of livestock and poultry.
4. The application of erythromycin thiocyanate and erythromycin is an important veterinary medicine measure in livestock and poultry breeding. Through scientific and rational use, the health of livestock and poultry can be maintained, the breeding efficiency can be improved, and the quality and safety of livestock products can be strongly supported.
Is Erythromycin Thiocyanate stronger than amoxicillin?
1. Erythromycin thiocyanate belongs to macrolide antibiotics, while amoxicillin belongs to penicillin antibiotics.
2. Erythromycin thiocyanate is mainly used to treat discomfort caused by bacterial infection, such as respiratory tract infection and skin infection. Amoxicillin is mainly used to treat discomfort caused by sensitive bacteria, such as respiratory tract infection, urinary system infection and digestive tract infection.
3. Erythromycin thiocyanate is not suitable for patients allergic to this drug, but amoxicillin is not suitable for patients allergic to penicillin and patients allergic to cephalosporins.
This shows that when used properly, amoxicillin and erythromycin thiocyanate are equally effective, but amoxicillin is more effective than erythromycin thiocyanate in leading to the completion of treatment and subsequent negative test of cure.
What are the precautions of Erythromycin Thiocyanate powder?
1. Cross-allergy: When a patient is allergic to one macrolide, he can also be allergic to other macrolides.
2. The influence of drugs on the test value or diagnosis: Rhodotorula can interfere with the fluorescence determination of Higerty method, and make the determination value of urinary catecholamine appear false increase.
3. It shall be inspected or monitored before and after use.
How and where to buy Erythromycin Thiocyanate Powder wholesale?
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We conduct independent laboratory tests on all products and then sell them to our respected customers.
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure, or prevent any disease.
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