Febuxostat Powder CAS 144060-53-7

Febuxostat Powder CAS 144060-53-7

Product Name:Febuxostat powder;Febuxostat
CAS NO.:144060-53-7
Molecular Formula:C16H16N2O3S
Purity & Grade: 99% HPLC; Medicine grade
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 24 months
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
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Description

Product Introduction

Febuxostat powder is a new generation of xanthine oxidase inhibitors, clinically used to treat hyperuricemia (gout). Its structure is completely different from the xanthine oxidase inhibitor drugs developed 40 years ago. It is a new and highly effective non-purine xanthine oxidase selective inhibitor. Xanthine oxidase is a key enzyme that promotes uric acid production. Febuxostat can reduce the level of uric acid in the blood of patients with hyperuricemia and gout, and it is metabolized by the liver and does not rely on kidney excretion.

Febuxostat powder Picture

Febuxostat powder MF

Febuxostat powder Picture Febuxostat powder MF

 

Product Application

Febuxostat powder is the world's latest new generation non-purine selective xanthine oxidase inhibitor, which acts on the oxidase with high selectivity, reduces uric acid synthesis in the body, and reduces uric acid concentration, thereby effectively treating uric acid diseases. It has a significant inhibitory effect on both oxidized and reduced XOR, so its effect of reducing uric acid is more powerful and lasting; Febuxostat is a non-purine XOR inhibitor, so it has better safety.

 

 

Febuxostat effect diagram1

Febuxostat powder is a non-purine selective xanthine oxidase inhibitor. It works by non-competitively blocking the molybdenum pterin center, the active site of xanthine oxidase. Xanthine oxidase is required to oxidize hypoxanthine and then xanthine to uric acid. Therefore, febuxostat inhibits xanthine oxidase, thereby reducing uric acid production. Febuxostat inhibits both oxidized and reduced xanthine oxidase by binding tightly to the molybdenum pterin site.

Results: Febuxostat has three active metabolites in humans, which are formed mainly by a number of cytochrome P450 liver enzymes (CYP1A1, 1A2, 2C8, 2C9). One of them is a dicarboxylic acid, the other two are hydroxylated derivatives. These, as well as the original drug, are further glucuronidated, mainly by the enzymes UGT1A1, 1A8, and 1A9.

Febuxostat structure diagram1

 

Product Specification

Item Specification Result
Appearance White to off-white Powder Conforms
Specific Rotation[α]D20 -84.5°~ -86.0° -84.7°
State of Solution NLT98.0% 98.46%
Chloride NMT 0.020% NMT0.020%
Ammonium NMT0.02% NMT 0.02%
Sulphate NMT0.020% NMT 0.020%
Iron NMT10ppm NMT10ppm
Heavy Metals (Pb) NMT10ppm NMT10ppm
Arsenic NMT1ppm NMT1ppm
Other Amino Acids Chromatographically not detectable Conforms
Loss on Drying NMT0.30% 0.20%
Residue on Ignition NMT0.10% 0.06%
Assay 99.0% ~101.0% 99.65%
PH 5.9~6.9 6.1
Conclusion Conform with the enterprise standard

 

How To Obtain Samples Febuxostat powder?

Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Febuxostat powder.

 

The Best Febuxostat powder Manufacturer And Supplier

Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.

We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.

 

Why Choose Faithfulbio Febuxostat powder?

Faithfulbio specialize in Febuxostat powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.

 

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A variety of shipping methods for you to choose

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL,Germany DHL,Germany DPD,
UPS,USPS,FedEx,TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA,
and customers in Europe and America can
enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

kindly note: Use Febuxostat powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.

 

Where To Buy Febuxostat powder?

Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!

 

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