Forskolin Powder CAS 66575-29-9

How to extract Forskolin powder?

Product Specification

Conclusion：Conform with enterprise specification .

Where is Forskolin powder usually used?

Forskolin powder is a compound commonly used in scientific research, mainly derived from the Indian flowering plant Coleus Forskolin. Here are some common uses of Forskolin powder:
1. Increase intracellular cAMP levels: Forskolin powder directly activates adenylate cyclase (AC) by acting on catalytic subunits, thereby causing an increase in intracellular cyclic adenosine monophosphate (cAMP) levels.
2. Smooth muscle relaxants and vasodilators: Forskolin can exert the functions of smooth muscle relaxants and vasodilators in a concentration dependent manner, while affecting cytoplasmic calcium ion levels and calcium ion sensitivity of contractile components.
3. Detection of adenylate cyclase expression, regulation, and G protein signaling pathway: Forskolin can interact with glucose transporters and certain ion channels, making it suitable for detecting adenylate cyclase expression, regulation, and G protein signaling pathway.
4. Enhance neuronal differentiation ability: Forskolin is used in several differentiation schemes to enhance neuronal differentiation ability.
It should be noted that Forskolin powder is not a clinical drug and can only be used for scientific research purposes. It cannot be used for diagnosis or clinical purposes. For safety and health reasons, it is recommended to wear lab coats and disposable gloves during operation

What are the effects of Forskolin ?

Forskolin powder, as a natural compound, has multiple biological activities and potential health benefits. Here are some of the main effects of Forskolin powder:
1. Increase cAMP levels: Forskolin can directly activate adenylate cyclase (AC), causing an increase in intracellular cyclic adenosine monophosphate (cAMP) levels.
2. Smooth muscle relaxation and vasodilation: Forskolin exerts its functions as a smooth muscle relaxant and vasodilator in a concentration dependent manner, while affecting cytoplasmic calcium ion levels and calcium ion sensitivity of contractile components.
3. Promote neuronal differentiation: Forskolin is used in several differentiation schemes to enhance neuronal differentiation ability.
4. Inhibit platelet aggregation: Forskolin can inhibit platelet aggregation, promote vasodilation, bronchiectasis, and thyroid hormone secretion, and stimulate fat breakdown.
5. Reduce blood pressure and intraocular pressure: Forskolin promotes cAMP production, which can inhibit degranulation of eosinophils and mast cells and histamine release, thereby reducing blood pressure and intraocular pressure.
6. Anti inflammatory effect: Forskolin inhibits the binding of platelet activating factor (PAF), which is independent of cAMP formation and may be achieved by Forskolin's direct action on PAF or by interfering with the binding of PAF to its receptors.
7. Stimulate fat breakdown: Forskolin promotes fat breakdown.
8. Promoting angiogenesis: Forskolin stimulates angiogenesis to function by regulating two different signaling pathways: PKA dependent VEGF expression and Epac mediated PI3K/Akt/eNOS/NO signaling pathway cross-talk.
It should be noted that although Forskolin exhibits the potential effects mentioned above, its specific application and safety still need more scientific research and clinical trials to verify. Before using Foscolin powder, it is recommended to consult with professional medical personnel and follow their guidance.