Ibrutinib Powder CAS 936563-96-1

Name: China Ibrutinib Powder CAS 936563-96-1 Suppliers, Manufacturers, Factory - Wholesale Price - Faithful Biotech
Brand: Faithful
SKU: 257011733

Product Name:Ibrutinib
Synonym:Imbruvica;PCI 32765;CRA-032765;Ibrutinib
CAS NO.:936563-96-1
EINECS NO.:805-642-2
Molecular Formula:C25H24N6O2
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months

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Description

Product description

Ibrutinib Powder is a Bruton tyrosine kinase (BTK) inhibitor for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL). Ibrutinib Powder can bind to BTK targeting, which is necessary for the formation, differentiation, information transmission and survival of B lymphocytes, irreversibly inhibit the activity of BTK, and effectively inhibit the proliferation and survival of tumor cells.

Ibrutinib Powder is a small molecule BTK inhibitor, which can selectively covalently bind to cysteine residue (Cys-481) at the active site of BTK, irreversibly inhibit the activity of BTK, and then inhibit the activation of BCR signaling pathway, effectively preventing tumor migration from B cells to lymphoid tissue suitable for tumor growth. Reduce the malignant proliferation of B cells and induce cell apoptosis, thus play a role in the treatment of CLL and MCL.

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Items	Specifications	Results
Appearance	White to off-whitecrystalline powder	White crystalline powder
Identification	H-NMR,MS	Complies
Solubility	Soluble in DMSOandTHF slightlysoluble in MeOH, insoluble in H₂O	Soluble in DMSO and THF slightly solublein MeOH, insoluble in H₂O
Melting point	154~159℃	155.9℃
Specific rotation	-122~-132°	-128.6°
Residual Solvents	MeOH≤0.3%	ND
	EtOH≤0.5%	ND
	Acetone≤0.5%	0.10%
	ACN≤0.041%	ND
	EtOAc≤0.5%	0.0003%
	THF≤0.072%	ND
	2-Me THF≤0.072%	ND
	n-Heptane≤0.5%	0.0002%
	Toluene≤0.089	ND
Purity(HPLC)	≥99.5%	99.93%
Conclusion	Conform with enterprise specification

Physical and chemical properties

Density 1.3± 0.1g /cm3
Boiling point 715.0±60.0 °C at 760 mmHg
Molecular formula C25H24N6O2
Molecular weight 440.497
Flash point 386.2±32.9 °C

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What is the difference between ibrutinib and venetoclax?

Ibrutinib and venetoclax are oral cancer drugs that are designed to affect different biochemical pathways. Ibrutinib targets Bruton tyrosine kinase (BTK), an enzyme involved in cell signaling, whereas venetoclax inhibits BCL2 proteins, which are involved in cell survival and growth.

Is Ibrutinib Powder irreversible?

Ibrutinib is an irreversible inhibitor of Bruton tyrosine kinase (BTK) that blocks downstream B-cell receptor activation. Numerous in vitro and in vivo studies confirm the specific activity of ibrutinib against BTK-restricted targets.

What are the benefits of ibrutinib?

It is also used to treat chronic graft-versus-host disease (cGHVD) after one or more lines of treatment did not work. It interferes with the growth of cancer cells, which are eventually destroyed by the body. Ibrutinib is an antineoplastic agent (cancer medicine).

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We adhere to the principle of "customer first, honesty first", and always provide customers with high-quality and efficient products and high-quality services. Choose faithfulness. Choose a healthy life!

With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.

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Transportation Time	Shipping method	Cargo weight requirements	Advantage
3-7 days	DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS	Suitable for under 50kg. International door to door express	We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places.
7-15 days	By Air	Suitable for more than 50kg. fast and cheaper for large order
15-60 days	By Sea	Suitable for more than 500kg. Cheapest shipping way

Send your Inquiry for more details, Click email：sales4@faithfulbio.com

Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.

Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.

Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.

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