Raw Lapatinib Powder CAS 231277-92-2
Product Name:Lapatinib
CAS NO.:231277-92-2
Molecular Formula:C29H26ClFN4O4S
Purity & Grade: 99% HPLC; Medicine grade
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 24 months
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
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Description
What is Lapatinib?
Raw Lapatinib powder is an oral inhibitor of reversible small-molecule tyrosine kinase against HER-1/HER-2. Lapatinib has a different mechanism of action from Herceptin, which can down-regulate cell proliferation signals by double blocking the HER-1/HER-2 pathway. The clinical indication is a combination of capecitabine for HER2 overexpression in advanced or metastatic breast cancer with prior treatment including an anthracycline, taxane, and trastuzumab. The effective rate of first-line monotherapy in the late stage is about 12-24%, while the general clinical guidelines recommend second-line therapy. The effective rate of combined therapy with capecitabine is about 26-33%, and the clinical benefit rate is up to 71.3%, which is also the most commonly used lapatinib combined chemotherapy regimen.
Lapatinib Picture | Lapatinib MF |
Lapatinib powder Benefits
Raw Lapatinib powder is mainly used in:
Lapatinib in combination with capecitabine is indicated for the treatment of advanced or metastatic breast cancer patients with HER2 (ebb-2 overexpression) and prior treatment, including anthracycline, paclitaxel, and trastuzumab. Note: This product must be used in patients with recurrent metastasis who have progressed after trastuzumab treatment. There is no data to support use in off-label populations.
Application of Lapatinib
Lapatinib is a tyrosine kinase inhibitor that effectively inhibits human epidermal growth factor receptor-1 (ErbB1) and human epidermal growth factor receptor-2 (ErbB2) tyrosine kinase activity. It is unique in that it works in a number of ways, preventing breast cancer cells from receiving the signals they need to grow. The mechanism of action is to inhibit the phosphorylation and activation of tumor cells by inhibiting the ATP sites of EGFR(ebb-1) and HER2(ebb-2) and block the down-regulation signal by the homodimer and heterodimer of EGFR(ebb-1) and HER2(ebb-1). Molecular targeted therapy for breast cancer is a pointer to the treatment of oncogenes and their related expression products related to the occurrence and development of breast cancer. Molecular targeted drugs inhibit or kill tumor cells by blocking signal transduction of tumor cells or related cells to control changes in gene expression.
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How To Obtain Samples of Lapatinib?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API powder Lapatinib.
The Best Lapatinib Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Lapatinib?
Faithfulbio specialize in Lapatinib for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
Transportation Time | Shipping method | Cargo weight requirements | Advantage |
3-7 days | DHL,Germany DHL,Germany DPD, | Suitable for under 50kg. | We have warehouses in Germany and California, the USA, |
7-15 days | By Air | Suitable for more than 50kg. | |
15-60 days | By Sea | Suitable for more than 500kg. |
kindly note: Use this compound for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Lapatinib?
Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!
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