Mirabellon is the first one to treat overactive bladder β 3 Adrenaline receptor agonists, whose successful marketing has filled β The blank of adrenoceptor agonists in the treatment of overactive bladder.
Pharmacological action of this product
Mirabellon powder mainly acts on β 3 receptors to relax the bladder detrusor and increase its stability. Three kinds of human detrusor cells and urethral epithelial cells were found β Receptor subtype（ β 1. B2 and β 3)， β The mRNA of 3 receptors is mainly expressed on human urinary smooth muscle cells, accounting for the bladder tissue β 97% of receptor mRNA. β The expression of receptor mRNA and the function of its signal pathway suggest β 3 receptors play a mainstay role in the normal and pathological bladder.
Will Mirabellon cause dysuria?
98% Mirabellon is mainly used to treat overactive bladder in adults, and can also be used to treat symptoms such as urgency and frequency of urination. However, Mirabegron is a prescription drug, which can only be taken after being diagnosed by a doctor. At the same time, the drug should be used according to the dosage required by the doctor, and the drug should not be adjusted by oneself. If Mirabellone is used correctly, the symptoms of dysuria will not appear. However, it may cause damage to the kidney and urinary tract infection during the use of drugs, so it is necessary to use drugs carefully.
In case of overactivity of the bladder, you can see a doctor in time, use other drugs for treatment under the guidance of the doctor, and try not to take YM 178, so as not to affect your body. Patients can take M receptor antagonists, such as tolterodine, trospium chloride, etc., which can improve bladder sensory function. At the same time, calcium channel blockers, such as verapamil and nifedipine, can also be taken to inhibit bladder detrusor contraction.
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