Xi'an Faithful BioTech Co., Ltd. is selling Epitalon Powder CAS 307297-39-8. Please feel free to contact us if you have any purchase needs.
Epitalon Powder CAS 307297-39-8 is a white, powdery solid, a synthetic polypeptide known as the "vitamin of epithelial tissue." Epitalon is an anti-aging agent and telomerase activator, exhibiting inhibitory effects on the development of spontaneous tumors in mice and possessing geroprotective activity.
Send your Inquiry for more details, Click email：sales4@faithfulbio.com
I. Introduction to Epitalon
Epitalon, also known as Epithalon, is a synthetic tetrapeptide. It was first developed by a Russian research team led by Vladimir Khavinson in the 1980s, modeled after the natural peptide epithalamion extracted from the pineal gland. It has attracted wide attention due to its potential anti-aging effects and is extensively studied in the fields of longevity and regenerative medicine.
II. Mechanism of Action and Biological Effects
(I) Core Mechanism Analysis
Epitalon raw powder's biological activity is mainly achieved through three major pathways, with telomerase activation being the most crucial:
Telomere Protection System Regulation: By directly activating telomerase activity and upregulating its gene expression, it promotes telomere DNA sequence elongation, delaying telomere shortening during cell division, thereby inhibiting cell senescence and apoptosis. This mechanism is considered the core of "cellular-level anti-aging" because telomere length has been widely used as a biomarker of cellular age.
Neuroendocrine Regulation: Targeting the hypothalamus-pituitary-gonadal axis (HPG axis), it enhances the hypothalamus's sensitivity to endogenous hormones, normalizes gonadotropin (FSH, LH) and prolactin levels, and simultaneously regulates melatonin synthesis in the pineal gland, repairing circadian rhythm disorders.
Cellular Protection Network Activation: By regulating the levels of inflammatory mediators such as complement C3 components and C-reactive protein, it inhibits acute inflammatory responses; simultaneously, it enhances the function of the antioxidant enzyme system, balances the body's oxidative-antioxidative homeostasis, and reduces lipid peroxidation damage.
(II) Confirmed Biological Effects Preclinical studies and preliminary clinical observations have confirmed that Epitalon powder has multidimensional biological effects:
Anti-aging effects: A 12-month clinical study showed that it can significantly improve metabolic indicators in accelerated aging populations, restoring elevated uric acid, alkaline phosphatase, and cholesterol levels in the elderly to normal and maintaining stability within 10 days, while reducing the incidence of recurrent infections and chronic diseases.
Tumor suppression potential: Animal experiments have shown that it can reduce the incidence of spontaneous breast tumors by inhibiting oncogene expression and regulating the cell proliferation cycle, demonstrating potential cancer prevention value.
Physiological function regulation: It improves peripheral hemodynamics, optimizes blood rheology, and reduces intravascular thrombosis; it also has an inhibitory effect on vaginal epithelial and endometrial hyperplasia in anovulatory women.
Neuroprotective effects: Intranasal administration can enhance neuronal activity and shows repair potential in models of neurodegenerative diseases such as retinitis pigmentosa.
Send your Inquiry for more details, Click email：sales4@faithfulbio.com
III. Quality Control System
Industry Quality Standards and Certification System The global Epitalon raw material industry has established a relatively unified quality control system. Core standards include: Purity grading: Industrial grade ≥95%, research grade ≥98%, pharmaceutical grade ≥99%, with pharmaceutical grade requiring individual impurities ≤0.5%; Safety indicators: Heavy metal content ≤10ppm, total microbial count ≤100CFU/g, endotoxin ≤0.5EU/mg.
IV. Application Areas
Distribution of Core Application Scenarios
The application of Epitalon raw material is currently concentrated in the fields of scientific research and specialty raw materials, mainly divided into four directions:
Scientific Research Field: Used as a core reagent in aging mechanism research (telomere biology, circadian rhythm regulation), oncology research (oncogene inhibition), and neurodegenerative disease research. Globally, research institutions account for approximately 60% of procurement. Typical users include university life science colleges, medical research institutes, and R&D departments of biotechnology companies. In the cosmetics raw material field: Leveraging its cell repair and antioxidant properties, it is used in the formulation development of high-end anti-aging skincare products, focusing on the concepts of "dermal repair" and "rhythm regulation," and requires combination with ingredients such as hyaluronic acid and ceramides.
In the pharmaceutical intermediate field: As a potential precursor to peptide drugs, it is used in the preclinical development of anti-tumor and anti-aging products.
In the special health field: Used in sports medicine for physical recovery research, and in veterinary medicine for the prevention and treatment of age-related diseases in pets; these applications are currently in a niche exploratory stage.
VI. Industry Trends
Technological Development Trends
Production Process Upgrades: Solid-phase synthesis will transition to microwave-assisted synthesis, increasing reaction efficiency by over 30% while reducing solvent consumption; biosynthetic methods (such as enzymatic synthesis) are expected to be industrialized, further improving product purity and reducing production costs.
Precision Quality Control: The introduction of mass spectrometry and capillary electrophoresis will enable precise qualitative and quantitative analysis of trace impurities, driving quality standards towards ultra-high purity levels of "99.5% purity + no unknown impurities."
Formulation Technology Innovation: The development of cyclodextrin inclusion complexation technology and nanoparticle delivery systems will improve the water solubility and skin permeability of the raw powder, expanding its application in the cosmetics field.
1. Do you have a problem whit delivery to my country?
A:We have warehouses in Europe, America and Australia. At the same time, if you are from Europe, the goods can be sent from Germany, and if you are from America or Canada, the goods can be sent from California.
2. How is the goods packed?
A:We usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.
3. When will you sent out the goods after successful payment?
A:Normally the order will be delivery within 3-7 days after the order confirmed, except the customized products.
4. How to proceed order?
A:Please Let me konw the product you are looking for,quantity and the destination country wihch help me to give you a right price;After you confirm all details of order, pay money in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.
Conclusion
Epitalon raw material, a peptide compound with over thirty years of research accumulation, has laid a scientific foundation for the industry's development due to its unique telomerase activation mechanism and multidimensional biological effects. Currently, the industry has formed a market structure with China as the core of production and scientific research as the main driving force, but it faces multiple challenges such as insufficient clinical evidence, inconsistent standards, and regulatory risks. In the future, with the upgrading of production technology, the accumulation of clinical data, and the improvement of the regulatory system, Epitalon raw material is expected to gradually transition from a "scientific research reagent" to a "pharmaceutical raw material" and a "high-end cosmetic ingredient," demonstrating greater value in the fields of anti-aging and cell health. Industry participants need to focus on technological innovation and compliant operation to seize opportunities in this potential market.
As a provider of premium Epitalon Powder CAS 307297-39-8, Xi'an Faithful BioTech Co., Ltd. leverages state-of-the-art production technology and rigorous quality assurance to meet international pharmaceutical requirements. Our dedication to superior quality, cost-effective pricing, and tailored technical support has made us the preferred collaborator for healthcare professionals and researchers worldwide. To obtain detailed specifications and application guidance for our Epitalon Powder, contact our technical team at sales4@faithfulbio.com and explore how our offerings can enhance your product formulations.