Gabapentin Bulk Powder's pH is tested in 10% water solution at 25°C, with acceptable results sitting from 6.5 to 8.0.
This pH reading is one key quality marker for pharma-grade gabapentin API. Formulation teams and bulk buyers check this value to confirm the material keeps stable acid‑base traits. Once readings go beyond this target interval, the API may not mix well with excipients, leading to unexpected problems while making tablets or capsules.
A pH result outside specs often signals unseen quality risks, such as leftover acid or alkali impurities. Faithful Chemical works as a direct manufacturer and bulk supplier. We provide eligible Gabapentin Bulk Powder and full QC paperwork to all our B2B partners.
Basic Properties
Gabapentin carries CAS 60142-96-3, used for research into GABA-related drug products. Its formula is C₉H₁₇NO₂, weighing 171.24 g/mol. A cyclohexane ring forms the core structure, attached with aminomethyl and carboxylic acid side groups. These structural features set most physical and chemical behaviors that lab teams care about when developing drug formulas.
Stored at normal room conditions, the raw material is white crystals that flow easily. It dissolves partially in clean water; you get around 10 mg/mL dissolved at room temperature. This compound has both weak acid carboxyl sites and basic amino groups, making it amphoteric. This unique trait creates its isoelectric point and changes pH once dissolved in water. This mix of acidic and basic groups creates the 6.5–8.0 pH range seen in standard water-based lab tests.
These built-in chemical traits change how the powder behaves during manufacturing. Gabapentin's amphoteric nature means it is sensitive to strong acid or strong base environments. Long exposure to extreme pH can cause slight chemical shifts and raise impurity amounts. Its crystal arrangement controls powder flow, particle size distribution and compression behavior. All these properties are critical for later tablet pressing and capsule filling work.
This Gabapentin Bulk Powder is not ready for oral intake and cannot be taken directly. To create commercial drug products, researchers must create complete formulas mixed with different auxiliary pharmaceutical materials. Teams track solubility, pH response and crystal shape across all production steps. Even tiny changes to these physicochemical traits can mess up formula stability, create uneven batches and reduce end-product quality. That's why all material characteristics go through careful checks during daily quality control work.
Usage & Purchasing Notes
Related Research & Testing Notes
Mix up the water solution only when you are ready for pH testing. If it sits for hours, readings will shift and you cannot trust those data.
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Calibrate the pH instrument with standard buffer liquids ahead of every single test to get reliable numbers.
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Keep the test environment at 25 °C whenever you can. Changes in temperature will shift pH test results.
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Take steps to avoid contaminating your samples. Random impurities mess up pH detection work.
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Record the solution strength and pH numbers you obtain. This practice helps keep your lab records traceable.
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Major Application Directions
| Application scope | Pre-formulation study, solid-state research, analytical validation, solid dosage production |
| Usage restriction | For laboratory & industrial processing only, not for direct human administration |
| Common packing type | Sealed aluminum foil bag, fiber drum |
Key Notes for Purchasing & Handling
Before placing your order, take time to review all quality paperwork
Read through product specifications and batch COA records. Check important values including purity, loss after drying, heavy metal content and related impurities. These documents help validate lab notes and on-site quality checks. Faithful Chemical manufactures and supplies this material in bulk. We provide full quality documentation to all our B2B customers.
Test small sample lots in your lab before committing to bulk purchases
We suggest you run simple trials with sample material first. Your purchasing and research teams may test the powder within your own lab facilities. This step confirms whether the material works well for your R&D or production work. Faithful Chemical supplies samples for B2B partners across the globe.
Follow practical guidance to store and handle the powder properly
Store the powder in cool, dry rooms with good air circulation. Keep it clear of direct sunlight, powerful oxidizing agents and corrosive chemicals. Seal all containers securely to prevent water from entering and degrading the powder. Faithful Chemical packages bulk gabapentin with moisture resistant materials to handle large B2B shipments.
Inspect incoming goods as soon as they reach your site
Start quality testing immediately once shipments arrive. Verify all physical and chemical properties meet agreed requirements prior to starting lab studies or manufacturing work. Faithful Chemical applies strict in-house quality controls. This keeps consistent quality between different batches for our B2B clients.
Questions Buyers Ask Before Placing A Bulk Order
Conclusion and References
Conclusion
Gabapentin Bulk Powder (CAS 60142-96-3) is a GABA analog API commonly used to develop solid oral pharmaceutical products. Thanks to its amphoteric molecular structure, it displays distinct physicochemical features: a pH of 6.5–8.0 for 10% aqueous solution tested at 25°C, medium water solubility, and powder performance governed by its crystal form.
Key physicochemical parameters including pH, particle characteristics, hygroscopicity and crystal state directly influence excipient compatibility, tableting and capsule filling workflows. Researchers should apply standard test methods for pH detection, material characterization and stability assessment. Sealed dry storage is required to avoid water absorption and crystal transformation.
Faithful Chemical acts as an experienced bulk manufacturer and trusted supplier. We offer premium Gabapentin raw powder, batch COA certificates, complete quality files and sample support for worldwide B2B collaborators.
Our Gabapentin Bulk Powder meets international pharmaceutical standards. Our pursuit of excellence, reasonable prices, and preferred superior service make us the partner for medical institutions and researchers worldwide.
If you require Gabapentin Bulk Powder research or production
Please contact Faithful Chemical Click
Email: allen@faithfulbio.com
WhatsApp: +86 13137770562
References
1.United States Pharmacopeia. Gabapentin Monograph, USP-NF.
2.Goa KL, Sorkin EM. Gabapentin: A review of its pharmacological properties and clinical potential in epilepsy. Drugs, 1993, 46(3):409–427.
3.Abualhasan MN, et al. HPLC Analytical Method Development and Validation of Gabapentin. International Journal of Analytical Chemistry, 2022.
4.Acton A, et al. Plasticity in zwitterionic drugs: the bending properties of gabapentin and their hydrates. Acta Crystallographica Section B, 2019.
5.British Pharmacopoeia. Gabapentin Monograph, BP 2024.
6.El-Sayed YM, et al. Pre-formulation characterization and stability assessment of gabapentin solid powder. Journal of Pharmaceutical Sciences, 2015.
7.Kumar S, et al. Hygroscopic behaviour and solid-state stability study of gabapentin API under varied humidity and temperature. Journal of Drug Delivery Science and Technology, 2020.
8.Gennaro AR. Remington: The Science and Practice of Pharmacy, 23rd Edition, Pharmaceutical Press.