What is bromelain?

Apr 19, 2025

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When eating fresh and delicious pineapple, your tongue will feel abraded by sandpaper. If you eat too much pineapple, it may cause pain in your tongue, gums and lips, and even bleeding. Many people may think that it is an allergy, or that the pineapple is immature. In fact, this is a peculiar phenomenon of pineapple. The reason for this situation is a substance called bromelain, which can digest protein, so when you eat pineapple, it will decompose the protein in contact with cells, leading to this cutting pain and even bleeding.

 

What is bromelain?

Bromelain is a sulfhydryl protease extracted from pineapple juice, peel, etc. Pale yellow amorphous powder, slightly smelly, slightly soluble in water, and its enzyme activity is inhibited by heavy metals. The optimum pH value for casein, hemoglobin and BAEE is 6 ~ 8, and that for gelatin is 5.0. According to related research, after contacting with skin, it preferentially hydrolyzes the peptide chains on the carboxyl side of basic amino acids (such as arginine) or aromatic amino acids (such as phenylalanine and tyrosine), selectively hydrolyzes fibrin, and can decompose muscle fibers, but has little effect on fibrinogen.Therefore, it is often used as an enzyme to tenderize meat and decompose protein in food industry ,Also commonly used for beer clarification. In addition, it can also be used as a digestive aid to help digest protein in food. In addition, bromelain is also used in the medical field, which can inhibit inflammation and infection and can be used to treat various inflammatory diseases. At the same time, in some food processing, bromelain powder is used as food additive to improve texture and taste. It should be noted that if you are allergic to bromelain, you should avoid touching or using substances containing this enzyme.

 

Can bromelain prevent cardiovascular and cerebrovascular diseases?

For some patients who gradually gain weight, have obviously high blood lipid levels and have suffered from cardiovascular and cerebrovascular diseases in the near future, doctors will advise them to supplement a natural enzyme preparation called "bromelain" for a long time after prescribing conventional lipid-lowering drugs, in order to further reduce blood viscosity and inflammatory risk, so as to prevent the recurrence of cardiovascular events such as heart disease and stroke.Concept map of bromelain

This is because in relevant medical research, bromelain has shown multiple potential benefits in cardiovascular and cerebrovascular diseases:
1. Anti inflammatory effect: Chronic inflammation is considered as one of the important inducements of atherosclerosis. When the vascular endothelium is continuously stimulated by inflammation, it will promote plaque formation. Bromelain powder helps to inhibit this process by reducing the release of specific inflammatory mediators.
2. Antiplatelet aggregation and fibrinolysis: Thrombosis is an important mechanism leading to myocardial infarction and stroke. When platelets aggregate excessively or there is an excess of fibrin in the blood, it is easy to form blood clots in coronary or cerebral arteries, thereby blocking blood flow. Based on a large amount of clinical data, it has been found that moderate supplementation of high-purity bromelain raw powder can inhibit excessive platelet aggregation and accelerate fibrin degradation, thereby reducing the chance of thrombosis.
3. Improve blood circulation and viscosity: An increase in blood viscosity can cause additional burden on the heart and blood vessels. Pineapple protease helps reduce blood viscosity, making blood flow smoother, thereby reducing the burden on the heart and improving oxygen supply to tissues and organs.
Of course, the current evidence for cardiovascular protection still requires further validation through large-scale, randomized controlled trials. However, for patients with clear cardiovascular disease risk factors, bromelain has gradually been accepted by some clinical experts as a long-term auxiliary health care method, while ensuring safety and no obvious adverse reactions.

 

Can bromelain kill 98% cancer cells?

In laboratory studies, bromelain has shown certain anti-tumor potential. For example, some in vitro experiments have shown that bromelain can inhibit the proliferation of certain cancer cells and induce cancer cell apoptosis. However, most of these studies are in the preliminary stage, mainly conducted in cell culture and animal models, and have not yet been fully validated in large-scale clinical trials. Therefore, the claim that bromelain can kill 98% of cancer cells lacks scientific basis and exaggerates its actual effect. In addition, cancer cells belong to abnormally proliferating cells, and human hair cells have the fastest proliferation, which is similar to cancer cells. If bromelain can kill 98% of cancer cells, theoretically it also has a killing effect on human hair cells, but people who frequently use this product have not experienced abnormal hair loss.

 

Can bromelain treat thyroid diseases?

Thyroid diseases include thyroid nodules, hyperthyroidism or hypothyroidism, etc. The existing treatment methods mainly rely on drug therapy, radioactive iodine therapy, or surgical resection. There is currently no authoritative clinical data to support the research on bromelain powder .Therefore, the claim by some merchants that bromelain can treat thyroid diseases also lacks scientific basis.

 

How to treat the latest cognition of bromelain?

Pineapple protease raw powder, as a natural source of supplementary adjuvant therapy, is considered by some clinical practitioners to contribute to the improvement of cardiovascular prevention strategies due to its potential benefits such as anti-inflammatory effects, inhibition of platelet aggregation, and improvement of blood circulation. There is ample clinical application data indicating that long-term moderate supplementation of products containing bromelain, combined with a healthy lifestyle and necessary medication treatment, may effectively reduce the risk of heart attack and stroke. Although bromelain, as an enzyme with multiple biological activities, has shown certain potential in laboratory research, there is currently insufficient scientific evidence to support its ability to kill 98% of cancer cells or effectively treat thyroid diseases. These exaggerated propaganda are more of rumors than scientific facts. When faced with similar information, the public should maintain rational judgment and choose validated medical methods to ensure their own health.


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