Because Ipriflavone tablets have the effect of inhibiting bone absorption, this drug has a relatively good therapeutic effect when used to treat osteoporosis. Clinical practice shows that this drug really helps many patients to relieve symptoms in time and effectively, and helps patients to alleviate the pain brought by the disease. So it is necessary for patients to learn more about the general knowledge of Ipriflavone tablets, so let's first understand the pharmacological effects of Ipriflavone tablets?
Ipriflavone is a kind of isoflavone derivative, belonging to phytoestrogens. It can directly act on bone, inhibit bone absorption, and act by enhancing estrogen to stimulate thyroid to release calcitonin. Therefore, it has some therapeutic effects of estrogen and calcitonin. Because it is only a physiological metabolic process in the body, it does not have the side effects of both.
A large number of research data confirm that Ipriflavone has the following pharmacological effects:
(1) Promote the proliferation of osteoblasts, promote the formation and mineralization of bone collagen, and increase bone mass;
(2) Reduce the proliferation and differentiation of osteoclast precursor cells, inhibit the activity of osteoclasts, and reduce bone resorption;
(3) It increases the secretion of calcitonin through estrogen-like action, and indirectly produces anti-bone absorption effect. These have also become the main pharmacological basis for the treatment of osteoporosis.
In general, with the increase of age, the bone mineral density (BMD) decreases faster, the risk of brittle fracture increases, and the incidence of vertebral fracture can reach about 21%. The treatment with ipriflavone can reduce the incidence of fracture by 50%. Therefore, ipriflavone has a great role in preventing the occurrence of new fractures in patients with osteoporosis.
How to prevent and treat osteoporosis with ipriflavone?
Ipriflavone can prevent and treat osteoporosis through the following mechanisms:
First, such drugs can directly inhibit bone absorption after application. After the drugs are ingested into the human body, they can directly inhibit the number of osteoclasts and inhibit their activity, thus significantly reducing the osteoclast behavior inside the bone.
Second, such drugs can promote the formation of bone. After the application of these drugs, they can cooperate with estrogen to stimulate the parathyroid gland, and then increase the secretion of parathyroid hormone. At this time, the osteoblasts in the bone can be stimulated to increase their osteogenic behavior, and then the bone mass of the patient will be restored.
These drugs are mainly applicable to postmenopausal and senile osteoporosis patients. After use, it can significantly inhibit the reduction of bone mass, delay the process of osteoporosis, maintain positive calcium balance, and improve the condition of back pain.
The above scheme is for reference only. Please use the specific drugs under the guidance of a professional doctor in combination with your own situation.
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