Lasofoxifene powder is a nonsteroidal selective estrogen receptor modulator (SERM)， Fablyn is used to prevent and treat osteoporosis and alleviate severe vaginal atrophy. At the same time, there is sufficient evidence that this product has an obvious inhibitory effect on breast cancer, and it is expected to become a key drug for the treatment of breast cancer in the future.
What is osteoporosis?
Osteoporosis is a systemic bone disease that is prone to fracture due to the decrease of bone density and bone quality, the destruction of bone microstructure, and the increase of bone fragility due to various reasons. Osteoporosis can be divided into primary and secondary types. Primary osteoporosis can be divided into postmenopausal osteoporosis (type I), senile osteoporosis (type II), and idiopathic osteoporosis (including juvenile type). Postmenopausal osteoporosis usually occurs within 5-10 years after menopause; Senile osteoporosis generally refers to the osteoporosis of the elderly after the age of 70; While idiopathic osteoporosis mainly occurs in adolescents, the etiology is unknown.
What is vaginal atrophy?
Vulva atrophy refers to a group of diseases caused by tissue degeneration, skin pigment loss, and atrophy of female skin and vulva mucosa due to nutritional disorders, mainly involving the labia and clitoris. It is often found in childbearing and elderly women, and rare in young girls. Vulva atrophy can be clinically divided into three types: Senile vulva atrophy, primary vulva atrophy, and atrophic sclerotic lichen. The clinical manifestations were dryness, thinning, shrinkage, and volume reduction of the mucosa of the inner side of the labia major, labia minor, and clitoris; In the primary cases, the labia minora and clitoris disappear completely, the labia majora flattens and the tissues become loose. The course of the disease is chronic, generally without conscious symptoms, occasionally with itching.
What is breast cancer?
Breast cancer is often called pink killer, and its incidence rate ranks first among female malignant tumors, while male breast cancer is rare. With the improvement in medical level, breast cancer has become one of the most effective solid tumors. Breast cancer is a phenomenon that the proliferation of breast epithelial cells is out of control under the action of many carcinogenic factors. In the early stage of the disease, it often shows symptoms such as breast mass, nipple discharge, and axillary lymph node enlargement. In the late stage, it can cause distant metastasis of cancer cells and multiple organ lesions, which directly threaten the life of patients.