Introduction to idra-21 cognitive drugs

Idra-21 Cognitive powder is a positive allosteric regulator of AMPA receptors and a benzothiadiazole derivative. It is a chiral molecule in which (+) - IDRA-21 is the active form.

How did IDRA-21 behave in animal experiments?

In the study of promoting intelligence in animals, IDRA-21 powder significantly improved the ability of learning and memory. In reversing cognitive deficits caused by long-term use of alprazolam or scopolamine, it is about 10-30 times stronger than aniracetam. The most amazing thing is its drug metabolism time: it has been studied to produce sustained effects lasting up to 48 hours after a single administration. Researchers say the mechanism of this effect is likely to be through promoting long-term enhancement between brain synapses.

What is the process of cognitive enhancement drug exploration? How was IDRA-21 born?

In 1990, neuroscientist Eric Kandel discovered a brain chemical called cyclic adenosine monophosphate response element-binding protein (CREB), which is a key factor in memory formation. In 1994, neuroscientists Tim Tully and Jerry Yin adjusted the way CREB works in a fruit fly. When learning new habits, fruit flies with enhanced CREB were 10 times faster than their unchanged counterparts. Later, other researchers got the same results in mice. In 1999, Qian Zhuo, a neuroscientist at Princeton University, created a mouse with more pairs of NR2B genes, which can coordinate the activity of synaptic receptors in the brain. In memory and learning tests, NR2-B enhanced mice performed five times better than unmodified mice. After 2000, many new pharmaceutical companies competed to apply these findings to humans. Both memory pharmaceutical and Helikongshan medical are conducting clinical trials on drugs related to CREB. Another COLTEX pharmaceutical company is developing a brain chemical called ampakine to achieve similar effects through another neural pathway. Among so many research institutions, Jingsi pharmaceutical （Abbreviation: IDRA） has developed IDRA-21 through step-by-step analogy research. At the same time, there are many sister products of this product, which have been eliminated for various reasons.