Product description
Benfotiamine Powder is a fat-soluble derivative of thiamine, a synthetic derivative of vitamin B1, and slightly soluble in water.
Benfotiamine is a water-soluble vitamin, mainly used as an adjunctive treatment for polyneuritis, peripheral neuritis, central nervous system injury, myocarditis, and malnutrition and indigestion.
Apart from water-soluble vitamin B1, Benfotiamine has an open thiazole ring in its structure, which forms physiologically active vitamin B1 through closed-loop action in the body.
Benfotiamine Powder is a liposoluble derivative of thiamine and has a higher bioavailability than thiamine. However, Benfotiamine must be dephosphorylated by alkaline phosphatase to become a liposoluble precursor before it can cross the cell membrane to exert its biological effects. It is mainly used clinically for the treatment of diabetic complications, especially for the treatment and prevention of diabetic retinopathy. After being absorbed into the systemic circulation, Benfotiamine is rapidly metabolized into thiamine without increasing the drug concentration in the brain. At the same time, it generates hippuric acid and is excreted through urine.
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COA
| Item | Standard | Test Results |
| Assay | ≥ 98.0% | 99.30% |
| Appearance | White crystal or white crystalline powder | Complies |
| Identification | Positive | Complies |
| Clarity and color of solution | Clear and colorless | Complies |
| Chloride | ≤0.053% | 0.01% |
| Sulfate | ≤0.011% | 0.00% |
| Heavy metals | ≤ 20ppm | 7ppm |
| Benzoic acid | Not detectable | Complies |
| Thiamine | ≤ 0.1% | 0.05% |
| Loss on drying | ≤ 1.50% | 0.90% |
| Conclusion | Conform with enterprise specification | |
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Density: 1.4±0.1 g/cm ³
Boiling point: 745.1±70.0 °C at 760 mmHg
Melting point: 165 ° C
Molecular formula: C19H23N4O6PS
Molecular weight: 466.448
Flash point: 404.4±35.7 °C
Precise mass: 466.107605
PSA 191.05000
LogP 1.81
What is Benfotiamine Powder used for?
People use benfotiamine for nerve damage caused by diabetes (diabetic neuropathy). It is also used for alcohol use disorder, Alzheimer disease, arthritis, and other conditions, but there is no good scientific evidence to support most of these uses.
What is the difference between vitamin B1 and Benfotiamine Powder?
One of the key differences between thiamine and benfotiamine is their ability to prevent or reverse complications associated with high blood sugar levels. Benfotiamine has been shown to be more effective than thiamine in preventing diabetic complications, such as neuropathy and nephropathy.
Is Benfotiamine Powder natural or synthetic?
Benfotiamine Powder is a synthetic analogue of thiamine with significantly greater bioavailability. Benfotiamine activates transketolase, an enzyme that helps clear AGEs, thus improving postprandial endothelial function.
Five health benefits of Benfotiamine Powder
Compared with natural thiamine, Benfotiamine has a higher absorption rate and offers several benefits to health.
1. Benfotiamine may help optimize thiamine deficiency
Due to its increased bioavailability, Benfotiamine may help reduce symptoms associated with vitamin B1 deficiency.
Benfotiamine may help reduce the risk of chronic eye diseases
There is evidence suggesting that the combination of thiamine and other nutrients may help reduce the risk of cataracts.
3. Benfotiamine will help optimize the symptoms of glucose metabolism disorders
Many patients with glucose metabolism lack thiamine, which is an important cofactor in carbohydrate metabolism.
4. Benfotiamine may help alleviate Alzheimer's disease
The levels and activities of thiamine related to thiamine-dependent enzymes in the tissues and brains of patients with Alzheimer's disease are both decreased.
5. Benfotiamine may help repair kidney diseases
In a study on patients with glucose metabolism accompanied by renal dysfunction, urinary albumin excretion (UAE) was used as a marker of renal function. The research found that the urinary albumin excretion rate of patients who received thiamine repair decreased, while that of patients who received placebo did not decrease significantly.
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why choose us
Our Factory
Package
Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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