what is k2 menatetrenone?
Vitamin K is a class of compounds with quinone structures, including five different structures, namely vitamin K1, K2, K3, K4, and K5. K2 Menatrenone is a series of compounds that are light yellow crystals, mainly synthesized by intestinal bacteria. There are 14 types based on the length of the isoprene side chain on C3, and k2 menatetrenone is mainly used to treat osteoporosis (20). Research has shown that K2 Menatrenone has osteogenic effects, promotes calcium metabolism, and can also inhibit bone resorption caused by osteoclasts, thereby increasing bone density and preventing osteoporosis.
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Product name |
k2 menatetrenone |
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CAS |
863-61-6 |
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Molecular formula |
C31H40O2 | |
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Molecular weight |
444.65 | |
| EINECS | 863-061-6 | |
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Appearance |
light yellow powder |
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| Melting point | 350℃ | |
| Density |
1.0461 (rough estimate) |
What are the functions of k2 menatetrenone?
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k2 menatetrenone plays a crucial role in bone and cardiovascular health, as well as blood clotting. It helps the body absorb calcium, which is essential for strong bones and teeth, and also helps prevent calcium from accumulating in soft tissues like blood vessels. Vitamin K2 activates two proteins, osteocalcin and matrix GLA protein (MGP), which are involved in these processes. |
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What are the symptoms of a lack of k2 menatetrenone?
Human gut bacteria can produce k2 menatetrenone, so there is no risk of deficiency in daily life. However, long-term use of sulfonamide drugs or antibiotics to inhibit bacteria, or any conditions that cause lipid malabsorption such as bile duct obstruction, constipation, tropical diarrhea, pancreatic dysfunction, etc., will all lead to vitamin K deficiency. Minor injuries that are usually harmless can also cause bleeding and death in animals lacking K. Newborns with aseptic intestinal lumen may also experience neonatal hemorrhage due to K deficiency, which can continue until there are bacteria in the intestinal lumen. As long as adults have good absorption of intestinal fat, there is no risk of vitamin K deficiency. It is well known that patients who lack vitamin K have reduced levels of prothrombin in their blood and prolonged clotting time. Therefore, it is believed that the main function of K is to promote the synthesis of prothrombin in the liver. After years of research, it has been found that vitamin K also promotes the production of coagulation factors VII, IX, X, etc. in the liver. When lacking K, these coagulation factors in the blood will decrease.
Product Specification
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Items |
Specifications |
Results |
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Appearance |
yellow crystalline powder |
Conforms |
| Total organic impurities | ≤1.0% | 0.48% |
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Assay |
≥98% |
99.6% |
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Loss on Drying |
≤0.5% |
0.27% |
| Residue on Ignition | ≤0.1% | 0.08% |
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Heavy metal |
≦20ppm |
10ppm |
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E Coli enrichment |
Negative/ 10g |
Absent |
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Salmonella |
Negative/ 10g |
Absent |
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Total Aerobic Plate |
NMT 1000 cfu/g |
Conform |
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Count Yeast and Mold |
NMT 100 cfu/g |
Conform |
Conclusion：Conform with specification and qualified.
What is the mechanism of action of k2 menatetrenone?
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The mechanism of action of k2 menatetrenone is similar to that of vitamin K1, which can assist gamma glutamyl carboxylase in converting glutamic acid (Glu) into gamma carboxylated glutamic acid (Gla). This process is helpful for generating Gla proteins (proteins containing Gla), for example: osteocalcin: bone mineralization GAS6: cell proliferation thrombin, anticoagulant protein: blood homeostasis
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How and where to buy k2 menatetrenone?
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
|
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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