Sodium deoxycholate is the sodium salt of deoxycholic acid, which is a white crystalline powder at room temperature, similar to bile smell and has a strong bitter taste. In the experiment of bile bacteriolysis, bile or bile salt has high surface activity, which can quickly activate autolytic enzyme and accelerate the autolysis of bacteria such as Streptococcus pneumoniae.
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TEST ITEMS |
SPECIFICATIONS |
RESULTS |
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Appearance |
White crystalline powder.It is slightly smelly, bitter and easy to absorb moisture . |
Complies |
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Solubility |
This product is soluble in water or ethanol, but insoluble in ether . |
Complies |
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Identification |
1.Take 10mg of this product, add 1ml of sulfuric acid and 1 drop of formaldehyde to dissolve it, place it for 5 minutes, and then add 5ml of water to form blue-green suspended solids . 2.The infrared absorption spectrum of this product should be consistent with that of the control sample . 3.Identification reaction of sodium salt. |
Complies |
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Clarity of solution |
The solution should be clear and colorless |
Complies |
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Melting point |
350-360℃ |
357℃ |
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Assay |
≥98. 0% |
98.9% |
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pH (2% solution) |
7.5~9.5 |
8.0 |
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Specifies rotation |
+ 40° ~+ 45° |
+ 42° |
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Sodium |
5.0%~6. 1% |
5.4% |
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Loss on drying |
≤5.0% |
3.7% |
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Heavy metal |
≤20 .0ppm |
<20 .0ppm |
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Total plate count |
≤1000cfu/g |
Complies |
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Yeast &Mould |
≤100cfu/g |
Complies |
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E.Coli |
Negative |
Negative |
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Salmonella |
Negative |
Negative |
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Pseudomonas aeruginosa |
Negative |
Negative |
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Staphylococcus aureus |
Negative |
Negative |
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Conclusion:Conform to Enterprise Standard |
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What is the purpose of sodium deoxycholate?
Pure sodium deoxycholate powder is white crystal and easy to absorb moisture. If it is configured as an ionic detergent, it can be easily used for dissolving cells and water-insoluble protein. In addition, sodium deoxycholate is a kind of anion surfactant, which is used as a selective inhibitor of bacterial culture medium and can effectively lyse the interaction between cells, viruses and proteins. In clinical experiments, this product is often used to prepare cell lysates and adipose tissue lysates.
In addition, because of its special structure, this product is also widely used as an absorbent for mucosal and skin administration and a carrier for some drugs. As a pharmaceutical adjuvant, it can promote the transport and absorption of drugs, and form mixed micelles with phospholipids to form a biocompatible carrier, which can significantly improve the solubility of poorly soluble drugs, increase the bioavailability of drugs and reduce the adverse reactions of drugs.
What are the precautions for transportation, storage and use of this product?
Sodium deoxycholate is the sodium salt of deoxycholic acid, which has strong hygroscopicity and strange smell, so it needs to be sealed and stored and transported. The sunlight may make this product turn yellow gradually, so it needs to be stored and transported in the dark. When in use, the pH value is closely related to the solubility of this product. At 15℃, the solubility of deoxycholic acid (free acid form) in water is 0.24 g/L, while the solubility of sodium deoxycholate (sodium salt form) is more than 333 g/L. Therefore, the control of pH value is very important for the use of this product. Precipitation may occur in aqueous solution with pH < 5.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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