Dyclonine Hydrochloride Raw Powder, is a white crystalline powder, Melting point: 175-176°C, molecular formula: C18H28ClNO2, molecular weight: 325.87, slightly smelly, tingling, slightly soluble in water, soluble in ethanol, acetone, chloroform, and 60℃ water. Stable in the air, it will decompose when exposed to heat, the solution will become turbid, and oil will be precipitated at the bottom, and it will be stored in a closed place away from light. The pH of the 1% aqueous solution is 4 ~ 7. It is a local anesthetic with quick effect, long-acting time, little adverse reaction, and high safety.
What is the research background of Dyclonine HCl?
The effectiveness of local anesthetics is related to skin permeability, anesthetic efficacy, duration of action, adverse reactions (such as mydriasis, systemic toxicity, tissue irritation, and allergic reaction), and chemical stability. In 1952, Dyclonine Hydrochloride Raw Powder was developed and applied to clinics in 1956. It has strong penetrating power to a mucous membrane, quick effect, and long-lasting local anesthetic effect, and has achieved good results in tracheal intubation, gastrointestinal endoscopy, fiberoptic bronchoscopy, skin pruritus, premature ejaculation, etc. Other aromatic ketone local anesthetics. The anesthetic depth is strong, the speed is fast, the duration is long, the penetration to the mucous membrane is strong, and the sterilization effect is achieved. Its toxicity is lower than cocaine and benzocaine. It is suitable for topical anesthesia and has analgesic, antipruritic, and antibacterial effects on the skin. Injection anesthesia or infiltration anesthesia is not suitable for local stimulation.
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| Real shot pictures of Dyclonine Hydrochloride powder | Dyclonine Hydrochloride structure diagram |
What are the pharmacological properties of Dyclonine Hydrochloride?
1. There are many ways of administration. Compared with intravenous injection, Dyclonine Hydrochloride is easier to be absorbed into the blood through the mucous membrane and functions through the circulatory system, and the mucous membrane of the throat or respiratory tract absorbs more quickly.
2. The absorption rate is related to the blood supply or blood flow rate, dose, and action time of the affected part.
3. The anesthetic effect of 1%Dyclonine Hydrochloride in oropharyngeal mucosa: it takes effect within 2min, reaches its peak within 4~6min, and the anesthetic intensity decreases after 15min.
4. 1%Dyclonine Hydrochloride is anesthetized on the surface of the larynx, which takes effect within 5 minutes and lasts for 20 ~ 25 minutes.
Where is Dyclonine Hydrochloride used?
1. Endoscopic examination
Dyclonine Hydrochloride Raw Powder can effectively perform surface anesthesia in bronchoscopy, and it can also be used for gastroscopy. The concentration of dyclonine mucilage preparation is 1%.
2. Stomatological surgery
It is necessary to control severe pharyngeal reflex in dental X-ray film.
3. Tracheal intubation
It can obviously reduce the irritation of intubation to the throat and keep the hemodynamic stability of patients.
4. Ophthalmic surgery
1% dyclonine is used for scleral and corneal analgesia.
5. Urology application
It not only has a strong lubricating effect but also can reduce the damage of urethral catheter to mucous membrane. It also has a local anesthetic effect, blocking the nerve endings of the bladder triangle and relieving the discomfort caused by indwelling urethral catheterization.
How to choose more products
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Dyclonine hydrochloride | 536-43-6 |
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Rocuronium bromide | 119302-91-9 |
tiletamine hydrochloride | 14176-50-2 |
Lidocaine | 137-58-6 |
Lidocaine hydrochloride | 73-78-9 |
Procaine | 59-46-1 |
Procaine hydrochloride | 51-05-8 |
Ropivacaine | 84057-95-4 |
Ropivacaine hydrochloride | 132112-35-7 |
Bupivacaine | 2180-92-9 |
Bupivacaine HCl/Bupivacaine hydrochloride | 14252-80-3 |
Levobupivacaine hydrochloride | 27262-48-2 |
Tetracaine | 94-24-6 |
Tetracaine hydrochloride | 136-47-0 |
Benzocaine | 94-09-7 |
benzocaine hcl/Benzocaine hydrochloride | 23239-88-5 |
Mepivacaine | 22801-44-1 |
Mepivacaine hydrochloride | 1722-62-9 |
Dibucaine | 85-79-0 |
Dibucaine hydrochloride | 61-12-1 |
Articaine | 23964-58-1 |
Articaine hydrochloride | 23964-57-0 |
Pramoxine Hydrochloride | 637-58-1 |
Prilocaine | 721-50-6 |
Propitocaine hydrochloride/Prilocaine hcl | 1786-81-8 |
Proparacaine hydrochloride | 5875-06-9 |
Baclofen | 1134-47-0 |
Xylazine | 7361-61-7 |
xylazine hcl/xylazine hydrochloride | 23076-35-9 |
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Transportation Time | Shipping method | Cargo weight requirements | Advantage |
3-7 days | DHL,Germany DHL,Germany DPD, | Suitable for under 50kg. | We have warehouses in Germany and California, the USA, |
7-15 days | By Air | Suitable for more than 50kg. | |
15-60 days | By Sea | Suitable for more than 500kg. |
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.
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