Sodium 4-phenylbutyrate CAS 1716-12-7
Product Name:Sodium 4-phenylbutyrate
Synonym:PBNA;PHENYL N-BUTYRATE SODIUM SALT;4-PHENYLBUTYRATE, NA;4-PHENYLBUTYRIC ACID SODIUM;4-PHENYLBUTYRIC ACID SODIUM SALT;4PBA;4PBA SODIUM
CAS NO.:1716-12-7
EINECS NO.:605-612-7
Molecular Formula:C10H13NaO2
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 5-10 days
Store & Shelf life: Cool & dry place; 24 months
Description
Product description

Sodium 4-phenylbutyrate represents a valuable functional organic substance frequently adopted in life science and biomedical investigations. Boasting steady physical and chemical traits, favorable water solubility and great biological compatibility, it engages in various vital physiological adjustment pathways within organisms and delivers versatile biological effects.
From a cellular perspective, it modulates the activity of histone deacetylase in a targeted manner and alters chromatin epigenetic characteristics. It maintains the balanced state of cell growth, differentiation and death, and restrains irregular cell multiplication and pathological changes, serving as a crucial experimental material for exploring tumor mechanisms and cellular disorders.
Furthermore, it acts as an effective regulator against endoplasmic reticulum stress.
At the metabolic level, Sodium 4-phenylbutyrate participates in the nitrogen metabolism cycle, promoting the metabolic clearance of toxic nitrogenous metabolites through biotransformation, improving metabolic disorders, and maintaining the stability of the body's internal environment. With the continuous development of scientific research, the research boundaries of this compound are constantly expanding. In addition to traditional metabolic mechanisms and epigenetic studies, it is also widely used in cutting-edge fields such as organ fibrosis, nervous system injury repair, and the exploration of tumor targeting mechanisms. With its advantages of multiple targets, low irritation, and high activity, sodium 4-phenylbutyrate has become an indispensable research material in biomedical research, providing a solid research foundation for the mechanistic analysis of various intractable diseases and the discovery of novel intervention targets, and possessing broad prospects for scientific exploration and translational applications.

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COA
| Test Item | Specification | Result |
| Description | Off-whitecrystalline powder | Conform |
| Assay | ≥99% | 99.50% |
| Water | ≤1.0% | 0.35% |
| Conclusion | Conform with enterprise specification | |
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Density 1.095 g/cm³
Boiling point 290.7ºC at 760 mmHg
Melting point 207 °C (dec.)(lit.)
Molecular formula C10H11NaO₂
Molecular weight 186.183
Flash point 187.9ºC
Exact mass 186.065674
PSA 40.13000
LogP 0.75920
Mechanism of action of Sodium 4-phenylbutyrate
Epigenetic Regulation: Inhibits histone deacetylases, adjusts chromatin state, controls cell growth, differentiation, and apoptosis, and inhibits abnormal cell proliferation.
Relieves Endoplasmic Reticulum Stress: Reduces cell damage caused by unfolded protein accumulation, weakens inflammatory responses, and protects various functional cells such as nerve cells and liver cells.
Regulates Internal Metabolic Cycles: Participates in nitrogen metabolism, accelerates the decomposition and excretion of harmful nitrogenous metabolites, and maintains a stable internal metabolic environment.
Cellular Protection and Repair: Reduces pathological cell loss, decreases cell death, and provides protection against related diseases in tissues and organs.
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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FAQ
01. What is the core epigenetic function of sodium 4-phenylbutyrate?
It can inhibit the activity of histone deacetylases, remodel the epigenetic state of chromatin, regulate the balance of cell growth, differentiation, and apoptosis, and inhibit abnormal cell proliferation.
02. In which research areas is sodium 4-phenylbutyrate currently mainly used?
Sodium 4-phenylbutyrate is mainly used for research on the mechanisms of neurodegenerative diseases, liver injury, organ fibrosis, abnormal cell proliferation, and tumors.
03. Where can I buy Sodium 4-phenylbutyrate?
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