Lansoprazole is a substituted benzimidazole derivative and the second proton pump inhibitor. It has obvious inhibitory effect on basic gastric acid secretion or gastric acid secretion caused by all irritants. Pure lansoprazole powder is beige crystal with melting point of 178 ~ 182℃. It usually acts on the last ring of gastric acid secretion, strongly inhibiting gastric acid, and has obvious therapeutic effect on duodenal ulcer, reflux esophagitis and other symptoms.
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Items |
Standard |
Result |
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Appearance |
A white to off-white colour powder |
Complies |
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Dentificatio
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A: IR conforms to standard Max. B:UV at 285nm |
Up to standard Up to standard |
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Water |
≤0.1% |
0.08% |
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[Related substances]Lansopra zole sulfone |
≤0.4% |
0.2% |
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Lansoprazole N-oxide Lansoprazole sulfide |
≤0.1% ≤0.1% |
0.08% Not detected |
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Other individual impurity |
≤0.1% |
0.03% |
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Total impurities |
≤0.6% |
0.3% |
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Residue on ignition |
≤0.1% |
0.03% |
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Assay |
98.0%-102.0% |
99.45% |
| Conclusion: | The results conform to the Ph.Eur. standard. |
What is the difference between Lansoprazole and Omeprazole?
Omeprazole and lansoprazole belong to the same class of drugs, that is, both are proton pump inhibitors. However, lansoprazole is an upgraded product of omeprazole, which means omeprazole belongs to the first generation of proton pump inhibitors, while lansoprazole belongs to the second generation of proton pump inhibitors. So Lansoprazole powder has better functionality and fewer side effects. The specific situation is as follows:
1：Their chemical structures are different.Lansoprazole is a benzimidazole compound, while omeprazole belongs to benzenesulfonamide compound.
2：Their mechanisms of action are different.Although the basic principle of action of the two products is the same, both can alleviate related symptoms and treat related diseases by inhibiting gastric acid secretion, the specific details are different. Lansoprazole mainly reduces gastric acid secretion by blocking the proton pump function on parietal cells. Omeprazole achieves the same effect by blocking the activation site of the same protein.
3.Their drug metabolism is different.Lansoprazole tablets are a new type of proton pump inhibitor drug that can improve the bioavailability of drugs by serving atomic structures. Omeprazole enteric coated tablets are the first generation proton pump inhibitors, which can generally inhibit the activity of sodium potassium ATPase after being complexed with linolenic acid, thereby improving the bioavailability of drugs. There is no superiority or inferiority in the different drug metabolism of the two.
4.The duration of drug efficacy varies.Due to their different pharmacokinetic characteristics, the duration of efficacy of lansoprazole and omeprazole also varies. Generally speaking, omeprazole has a longer duration than lansoprazole, thus providing a longer protective effect. But the effect of Lansoprazole tablets is more pronounced than omeprazole.
5.Lansoprazole can delay the metabolism and excretion of epileptic products such as phenytoin sodium. Omeprazole will affect the absorption of iron and slow down the metabolism of dicoumarin, warfarin and other drugs.
To sum up, although both lansoprazole and omeprazole are used to treat gastrointestinal diseases, due to their differences, it is necessary to consider the individual situation and follow the doctor's advice when choosing the appropriate drugs.Our company can provide low-priced lansoprazole and omeprazole for your research and comparison. If you have relevant purchasing plans, please contact us by email:sales6@faithfulbio.com
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| Lansoprazole 103577-45-3 | 73590-58-6 Omeprazole |
Can't lansoprazole be stopped once it is used?
Lansoprazole powder has a good effect on inhibiting gastric acid secretion, which can reduce the damage of gastric acid to digestive system. Lansoprazole is often used to treat digestive system diseases, such as duodenal ulcer and gastric ulcer, and can also be used to treat reflux esophagitis. Its action time is longer, and its side effects are less, so it belongs to clinical standing products. However, it should be noted that if the illness is mild, the body will basically recover after a few days of use, and the drug can generally be stopped according to the doctor's advice. If the degree of illness is serious, it will not have a good therapeutic effect after a few days of use, and the medication time usually needs to be extended, and the state of the body needs to be paid close attention to during the medication period. Patients should not stop taking drugs privately, let alone suddenly, which is very likely to lead to the recurrence of gastric ulcer. Because the proton pump inhibitor in the drug will be gradually metabolized with the metabolism and blood circulation of the human body, when the drug is suddenly stopped, the efficacy of the proton pump inhibitor will disappear and the secretion of gastric acid will increase, thus causing the recurrence of gastric ulcer or expanding the area of the original gastric ulcer, causing abdominal pain, acid reflux, belching, anorexia and other symptoms. The usual method is to gradually stop taking drugs under the guidance of a doctor.
What are the side effects of lansoprazole?
1. Allergy. Some people are allergic to lansoprazole because of their own physical problems. After application, allergic reactions may occur, manifested as skin rashes, and even dyspnea due to laryngeal edema.
2, gastrointestinal irritation symptoms. Occasionally, there will be symptoms such as diarrhea, constipation and nausea, which are caused by drugs stimulating gastrointestinal mucosa.
3. Symptoms of nervous system. Lansoprazole may irritate the nervous system, resulting in headache, dizziness, drowsiness and other symptoms.
In addition to the above common side effects, there may be side effects such as cytopenia, fever and elevated uric acid. If it is serious, you should go to the hospital in time and adjust the treatment plan under the guidance of a doctor.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide low-priced lansoprazole and omeprazole for your research and comparison. If you have relevant purchasing plans, please contact us
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
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