What is Glucosamine HCL?
Glucosamine hydrochloride is a natural product. D-Glucosamine hcl is an amino sugar and the precursor of hexosamine biosynthesis pathway, which can lead to the formation of UDP-GlcNAc, and then it can be used to prepare glycosaminoglycans, proteoglycans and glycolipids. Glucosamine hcl inhibits co-aggregation of Candida yeast strain and bacterial strain Streptococcus salivarius. It can be used as a standard to quantify and express chitin content with glucosamine equivalent. Stimulate cells with glucose in the presence of glucosamine.
Glucosamine HCL powder is a white crystalline powder, odorless, slightly sweet, soluble in water, slightly soluble in alcohol, almost insoluble in ether, and soluble in organic solvents such as methanol, ethanol and DMSO. Stable at normal temperature and neutral conditions. It has important physiological functions for human body, participates in detoxification of liver and kidney, plays the role of anti-inflammation, protecting liver and tonifying kidney, and has good curative effect on rheumatoid arthritis and gastric ulcer. It is the main raw material for synthesizing antibiotics and anticancer drugs, and can also be used in food, cosmetics and feed additives.
| Product name | Glucosamine HCL |
| CAS | 66-84-2 |
| Molecular formula | C6H14ClNO5 |
| Molecular weight | 215.63 |
| EINECS Number | 200-638-1 |
| Storage condition | 2-8°C |
| Melting point | 190-194 °C (dec.)(lit.) |
| Solubility | The solubility in water is 0.1 g/mL, clear and colorless. |
| Appearance | white powder |
| Specific rotation | 72.5 º (c=2, H2O, 5hrs.) |
| Water Solubility | soluble |
What is the pharmacological action of Glucosamine HCL?
Glucosamine HCL is an amino monosaccharide existing in the body, especially in articular cartilage, and it is an important component necessary for the synthesis of proteoglycan in human articular cartilage matrix. It selectively acts on articular cartilage, blocks the pathological process of articular cartilage, stimulates chondrocytes to produce glycoprotein with normal polymer structure, inhibits the activities of enzymes that damage cartilage, such as collagen and phospholipase A2, and inhibits the generation of superoxide free radicals that damage cells, prevents the damage of cortical hormones and some non-steroidal anti-inflammatory drugs to chondrocytes and reduces the release of endotoxin factors that damage cells. Through the above ways, Glucosamine HCL powder has a direct anti-inflammatory effect, which can relieve the pain symptoms of bone joints, improve joint function and prevent the development of osteoarthritis.
Product Specification
| Item | Specification | Results |
| Appearance | White Powder | Complies |
| Identification | Positive | Complies |
| Assay | 98% | 98.50% |
| Ash | ≤5.0% | 2.55% |
| Loss on drying | ≤5.0% | 1.20% |
| Ignition residue | ≤2.0% | 0.25% |
| Heavy metals | ≤10ppm | Complies |
| Pb | ≤2.0ppm | Complies |
| As | ≤2.0ppm | Complies |
| Odor | Characteristic | Complies |
| Particle size | 100%through 80 mesh | Complies |
| Microbioiogical: | ||
| Total of bacteria | ≤1000cfu/g | 100cfu/g |
| Fungi | ≤100cfu/g | Complies |
| Salmgosella | Negative | Complies |
| Coli | Negative | Complies |
| Conclusion | Conform with USP/FCC/E302 specification | |
Where is Glucosamine HCL used?
1. Glucosamine HCL powder can be made into products for treating rheumatoid arthritis, ulcer and enteritis, and it is a nutritional additive for food and cosmetics and a culture medium for biochemical cells.
2. Glucosamine HCL, extracted from natural chitin, is a marine biological preparation, which can promote the synthesis of human mucopolysaccharides, improve the viscosity of synovial fluid and improve the metabolism of articular cartilage; Has the function of promoting the injection efficiency of antibiotics, and is used for synthesizing a water-soluble anticancer drug, namely chlorurea, which has the anticancer property of nitrosourea compounds, and has the characteristics of less inhibition of bone marrow toxicity, and shows certain curative effects on melanoma, lung cancer, kidney cancer and the like; Supplementing glucosamine culture medium can enhance the N- glycosylation of secreted proteins and affect cell line variation such as ring cells and stem cells. Glucosamine, an amino sugar, is the precursor of hexosamine biosynthesis route, which can lead to the formation of UDP-N- acetylglucosamine (UDP-GlcNAc), which is subsequently used for.
3. Biochemical research. Glucosamine HCL is extracted from natural chitin, which is a marine biological preparation and the main component of chondroitin sulfate.
HTML5 atlas of Glucosamine HCL
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Which is better glucosamine sulfate or glucosamine hydrochloride?
Glucosamine HCL and glucosamine sulfate are both good products for the treatment of osteoarthritis. They can improve the metabolism of soft tissue and bone and promote the repair of cartilage cells. They are commonly used drugs for the treatment of osteoarthritis. In terms of efficacy, the two products are actually similar, but one is hydrochloride and the other is sulfate. Glucosamine HCL contains a large amount of chloride ions, which has a certain irritation to the gastrointestinal tract. Therefore, if you use Glucosamine HCL, it is recommended to take it half an hour after a meal. It will be safer.
In the long run, Glucosamine HCL contains chloride ions, which has a certain burden on liver and kidney function. If it is used in large quantities for a long time, liver and kidney function should be monitored. However, compared with glucosamine sulfate, Glucosamine HCL has a much higher purity and is more stable than glucosamine sulfate. This is its advantage. So each has its pros and cons. When choosing, make a choice based on your own situation.
What are the precautions of Glucosamine HCL Powder?
1 Use with caution in patients with severe liver and kidney dysfunction;
2 If symptoms do not improve after one course of treatment, please consult a physician or pharmacist;
3 Use with caution in pregnant and lactating women;
4 Do not use if you are allergic to this product, and use with caution if you have allergic constitution;
5 Do not use this product if its properties change;
6 Keep this product out of reach of children;
How and where to buy Glucosamine HCL Powder wholesale?
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure, or prevent any disease.
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