Ribothymidine CAS 1463-10-1
Product Name:Ribothymidine powder;Ribothymidine
CAS NO.:1463-10-1
Molecular Formula:C10H14N2O6
Purity & Grade: 99% HPLC; Medicine grade
MOQ & Package: 10g; Package according to demand
Shipping: Safe and fast delivery
Store & Shelf life: Cool & dry place; 24 months
Lead Time: 1-3 days
Warehouse: USA and Germany warehouse
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Description
Product Introduction
5-Methyluridine (Ribothymidine, Ribosylthymine, Thymine riboside) is a pyrimidine nucleoside and an endogenous metabolite in humans. 5-Methyluridine plays a very important role in the field of life sciences. Its unique chemical structure can form hydrogen bonds with other hydrogen bond donor materials such as water. 5-Methyluridine contains both hydrophobic and hydrophilic groups, so it is not miscible with water in any proportion.
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| Ribothymidine Picture | Ribothymidine MF |
Product Application
Ribothymidine is mainly used as a biochemical synthesis reagent and a basic raw material for pharmaceutical chemistry. It is an important intermediate for antiviral drugs such as zidovudine, stavudine and alovudine.
Synthetic RNA oligos exhibit purity decreasing as a function of length, because the efficiency of the total synthesis is the numerical product of the individual step efficiencies, typically below 98%. Analytical methods for RNAs up to the 60 nucleotides (nt) have been reported, but they fall short for purity evaluation of 100nt long, used as single guide RNA (sgRNA) in CRISPR technology, and promoted as pharmaceuticals. In an attempt to exploit a single HPLC method and obtain both identity as well as purity.
Here we report that IP-RP is less suitable compared to the conventional ion-exchange (IEX) for analysis of 100nt RNAs. We demonstrate the relative stability of RNA in the denaturing/basic IEX mobile phase, lay out a protocol to determine the on-the-column stability of any RNA, and establish the applicability of this method for quality testing of sgRNA, tRNA, and mRNA. Unless well resolving HPLC methods are used for batch-to-batch evaluation of man-made RNAs, process development will remain shortsighted, and observed off-target effects in-vitro or in-vivo may be partially related to low purity and the presence of shorter sequences.
Product Specification
| Item | Specification | Test Results |
| Appearance | White powder | Conform |
| Identification | TLC:Standard solution and test solution same spot,RF | Conform |
| Assay (Dry Basis) | 98.0%~100.5% | 99% |
| Specific Optical | -2.4°~ -2.8° | -2.71° |
| PH | 4.5~7.0 | 5.3 |
| Heavy Metals (As Pb) | ≤10ppm | <10ppm |
| As | ≤1ppm | Not Detected |
| Pb | ≤0.5ppm | Not Detected |
| Cd | ≤1ppm | Not Detected |
| Hg | ≤0.1ppm | Not Detected |
| Related substance | Spot not bigger than standard | No spot |
| solution spot | ||
| Residual solvent | <0.5% | Complies |
| Water Content | <2% | 0.18% |
| Conclusion：Conform with enterprise specification . | ||
How To Obtain Samples Ribothymidine?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Ribothymidine.
The Best Ribothymidine Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Ribothymidine?
Faithfulbio specialize in Ribothymidine for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use Ribothymidine for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Ribothymidine?
Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!
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