Product description

Cinchonine, is a quinoline-type alkaloid, a kind of Cinchonine alkaloid, also known as cinchonine, weak Cinchonine alkaloid, a stereoisomer of cinchonidine. Cinchonine is an alkaloid in Cinchonine bark with more content besides quinine. Cinchonine and its derivatives are widely used in preparation, separation and analysis of chiral drugs and chiral intermediates.
Cinchonine Powder is an organic compound that contains one cyanide group and one carbon group. Its structure can be expressed as RNC, where R stands for any organic group.
Cinchonine has a pungent odor and to many people has a particular bad smell. It is usually a colorless liquid, but may appear yellow or brown in high concentrations.
Cinchonine is widely used in the field of organic synthesis. It can be used as a reactant to participate in many important organic reactions, such as isomerization reaction, synthesis of carboxylate and so on. Cinchonine can also be used as a chemical agent, such as a catalyst for ammonia synthesis and a ligand for organometallic reactions.
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COA
| Items | Standard | Result |
| Appearance | White crystalline or granular powder | Conform |
| Solublity | Slightly soluble in chloroform,sparingly soluble in Alcohol, and practically insoluble in water. |
Conform |
| Specific rotation | Between +219° to +229° | 220.81° |
| Loss on drying | NMT 1.0% | 0.74% |
| Melting point | Between 255.0 to 261.0°C | 256.9°C |
| Assay | NLT 99.0% of C19H22N20 calculated on the dried basis | 99.79% |
| Purity (By HPLC) | 87.20% | |
| Residual solvent byGC a. Toluene b. Benzene |
a. Max 100ppm b. Max 2ppm |
0.00ppm 0.00ppm |
| Conclusion | Qualified. | |
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What does cinchonine do?
Cinchonine Powder and cinchonidine are extracted from the bark of cinchona. The anti-malarial effects of these drugs have been proven and are used clinically to treat Plasmodium falciparum.
What is the difference between quinine and cinchonine?
Cinchonidine and quinine are similar alkaloids. The difference is only that cinchonidine has H while quinine has OCH3 in the same position. By epimerization and NADPH activity, cinchonine and quinine are synthesized from cinchoninone.
Is cinchonine antimalarial?
The Cinchona bark contains alkaloids like quinine, quinidine, cinchonine and cinchonidine. These agents are effective antimalarial drugs and have been used clinically in malaria caused by Plasmodium falciparum.
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
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