Product description

NADP sodium salt powder CAS 1184-16-3 is a crucial nucleotide coenzyme. It is a phosphorylated derivative of the 2'-position of the ribosome linked to adenine in nicotinamide adenine dinucleotide (NAD+), participating in various anabolic reactions such as the synthesis of lipids, fatty acids, and nucleotides. These reactions require NADPH, the reduced form of NADP+, as a reducing agent and hydrogen negative donor.
β-Nicotinamide adenine dinucleotide phosphate sodium salt (NADP), formerly known as pyridine triphosphate (TPN), co-dehydrogenase II, or oxidized coenzyme II, is a substance composed of nicotinamide adenine dinucleotide and a phosphate molecule linked by an ester bond. It is widely used in industrial production as a common enzyme catalyst. Most NADP products currently on the market are of low purity. Low-purity NADP affects industrial catalytic performance, and impurities in low-purity NADP can also be introduced into the process conversion reaction, increasing the difficulty of downstream products and thus raising the cost of separation and purification. Obtaining high-purity NADP requires multiple purification steps, but traditional multi-step NADP purification methods have low recovery rates and generate large amounts of wastewater. Currently, commonly used separation methods involve ion exchange resins or macroporous resins for purification, but these methods also generate large amounts of wastewater, and wastewater treatment increases costs, making them unsuitable for large-scale production.

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COA
| Tests | Specifications | Results |
| Appearance | White to yellowish powder | conform |
| Purity (HPLC) | ≥98% | 99.90% |
| Assay of NAD (enzym) (calc.on dry basis) | ≥97% | 99.10% |
| Sodium content (IC) | ≤ 1% | 0.09% |
| Water content (KF) | ≤ 5% | 2.69% |
| PH value in water (100mg/ml) | 2.0-4.0 | 2.27 |
| Methanol (By GC) | ≤ 1% | 0.02% |
| Ethanol (By GC) | ≤ 2% | 0.00% |
| Heavy metal content (AAS) | ||
| Pb | ≤ 0.5 ppm | N.D |
| As | ≤ 0.5 ppm | N.D |
| Hg | ≤ 0.5 ppm | N.D |
| Cd | ≤ 0.5 ppm | N.D |
| Total microbial count (GB 4789.2) | ≤750 CFU/g | 7 CFU/g |
| Coliform (GB 4738.3) | < 3MPN/g | N.D |
| Conclusion | Conform with enterprise specification | |
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Chemical Stability of NADP Sodium Salt
NADP sodium salt is an important biochemical reagent widely used in scientific research and medicine due to its crucial role in cell metabolism and signal transduction. It is essentially a sodium phosphate salt, exhibiting relatively good chemical stability and generally not prone to decomposition reactions. Although its chemical stability is good, care must be taken to avoid the influence of oxidizing agents and acidic substances during use to maintain its activity and effectiveness.
Biological Activities of NADP sodium salt powder CAS 1184-16-3
NADP sodium salt exhibits diverse biological activities. It can form a coenzyme redox pair (NAD+, NADH) with β-reduced nicotinamide adenine dinucleotide (NADH), thereby participating in a wide range of enzymatically catalyzed redox reactions. Furthermore, in redox reactions, NADP sodium salt/NADH serves as the ADP-nuclease unit donor in ADP ribosylation (ADP-ribosyltransferase; poly(ADP-nuclease) polymerase) reactions. The biological nature of NADP sodium salt is nicotinamide adenine dinucleotide phosphate (NADP), a coenzyme that supports electron transfer redox reactions in many applications, especially anaerobic reactions in lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme pair in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system.
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3-7 days |
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Suitable for under 50kg. |
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15-60 days |
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Suitable for more than 500kg. |
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FAQ
01. What are the storage requirements for NADP sodium salt powder CAS 1184-16-3? What is its shelf life?
Solid NADP sodium salt must be stored in a sealed, moisture-proof, and light-protected container; it can be stored for more than 2 years at -20℃, 6 months at 2~8℃, and only 1 month at room temperature (25℃); aqueous solutions should be prepared and used immediately, and can be stored for 1 week at 2~8℃, or 3 months after repackaging at -20℃.
02. What are the main application areas of NADP sodium salt powder CAS 1184-16-3?
Core applications include biochemical research (enzyme activity detection, metabolic pathway research), diagnostic reagents, biopharmaceuticals, the food industry (fermentation metabolic regulation), and biotechnology (cell culture, synthetic biology).
03. Where can I buy NADP sodium salt powder CAS 1184-16-3?
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