What is Maraviroc?
Maraviroc is a white powder that has a very effective effect on AIDS. It is a CCR5 receptor antagonist developed by Pfizer and is also the earliest approved HIV entry inhibition raw material. Maraviroc API Raw Material combines and alters the structure of the CCR5 receptor on human immune cells, preventing R5 subtype viruses from attaching and penetrating cells, thereby inhibiting the proliferation of viral infections. It only works on R5-tropic strains.
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What is the mechanism of action of Maraviroc?
Maraviroc is an entry inhibitor, acting as a negative allosteric regulator of the CCR5 receptor on human cell surfaces. Its function can be understood as keeping the virus outside the cells. For HIV to enter immune cells, in addition to binding to the CD4 receptor, it usually needs to also grasp an auxiliary receptor called CCR5 to complete the invasion. The Maraviroc API Raw Material does exactly this - it pre-attaches to this CCR5 receptor, effectively seizing the "handle" that the virus needs to grasp. As a result, even if the virus manages to attach to the cell through the CD4 receptor, it cannot actually get into the cell interior. It should be noted that this product is only effective against virus strains that rely on the CCR5 receptor for entry; if the virus switches to using another receptor called CXCR4, it will lose its effectiveness.
What are the advantages of Maraviroc?
The greatest advantage of Maraviroc lies in its unique mechanism for combating viruses. When this product fights against viruses, it will take the lead in occupying the CCR5 receptors on the surface of immune cells. For the virus to enter, it must seize this "handle". One of the benefits of this approach is that it often works even for viruses that have become resistant to several other products. This was also observed in clinical trials. For those very severe patients, when Maraviroc API Raw Material was added, the effect of virus interference became even more pronounced.
Another advantage is its relative mildness. Many products for combating HIV cause heavy liver burden or increase blood lipids over time, but Maraviroc poses no obvious risk to the heart.
Another benefit is its strong applicability for specific groups. For instance, for those who already have cardiovascular diseases or are simultaneously infected with tuberculosis or hepatitis B, using this product would be safer.
MF of Maraviroc
| CAS | 376348-65-1 |
| Molecular formula | C29H41F2N5O |
| Molecular weight | 513.68 |
| EINECS | 609-456-0 |
| Melting point | 79-81°C |
| Acidity coefficient | 7.3(at 25℃) |
| Density | 1.29±0.1 g/cm3 |
Specification
| Item | Specification | Result |
| Appearance | White powder | Complies |
| Heavy metal | ≤0.002% | Complies |
| Total impurity | <2.0% | 0.76% |
| Single impurity | ≤1.0% | 0.67% |
| Assay | ≥98.0% | 99.20% |
| Conclusion | Conform with enterprise specification | |
A variety of shipping methods for you to choose
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Maraviroc API Raw Material etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
FAQ:
Q1: What are our markets?
With superior quality and competitive price, our products not only are sold well in China, but also exported to Europe, North America, Southeast Asia, the Middle East and South Africa.
Q2: If I don't know how to use product, can you give me an instruction?
Yes, you can send email to get product label and instruction. We have professional agricultural expert working in our company and supply the application information and offer solving solution.
Q3:Can I get free sample?
If you're manufacturer or distributor in the same field with us. Welcome to request a sample. Sample is free, but express freight will be in your account. When you place order in the future, previous sample and express freight will be deducted from the cost of the order.
Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.
If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received, please contact us by Email ：sales6@faithfulbio.com . Our team is committed to ensuring the complete satisfaction of customers.
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