Clorsulon API CAS 60200-06-8
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Clorsulon API CAS 60200-06-8

Name: China Clorsulon API CAS 60200-06-8 Suppliers, Manufacturers, Factory - Wholesale Price - Faithful Biotech
Brand: Faithful
SKU: 304510111

Product Name:Clorsulon
Synonym:4-amino-6-(trichloroethenyl)-3-benzenedisulfonamide;curatrem;keluosuolong;l631529;4-AMINO-6-(TRICHLORO-ETHENYL)-1,3-BENZENEDISULFONAMIDE;4-AMINO-6-TRICHLOROVINYL-1,3-BENZENEDISULFONAMIDE
CAS NO.:60200-06-8
EINECS NO.:262-100-2
Molecular Formula:C8H8Cl3N3O4S2
Purity & Grade: 99%; Medicine grade
Character:White powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 5-10 days
Store & Shelf life: Cool & dry place; 24 months

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Description

At ambient conditions, Clorsulon API is a white or faint grey crystalline powder. It features outstanding physicochemical stability, resisting deliquescence and breakdown during regular warehousing, and counts as a conventional sulfonamide fine chemical for livestock production. Its mode of action centers on restraining parasitic carbonic anhydrase: hindering carbohydrate metabolism and energy production cripples parasite physiological activity step by step. Such pharmacological trait grants it strong activity against liver flukes of Fasciola genus, turning it into a vital antiparasitic raw material for industrial cattle and sheep breeding.

In terms of application scenarios, Clorsulon API is primarily tailored to the livestock breeding industry-specifically for ruminants such as cattle and sheep. It acts effectively not only against mature flukes within the host but also demonstrates excellent inhibitory effects against immature flukes that have not yet fully developed; consequently, it is frequently utilized in pasture-based grazing systems. Beyond its primary application in livestock management, this substance is also widely employed in scientific research settings to investigate the enzymatic mechanisms of parasites.

Test Item	Specification	Result
Description	White to off white powder	White powder
Solubility	Slightly soluble in water,freely soluble	Complies
	n acetonitrile and in methanol,very
	slightly soluble in methylene chloride
Identification	A)The IR spectrum is concordant with	Complies
	reference spectrum of clorsulon USP RS	Complies
	B)The chromatogram of the Assay	Complies
	preparation obtained as directed in the	Complies
	Assay exhibits a major peak for	Complies
	clorsulon,the retention time of which	Complies
	corresponds to that of the Standard	Complies
	preparation obtained as directed in the assay	Complies
Melting Range	Between 197℃ to 203℃	198℃ to 200℃
Loss on Drying	Not more than 0.5%w/w	0.21%w/w
Residue on lgnition	Not more than 0.1%w/w	0.06%w/w
Organic impurities	Analysis 1:The chromatogram shows	Complies
	principal spot at the same Re value	Not detected
	Analysis 2:Anyindividual	Not detected
	mpurities:(NMT 0.5%);no spot other than	Not detected
	the principal spot of the Sample solution is	Not detected
	arger or more intense than that of the	Not detected
	principal spot of the 5-uL portion of	Not detected
	Standard solution B	Not detected
	Total impurities:Not more than 2.0%	Not detected
Residual solvent test	Methanol:Not more than 3000 ppm	22 ppm
Assay(By HPLC)	98.0%to 101.0%On dried basis	99.13%
Conclusion	Conform with enterprise specification

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Density 1.8±0.1 g/cm³
Boiling Point 651.7±65.0 °C at 760 mmHg
Melting Point 194–203 °C
Molecular Formula C₈H₈Cl₃N₃O₄S₂
Molecular Weight 380.656
Flash Point 348.0±34.3 °C
Exact Mass 378.902191
PSA 163.10000
LogP 1.04

Targeting the Glycolysis Pathway: Severing Energy Supply
Specifically targets the unique energy metabolic pathways of *Fasciola hepatica*, inhibiting key glycolytic enzymes within the parasite to block glucose metabolism, thereby depleting the organism's energy reserves and rendering it unable to survive.
Competitively Inhibiting Multiple Key Glycolytic Enzymes
Acting as a competitive inhibitor, it targets enzymes such as phosphoglycerate kinase and phosphoglycerate mutase, thereby disrupting the normal progression of glycolysis.
Inhibiting Parasite ATP Production and Lowering Energy Levels
Significantly reduces ATP levels within the fluke, disrupting the organism's energy homeostasis and leading to the loss of essential functions related to motility, metabolism, and reproduction.

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Clorsulon API

Transportation Time	Shipping method	Cargo weight requirements	Advantage
3-7 days	DHL,Germany DHL,Germany DPD, UPS,USPS,FedEx,TNT,EMS	Suitable for under 50kg. International door to door express	We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places.
7-15 days	By Air	Suitable for more than 50kg. fast and cheaper for large order
15-60 days	By Sea	Suitable for more than 500kg. Cheapest shipping way

Its primary target species are beef cattle, dairy cattle, and sheep. It is principally used to treat fascioliasis (liver fluke infection) and is frequently formulated in combination with ivermectin to simultaneously eliminate flukes, nematodes, and ectoparasites.

Animals with mild infections generally exhibit no abnormalities. However, cattle with severe liver fluke infections may experience transient lethargy, reduced appetite, or mild abdominal pain following treatment. These symptoms are the result of an inflammatory reaction within the biliary tract triggered by the mass die-off of parasites and typically resolve spontaneously.

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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.

Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.

Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.

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