Product description
Ketorolac tromethamine powder CAS 74103-07-4 effectively inhibits prostaglandin (PG) synthesis, exhibiting analgesic, anti-inflammatory, antipyretic, and platelet aggregation-inhibiting effects. It stimulates insulin secretion, increasing cellular glucose uptake and utilization, thereby lowering blood sugar levels. Simultaneously, it inhibits hepatic glycogenase activity, reducing hepatic glucose synthesis and further lowering blood sugar levels. Furthermore, ketorolac tromethamine lowers blood lipid levels, reducing triglyceride and cholesterol synthesis, thus treating hyperlipidemia.
Ketorolac tromethamine is a synthetic pyridine cyclic carboxylic acid derivative with anti-inflammatory, analgesic, and antipyretic activities. As a non-selective COX inhibitor, ketorolac tromethamine, despite its advantages of being non-addictive and non-dependent, has numerous contraindications due to its significant impact on the cardiovascular system, platelet inhibition, and potential kidney damage, requiring careful clinical attention.
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COA
| Tests | Specifications | Results |
| Appearance | White powder | confirm |
| Identification | ABCin Pass | confirm |
| Solubility | Very soluble in water,soluble in Alcohol; insoluble in Ether and Benzene |
confirm |
| USP Reference standards |
USPTetracaine Hydrochloride RS. USP Endotoxin RS. |
confirm |
| Melting point | 145~150 degree | 146.0~147.5 degree |
| Chromatographic purity |
In Pass | confirm |
| Related substance | Not more than the reference solution 0.05% | confirm |
| Heayy metals | ≤10ppm | confirm |
| PH | 4.5-6.5 | 5.8 |
| Residue on ignition | ≤0.10% | 0.05% |
| Loss on Drying | ≤0.5% | 0.19% |
| Assay | 98.0-101.0% | 99.9% |
| Conclusion | Conform with enterprise specification | |
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Boiling point 493.2ºC at 760 mmHg
Melting point 160-161ºC
Molecular formula C19H24N2O6
Molecular weight 376.404
Flash point 252.1ºC
Exact mass 376.163422
PSA 146.01000
LogP 0.65210
Pharmacological Mechanism of Action of Ketorolac tromethamine powder CAS 74103-07-4:
Core Target: Inhibition of cyclooxygenases (COX-1/COX-2), blocking prostaglandin (PG) biosynthesis, reducing pain, inflammation, and fever signals.
Active Characteristics: The S-isomer is the main active form, exhibiting strong analgesic effects, while its anti-inflammatory and antipyretic effects are relatively weak.
Advantages: No respiratory depression, sedation, addictiveness, or tolerance; can be used as a partial substitute for acute, severe pain.
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why choose us
Our Factory
Package
Shipping Methods
|
Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places. |
|
7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
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FAQ
01. What type of pain is Ketorolac tromethamine powder CAS 74103-07-4 primarily used for?
Acute moderate to severe pain, such as postoperative pain, traumatic pain, renal colic, toothache, etc.
02. Is Ketorolac tromethamine powder CAS 74103-07-4 a complex?
Yes, it is a salt formed from ketorolac and tromethamine in a 1:1 ratio, and has better water solubility.
03. Where can I buy Ketorolac tromethamine powder CAS 74103-07-4?
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