Product Introduction
Losartan potassium powder is a new type of non-peptide angiotensin II receptor (AT1) antagonist. The EXP3174 produced by metabolism in the body is more active and lasts longer than the parent drug. The half-lives of losartan and EXP3174 are 2.2 hours and 6.7 hours, respectively. Losartan potassium has good antihypertensive effects and protects the heart, kidneys, and brain, reverses myocardial and vascular wall hypertrophy, excretes sodium and promotes diuresis, and promotes uric acid excretion. The incidence of adverse reactions is low and patients tolerate it well.
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| Losartan potassium powder Picture | Losartan potassium powder MF |
Product Application
The currently known effects of Losartan potassium powder are as follows:
1. Treating essential hypertension, it can be used alone or in combination with other antihypertensive drugs (such as diuretics).
2. Treating heart failure, it can be used alone or in combination with cardiotonic drugs and diuretics.
3. Preventing stroke in patients with hypertension and left ventricular hypertrophy.
4. Used to slow down the progression of renal disease in patients with type 2 diabetes accompanied by renal disease and hypertension.
Reacting 2-n-butyl- 4-chloro l H-imidazole 5-carboxaldehyde with N- (triphenylmethyl)-5-[ 4'-(bromomethyl) biphenyl-2-yl)] tetrazole in a biphasic solvent system comprising water and an organic solvent in the presence of a base and a phase transfer catalyst at ambient temperature to reflux temperature of the solvent for sufficient time to form an intermediate;
Distilling the solution to remove water as an azeotrope, till water content in the mixture is reduced below 0. 1 % to allow crystallization of losartan potassium in polymorphic form I; h) Cooling the mixture to ambient temperature and isolating losartan potassium polymo ph 1 by filtration
Product Specification
| Test | Specification | Result |
| Description | off-white powder | Conforms |
| Solubility | Easily soluble in anhydrous ethanol and methanol; slightly soluble in acetone; | Conforms |
| Identify | The infrared absorption spectrum of the sample should be consistent with the reference substance spectrum. | Consistent with reference standard spectrum |
| Identification reaction of chloride in absolute ethanol solution of this product | Positive reaction | |
| Loss On Drying | No More Than 0.5% | 0.06% |
| Sulfated ash | No More Than 0.1% | 0.04% |
| Relative substance | Impurity B ≤ 0.15% | Not detected |
| Impurity E ≤ 0.05% | Not detected | |
| Unknown single impurity≤ 0.10% | 0.04% | |
| Total impurities | 0.10% | |
| Residue Solvents (GC) | Isopropyl alcohol ≤ 5000ppm | 212ppm |
| Ethyl acetate ≤ 5000ppm | 245pmm | |
| Chloroform ≤ 60ppm | Not detected | |
| Assay(HPLC) | No Less Than 98.5% | 99.64% |
| (On The Dried Basis) | ||
| Conclusion | Conform with the enterprise standard | |
How To Obtain Samples Losartan potassium powder?
Welcome to send an inquiry to sunny@faithfulbio.com at any time for a free sample if you need the API Losartan potassium powder.
The Best Losartan potassium powder Manufacturer And Supplier
Faithfulbio has rich experience in exporting raw materials and has established stable and long-term cooperative relations with our customers. We always put product quality and service first. If you have raw material purchasing needs, please contact us. We can confirm the order with you according to your purchase quantity. We also support our first cooperation starting from samples. In addition, our fast and safe transportation also enables you to Eliminate the trouble of customs clearance.
We have confidence in the quality of our products, but if there are any after-sales problems, we will respond as soon as possible and solve them with you in the best way.
Why Choose Faithfulbio Losartan potassium powder?
Faithfulbio specialize in Losartan potassium powder for several years, we supply products at a competitive price, and our product is of the highest quality, because we are very strict in product production and testing, and have a complete and mature system. In addition, our employees The quotation for the product is very competitive.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
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15-60 days |
By Sea |
Suitable for more than 500kg. |
kindly note: Use Losartan potassium powder for research purposes only. All compounds have risks. Please consult your doctor and learn about available studies before use. In addition, the above description of the compound comes from online literature. If there is any infringement, please contact us to delete it.
Where To Buy Losartan potassium powder?
Just send an email to sunny@faithfulbio.com, or submit your requirement in the bottom form, we are of service at any time!
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