Xi'an Faithful BioTech Co., Ltd.:a trustworthy supplier of Erdafitinib raw powder
Xi'an Faithful BioTech Co., Ltd. is an export-oriented biotechnology and fine-chemical supplier based in Xi'an, China. Since 2018, we have focused on pharmaceutical intermediates, API powders, plant extracts, and health-industry raw materials for B2B buyers in Europe, North America, Southeast Asia, and the Middle East. For customers sourcing Erdafitinib Raw Powder (CAS 1346242-81-6), our advantage is not "the cheapest price",but a combination of documentation, batch consistency, export experience, and responsive service.
Product Introduction
Erdafitinib Raw Powder is a small molecule compound related to FGFR-targeted research. Erdafitinib targets fibroblast growth factor receptors. It often appears in studies on FGFR mutations and targeted cancer therapy. We mainly provide it in powder and capsule forms, and it's commonly used in drug research and development.
Erdafitinib Raw Powder Mechanism of Action and Biological Activity
Erdafitinib is a potent, orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) family. It works by competitively blocking the tyrosine kinase activity of FGFR1, FGFR2, FGFR3, and FGFR4.
Target Inhibition Activity (IC₅₀): The half-maximal inhibitory concentrations for FGFR1/2/3/4 are 1.2, 2.5, 3.0, and 5.7 nM, respectively, showing high potency at low nanomolar levels.
Selectivity: It has weaker inhibitory activity against the closely related VEGFR2 kinase (IC₅₀ 36.8 nM), showing functional selectivity for the FGFR family.
Anti-tumor Effect: It can inhibit the proliferation of FGFR-expressing cells in vitro; in vivo models show dose-dependent anti-tumor activity and modulation of FGFR and downstream signaling pathways within tumors.
Specifications
| Item |
Specification |
Result |
|
Appearance |
Yellow solid |
Conforms |
|
NMR |
Conforms to structure | Conforms |
| Infrared Spectrum | Conforms to structure | Conforms |
|
Assay |
≥98.5% |
99.4% |
|
Conclusion |
Conform with enterprise specification | |
Applications
Erdafitinib Raw Powder is mainly used in:
Pharmaceutical research and development
FGFR-related research
Cancer biology and targeted therapy research
Drug formulation and development studies
Laboratory research involving kinase inhibitors
Product Advantages
Stable supply for research and development needs.
Clear product identification and batch information.
COA&HPLC&MSDS can be provided for quality checking.
Suitable for laboratory and pharmaceutical research.
Flexible quantities available depending on stock.
Professional export service and international shipping support.
Production Process
Erdafitinib is made through several controlled organic synthesis steps. The process involves key quinazoline and pyrazole intermediates, which go through coupling reactions, and then the desired side chains are introduced through further substitution and amination steps. These steps produce a crude product, which still needs to go through additional steps like purification and refining to remove impurities. The final powder is then dried, tested, and packaged for shipment.
Click email：sales8@faithfulbio.comOr WhatsApp：+86 17782789477
Why Choose Xi'an Faithful BioTech Co., Ltd.?
1.Reliable Supply
We work with stable supply channels and can arrange products according to different quantity requirements.
2.Quality Documents
COA and related product documents can be provided for customers to check before ordering.
3.Flexible Orders
Small trial quantities are available when stock permits. Larger quantities can also be discussed according to the customer's requirements.
4.Export Experience
We have experience handling chemical raw material orders for overseas customers and can help arrange suitable shipping solutions.
5.Fast Communication
We keep communication simple and direct, from quotation and document confirmation to shipment.
6.After-Sales Support
We follow the order after shipment and help customers with shipping documents and delivery updates.
FAQ
Q1: Can you provide a COA?
A1: Yes. A COA can be provided for customers to check the product quality and batch information.
Q2: Do you have Erdafitinib Raw Powder in stock?
A2: Stock depends on the current batch and quantity. Please contact us with your required quantity and we will check it for you.
Q3: Can you arrange international shipping?
A3: Yes. We can help arrange international shipping according to the destination, quantity and local customs requirements.
Contact Us
If you are looking for a reliable supplier of Erdafitinib Raw Powder, please contact Xi'an Faithful BioTech Co., Ltd. for the latest price, COA and availability.
Click email：sales8@faithfulbio.com Or WhatsApp：+86 17782789477
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