SLU-PP-915 Capsules
Faithful chemical stable supply of bulk Erdafitinib API Raw Material,It is a small molecule organic compound, The appearance of pharmaceutical-grade tinib raw material is "pale yellow to yellow solid powder", and its water solubility is poor. Laboratory research shows that it is almost insoluble in pure water, but it can be dissolved in some organic solvents.
It can inhibit four receptor subtypes of FGFR1, FGFR2, FGFR3 and FGFR4 at the same time, which is the core feature that distinguishes it from other FGFR targeted products.
SLU-PP-915 Capsules Description
1. High purity and controllable impurities.
The purity of HPLC is ≥99%, and heavy metals, related substances and residual solvents are strictly controlled; The product batches are stable, and each batch is accompanied by confirmation documents such as COA.
2.Physical and chemical properties and solubility
It appears as yellow solid powder; Insoluble in water, soluble in organic solvents, with good solubility in some organic solvents; Formulation development, in vivo experiment and research of convenient preparation.
3.Good storage stability
Low temperature sealed and protected from light, the validity period can reach 3 years; It is not easy to degrade in powder state, and the transportation loss is low after sub-packaging, so it is suitable for long-term storage or small batch and multiple experiments.
Certificate of Analysis
|
Items |
Specification |
Results |
|
Appearance |
Yellow solid |
Conforms |
|
NMR |
Conforms to structure |
Conforms |
|
Infrared Spectrum |
Conforms to structure |
Conforms |
|
Assay |
≥98.5% |
99.4% |
| Conclusion：Confirm with enterprise specification. | ||
If you want more information of Erdafitinib API Raw Material , pls click here：sales7@faithfulbio.com or Whats APP: 86 17791967496
Products advantages
what is the adavantages of Erdafitinib API Raw Material
inhibit tumor cell proliferation and induce cancer cell apoptosis.
Erdafitinib API Raw Material is a pan-FGFR tyrosine kinase inhibitor. When tumor cells mutate, fuse or expand, these receptors are like stuck switches, constantly sending out proliferation signals, activating downstream pathways and promoting tumor growth and spread. As a space-occupying blocker, his molecules seize the energy binding site on the receptor, cut off abnormal signal transmission .
It is aimed at various subtypes of inhibitors
It is different from inhibitors that only target a single subtype, and it can act on multiple types at the same time, covering more types of gene mutations. Erdafitinib is only effective on FGFR susceptible tumors, and it is targeted to target cells.
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production process
The production process of Erdafitinib API Raw Material starts from quinoline intermediates and goes through key organic reactions such as condensation, cyclization, halogenation, substitution and salification in turn, and gradually constructs the target molecular skeleton to obtain the crude product. After decoloration, recrystallization, centrifugation, drying and other refining processes, the crude product was finally packaged and released after passing all quality inspections such as HPLC and XRD.
SLU-PP-915 Capsules leading supplier in China
Send your inquiry about quantity requirements, packaging, delivery arrangements of erdafitinib to us
Applications of erdafitinib
1. Study on pharmacological mechanism
Erdafitinib API Raw Material is often used to study FGFR target pathway and verify the inhibitory effect on RAS/MAPK and PI3K/AKT pathway.
2. Cell experiment in vitro
It is used to carry out proliferation, apoptosis and invasion tests of tumor cells and evaluate the tumor inhibitory activity of FGFR mutation.
3. Evaluation of animal efficacy in vivo
It is used to construct a tumor-bearing model and to study the anti-tumor efficacy and pharmacokinetics in vivo.
4. Formulation development
As the raw material of API, it is used to study the dissolution, stability and oral administration prescription screening of preparations.
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why choose buy SLU-PP-915 Capsules from Faithful Chemical?
Core strengths
Choose Faithful Chemical that suits you best.
1. Stable crystal form:
Faithful chemical supplies bulk Erdafitinib API Raw Material,There is no risk of polymorph, which saves the screening time and research and development cost of preparation customers;
3. Flexible batch delivery:
Gram-level research and development samples, 10-gram-level clinical batches and kilogram-level commercial batches can all be supplied;
2. Low impurity level:
The purification process is optimized directionally, and the control of genotoxic impurities and process impurities is better than the limited threshold;
4. Green process:
Optimize the solvent system, reduce the use of highly toxic solvents, and improve the three wastes treatment plan to meet the global environmental protection standards;
Supplier quality Assurance
Certificates
As a compliant supplier of SLU-PP-915 Capsules, Faithful chemical is registered in the customs and strictly ensures that each batch of products meets the requirements of Pharmacopoeia.
Contact us for:
✓ Batch-specific COA , HPLC and NMR
✓ Packaging, delivery arrangements
✓ Price policy
Email: sales7@faithfulbio.com
Whats APP: 86 17791967496
FDA Certificate
CQC Certificate
ISO Certificate
gMP Certificate
IQNET Certificate
factory and lab
Faithful Chemical Industry is an enterprise integrating industry and trade, and is based on its own factory.
Relying on location and industrial support, we will integrate domestic compliant factories and large-scale laboratory resources for a long time.
At Faithful Chemical, you can enjoy one-stop purchasing service from research and development to delivery.
Package and shipping
We use professional packaging scheme: inner sterile bag, middle double-layer aluminum foil bag, outer anti-collision express box, and multi-layer protection to ensure strict concealment.
We have established a stable transportation network covering Australia, North America, Europe, the Middle East, Southeast Asia and Africa, and set up dedicated air transport channels for some areas to ensure safe and reliable routes. After the goods are sent out, the whole process is dynamically tracked, and the logistics status is synchronized in real time, so that you can keep abreast of the transportation progress at any time.
Team building and cooperation
Faithful chemical always puts quality first. Over the years, it has served tens of thousands of customers and gained wide recognition. We pursue long-term and stable partnership, and rely on strict quality control system and competitive prices to reduce customer procurement costs.
Faithful Chemical is one of the most reliable API powder manufacturers and suppliers in China. We have rich experience in foreign trade, both in transportation and service. We warmly welcome you to wholesale bulk SLU-PP-915 Capsules from our factory. We have high-quality products and competitive prices.
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Attention:
It cannot be used for the diagnosis, treatment, radical cure or prevention of any disease. This compound is only for scientific research purposes, and direct use is strictly prohibited. Please consult a professional doctor and consult relevant research literature before use
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