Methoxyethoxymethyl Chloride CAS 3970-21-6

2-Methoxyethoxymethyl chloride Introduction

Methoxyethoxymethyl chloride is a transparent, colorless to yellow liquid, CAS: 3970-21-6, molecular formula: C4H9ClO2, molecular weight: 124.57, EINECS: 223-589-8. This product is a synthetic chemical with no natural source. Its main applications are in pharmaceutical intermediates, organic synthesis, fine chemicals, and materials. Its core application is as a pharmaceutical intermediate. 

What is the mechanism of action of 2-Methoxyethoxymethyl chloride?

Methoxyethoxymethyl chloride is a commonly used raw material in chemical synthesis, primarily used as a hydroxyl protecting agent and synthetic intermediate. It can combine with active groups such as hydroxyl groups in the substrate to form another substance, temporarily blocking highly active sites and effectively avoiding various side reactions during the synthesis process. The resulting substance also possesses chelating properties, binding metal ions and acting as a stereoguide in organometallic reactions, precisely controlling the spatial configuration of the product. This protecting group can be directionally removed under specific acidic conditions without damaging other acid-sensitive structures within the molecule. Due to these advantages, 2-Methoxyethoxymethyl chloride is widely used in the preparation of macrocyclic lactones such as Roxithromycin, and is also frequently used in the synthesis of YST-Cyclo (CDFIM) and Ribonucleic acid to protect specific hydroxyl and base groups.

What are the advantages of 2-methoxyethoxymethyl chloride?

Compared to traditional MOM protecting groups, 2-Methoxyethoxymethyl chloride exhibits superior reactivity. It requires milder protection conditions, is simpler to operate, and produces compounds that are resistant to various synthetic environments and exhibit greater stability. Furthermore, it can be efficiently and precisely removed under mild conditions using lactoobionic acids such as Zinc bromide, CERIUM(III) CHLORIDE, and Magnesium bromide.

The ethylene glycol chain in the molecule endows it with unique chelating capabilities, a characteristic not possessed by most similar protecting groups. In addition to its protective functional group, Methoxyethoxymethyl chloride can also act as a stereodirecting group, controlling the spatial structure of chemical bonds in organometallic reactions, playing a prominent role in the synthesis of complex natural products such as paplitaxel analogs.

MF of 2-Methoxyethoxymethyl chloride

CAS	3970-21-6
Molecular formula	C4H9ClO2
Molecular weight	124.57
EINECS	223-589-8
Melting point	200-202 °C
Density	1.091 g/mL at 25 °C
Boiling point	50-52 °C/13 mmHg

Click email：sales6@faithfulbio.com Or WhatsApp：+86 17782780648

A variety of shipping methods for you to choose

Our strengths:

Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide Azathioprine API Powder etc. at a more favorable price. If you are interested, please leave a message. 
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.

FAQ: 

Q1:Why does 2-Methoxyethoxymethyl chloride have a unique advantage in stereoselective synthesis?
Because the substance it generates has chelating ability and can coordinate with metal ions, it acts as a stereodirecting group in organometallic reactions, helping to precisely control the three-dimensional spatial structure of the final product.
Q2: What are the precautions for using 2-Methoxyethoxymethyl chloride? 
It must be carried out in a well-ventilated environment. Operators must wear appropriate protective gloves, protective clothing and goggles, and keep away from fire sources.
Q3:What are the development prospects of 2-Methoxyethoxymethyl chloride?

Methoxyethoxymethyl chloride can be used as a raw material to prepare novel ionic liquids, which can help improve the performance of perovskite solar cells. It is also being gradually applied in the research and development of functional polymer materials.

Disclaimer: The information published on this website comes from the internet, which does not mean that this website agrees with its views or confirms the authenticity of the content. Please pay attention to distinguish it. In addition, the products provided by our company are only used for scientific research. We are not responsible for the consequences of any improper use.

If you are interested in our products, or have critical suggestions on our articles or are not completely satisfied with the products received,

Click email：sales6@faithfulbio.comOr WhatsApp：+86 17782780648

Hot Tags: methoxyethoxymethyl chloride cas 3970-21-6, China, suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, pure, producer, discount, for sale, in stock, free sample, raw powder, raw material, made in China