Pregnenolone is a steroid compound, which is produced by human body through a series of complex biosynthesis processes using cholesterol. The results show that micronized pregnenolone powder is a colorless needle-like crystal, which is insoluble in water, but soluble in organic solvents such as ethanol. At present, the process of synthesizing pregnenolone from conventional industrial flowers is too complicated and inconvenient, with too many one-time synthesis processes, insufficient crystal purity, poor quality of pregnenolone and low efficiency of pregnenolone synthesis. Our company adopts the gas replacement method. Under the effect of Raney nickel, high-standard crystals and 98% purity Pregnenolone raw material can be obtained in the efficient synthesis process
| structural formula |
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Item |
Specification |
Results |
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Appearance |
White to white-like powder |
Conforms |
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Identification |
Colorless or yellowish of the solution |
Conforms |
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Melting point 180℃ to 190℃ with decomposition |
188℃ |
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IR: Corresponds with that of CRS standard |
Conforms |
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PH |
5.8 - 6.5 |
6.08 |
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Chloride |
≤0.02% |
<0.02% |
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Loss on drying |
≤5% |
<3.58% |
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Sulphated ash |
≤0.10% |
0.05% |
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Related substances |
The content of 16-Dehydro Pregnenolone Acetate Impurity 1≤ 1.0% |
0.49% |
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Sum of all the byproducts is Maximum ≤2.0% |
0.81% |
|
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Total Plate Count |
<1000 CFU/G |
≤11.85 CFU/G |
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Yeasts & Moulds |
<100 CFU/G |
≤.2.58 CFU/G |
|
E.Coli |
Negative (In 10g) |
Negative |
|
Salmonella |
Negative (In 25g) |
Negative |
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Assay |
98.0%- 101.0% |
99.42% |
| Conclusion: |
Conform with enterprise specification . |
What are the biological activities of Micronized Pregnenolone Powder?
Micronized Pregnenolone Powder has a very high transformation ability in organisms, which can be further transformed into estrogen Progesterone, progesterone,Finasteride and other essential hormones, which are the key substances to maintain the endocrine balance and various physiological functions of the human body. Of course, if the content of pregnenolone in the body is unbalanced, it will have a bad influence on the health of the body, so it is necessary to obtain high-quality pregnenolone from the outside to supplement the body. After years of research, this product has the following good effects:
1. Neuroprotective effect: In recent years, hot-sale pregnenolone has attracted much attention in the field of neuroscience. Studies have shown that pregnenolone can cross the blood-brain barrier, combine with receptors on neurons and glial cells, and regulate the release of various neurotransmitters and signal transduction. It can protect neurons from oxidative stress, inflammatory reaction and apoptosis, thus playing a neuroprotective role. This is of great significance for the prevention and treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
2. Antioxidant and anti-inflammatory: 5-pregnenolone also showed strong antioxidant and anti-inflammatory activities. It can eliminate free radicals in the body and reduce the damage of oxidative stress to cells; At the same time, it can also inhibit the release of inflammatory factors and reduce inflammatory reaction. These functions help to protect the organs of the body from oxidation and inflammation, and maintain the health and stability of the body.
3. Endocrine regulation: In the endocrine system, DELTA5-PREGNENOLONE is used as a precursor to synthesize important hormones such as progesterone and adrenocortical hormone. These hormones play a key role in regulating human metabolism, stress response and immune function. Therefore, pregnenolone is of great significance for maintaining endocrine balance and various physiological functions of human body.
What are the latest studies on Micronized Pregnenolone Powder?
Pregnenolone, like progesterone, belongs to neurosteroids, and its content is high in some areas of the brain, which researchers speculate is also the main active area for the synthesis of pregnenolone. We know that neurosteroids affect synaptic function, have neuroprotective effects and promote myelination. Pregnenolone and its sulfate can improve cognitive and memory functions, and it is very likely to have a preventive effect on schizophrenia. In animal experiments, pregnenolone participates in the natural negative feedback loop against CB 1 receptor activation in animals. It prevents some irritating products from fully activating CB 1 receptors. According to the latest research, DELTA5-PREGNENOLONE powder can induce tubule polymerization in neuron culture and increase neurite growth in PC12 cells treated with nerve growth factor. And this product can also control the formation and stability of microtubules in neurons, which may affect the neural development during fetal development and the neural plasticity during aging. In addition, pregnenolone sulfate can activate the transient receptor potential M3 (TRPM3) ion channel in hepatocytes and islets, thus causing the influx of calcium ions, and then releasing insulin.
What is the future market development of Micronized Pregnenolone Powder?
Micronized Pregnenolone Powder is considered to be related to the occurrence and development of many diseases, such as Alzheimer's disease, Parkinson's disease and depression. Although the research on its therapeutic effect is still in the primary stage, the preliminary study shows that pregnenolone may have a positive effect on relieving the symptoms of these diseases and improving the quality of life of patients. In addition, 5-pregnenolone powder can also be used for the treatment of rheumatoid arthritis, menopausal symptoms, osteoporosis and other diseases.
A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
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3-7 days |
DHL,Germany DHL,Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Our strengths:
Our company has passed FDA and ISO19001 quality management system certification. And we have internal cooperation agreements with multiple factories and laboratories in China,Our company can provide micronized pregnenolone powder etc. at a more favorable price. If you are interested, please leave a message.
We not only have unique advantages in transportation, but also support multiple payment methods, whether you use US dollars, euros, Australian dollars, or local currencies from Singapore, Malaysia, Thailand, and so on. We can also support local currencies in these regions and countries. In addition, we also support bank cards (credit cards, etc.) for payments.
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