What is fludarabin ?
Fludarabine is a chemotherapy drug commonly used to treat various types of leukemia and lymphoma. It acts on leukemia cells through different pathways, preventing their growth and reproduction, thereby achieving therapeutic effects. It can block the process of DNA synthesis, promote cell apoptosis, and increase chemotherapy sensitivity. In addition, Fludarabine can also be used in combination with other chemotherapy drugs to enhance the therapeutic effect
| Product name | Fludarabine |
| CAS | 21679-14-1 |
| Molecular formula | C10H12FN5O4 |
| Molecular weight | 265-268°C |
| EINECS Number | 244-525-5 |
| Storage condition | 2-8°C |
| melting point | 265-268°C |
| Solubility | NA |
| Appearance | white |
| Boiling point | 747.3±70.0 °C(Predicted) |
| Density | 2.17±0.1 g/cm3(Predicted) |
Product Specification
| Items | Specification | Results |
| Assay | 99%~ 101% | 99.50% |
| Appearance: | White Powder | Complies |
| Odor & taste: | Characteristic | Complies |
| Loss on drying %: | ≤6.0% | 3.83% |
| Heavy metals ppm: | < 10ppm | Complies |
| As | ≤ 3.0 ppm | Complies |
| Pb | ≤ 3.0 ppm | Complies |
| Cd | ≤ 0.5 ppm | Complies |
| Total Plate Count: | < 1000cfu/g | 326cfu/g |
| Yeast & Mold: | < 100cfu/g | 28cfu/g |
| E.Coli: | Negative | Complies |
| S. Aureus: | Negative | Complies |
| Salmonella: | Negative | Complies |
Conclusion：Conform with enterprise specification .
Where is fludarabin usually used?
Fludarabine is a purine analogue that blocks the proliferation and growth of leukemia cells by inhibiting the synthesis of DNA and RNA. It mainly works by inhibiting the activity of DNA polymerase and nucleotide reductase, leading to apoptosis and death of leukemia cells. In addition, Fludarabine is often used as part of the treatment plan for acute lymphoblastic leukemia (ALL) and can be combined with other chemotherapy drugs to improve treatment efficacy.
What are the effects of fludarabin ?
Fludarabine has a significant cytotoxic effect on lymphoma cells by interfering with DNA synthesis and regulating the STAT1 signaling pathway.
The mechanism of action of Fludarabine mainly includes the following aspects:
1. Interference with DNA synthesis, Fludarabine can inhibit DNA synthesis, leading to cell cycle arrest and apoptosis;
2. Regulating the STAT1 signaling pathway, Fludarabine can inhibit the activation of the STAT1 signaling pathway, thereby affecting the growth and differentiation of lymphoma cells
If specific medication plans or side effect management recommendations are needed, it is recommended to follow the guidance of an oncologist.
How and where to buy fludarabin wholesale?
Our products undergo experimental testing and are recognized by customers
You can trust our order because we have a good record of selling legal educational drugs.
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A variety of shipping methods for you to choose
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Transportation Time |
Shipping method |
Cargo weight requirements |
Advantage |
|
3-7 days |
DHL, Germany DHL, Germany DPD, |
Suitable for under 50kg. |
We have warehouses in Germany and California, USA, |
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7-15 days |
By Air |
Suitable for more than 50kg. |
|
|
15-60 days |
By Sea |
Suitable for more than 500kg. |
Send your Inquiry for more details, Click email：sales2@faithfulbio.com Now.
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Note: This compound is only used for laboratory research purposes. The US authorities have not evaluated these claims. Before use, please consult your doctor and learn about available research. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.
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