GS-441524 99.9% Powder is an RNA-dependent RNA polymerase (RdRp) inhibitor, which can play an antiviral role by inhibiting viral nucleic acid synthesis. It is a small molecule nucleoside analog, which mainly interferes with the transcription process of viral RNA, shows strong anti-virus activity against many RNA viruses, and can inhibit the replication of many different types of RNA.
GS-441524 99.9% Powder is phosphorylated into nucleoside monophosphate by cytokines in cells. Then it is transformed into active triphosphate metabolites (NTP structural drugs). In viral RNA synthesis, active NPT structural analogs act as competitors of natural nucleoside triphosphate and compete with natural nucleoside to participate in RNA transcription.
GS-441524 obviously relieved the disease development at least during the medication period, and the safety of GS441524 during the treatment was also commendable, and most patients did not have abnormal blood indexes.
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| Real shot pictures of GS441524 powder | GS441524 structure diagram |
Product Application
1. GS-441524 99.9% Powder is a small molecule with strong antiviral activity against many RNA viruses.
2. It has low cytotoxicity in a wide range of cell lines.
3. It is the prerequisite molecule for synthesizing nucleotide triphosphate with pharmacological activity.
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