Estradiol valerate powder is a white crystalline powder; Odorless. It is soluble in ethanol, acetone, or chloroform, soluble in methanol, slightly soluble in vegetable oil, and almost insoluble in water.
Density: 1.1±0.1 g/cm3
Boiling point: 486.2±45.0 °C at 760 mmHg
Melting point: 144°C
Molecular formula: C23H32O3
Molecular weight: 356.498
Flash Point: 191.1±21.5 °C
Accuracy: 356.235138
PSA：46.53000
LogP：6.62
Vapor pressure: 0.0±1.3 mmHg at 25°C
Refractive index: 1.568
Estradiol valerate is a long-acting estradiol derivative and a component of long-acting contraceptives.
It is the valerate of natural estradiol, which has the pharmacological effect of estrogen, can promote and regulate the normal development of the female genital tract and secondary sexual characteristics, and participate in the regulation of ovarian axis function.
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| Real shot pictures of Estradiol valerate raw powder | Estradiol valerate structure diagram |
What is Estradiol valerate used for?
1. Estradiol valerate powder corrects estrogen deficiency and symptoms caused by estrogen deficiency, such as unstable vasomotor function, urogenital atrophy, neuropsychiatric symptoms, etc. in women with natural or artificial menopause.
2. Post-menopausal women maintain bone density to prevent or delay the occurrence of osteoporosis; Protect the cardiovascular system and reduce the risk of atherosclerotic cardiovascular disease.
3. Amenorrhea patients of childbearing age artificially induce menstrual cramps to prevent reproductive tract atrophy.
4. Promote the development of breast, secondary sexual characteristics, and reproductive tract of patients with primary amenorrhea.
5. Advanced prostate cancer.
6. Combined with progestogen drugs, it can inhibit ovulation and can be used as a contraceptive.
7. Used for milk withdrawal.
How does Estradiol Valerate work?
Estradiol Valerate Powder is a kind of estrogen, which is a valerate of long-acting estradiol. Estrogen can promote cells to synthesize DNA, RNA, and various protein in corresponding tissues, and reduce the release of follicle-stimulating hormone (FSH), luteinizing hormone (LH), and luteinizing hormone from the pituitary gland by reducing the release of hypothalamic gonadotropin, thus inhibiting ovulation. Decreased LH secretion in men can reduce testosterone secretion in the testis.
What are the contraindications of Estradiol Valerate?
1. Do not use estrogen during pregnancy. Both systemic and vaginal medication may lead to fetal malformation. The baby girl born after taking medicine may have an abnormal reproductive tract. A case report of vaginal cancer or cervical cancer in women of childbearing age after using this medicine.
2. Estrogen can enter the milk through the mammary gland and be discharged and can inhibit lactation, so it is forbidden for lactating women.
3. Known or suspected breast cancer, except when used to treat advanced metastatic breast cancer.
4. Known or suspected to have estrogen-dependent tumors (such as endometrial cancer).
5. Acute thrombophlebitis or thromboembolism.
6. Patients who have been accompanied by thrombophlebitis or thromboembolism before using estrogen, except for the treatment of advanced breast cancer and prostate cancer.
7. There is a history of cholestatic jaundice.
8. Irregular vaginal bleeding without definite diagnosis.
How to choose more products
Estradiol | 50-28-2 |
Allylestrenol | 432-60-0 |
Ethynyl estradiol | 57-63-6 |
Estriol | 50-27-1 |
Estradiol Benzoate | 50-50-0 |
Estradiol Enanthate/ | 4956-37-0 |
Estradiol valerate | 979-32-8 |
Estradiol cypionate/Depofemin | 313-06-4 |
Progesterone | 57-83-0 |
Ipriflavone | 35212-22-7 |
17alpha-Ethynyl-19-nortestosterone 17-heptanoate | 3836-23-5 |
19-Norethindrone acetate | 51-98-9 |
Levonorgestrel | 797-63-7 |
Androsta-1,4-diene-3,17-dione/Androstadiendione | 897-06-3 |
dydrogesterone | 152-62-5 |
Algestone Acetophenide | 24356-94-3 |
Megestrol acetate | 595-33-5 |
norethisterone | 68-22-4 |
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Transportation Time | Shipping method | Cargo weight requirements | Advantage |
3-7 days | DHL,Germany DHL,Germany DPD, | Suitable for under 50kg. | We have warehouses in Germany and California, USA, |
7-15 days | By Air | Suitable for more than 50kg. | |
15-60 days | By Sea | Suitable for more than 500kg. |
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Note: This compound should be used for research purposes only. These claims have not been evaluated by the Food and Drug Administration. Please consult your doctor and learn about available studies before using them. This product is not intended to diagnose, treat, cure or prevent any disease.
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