what is phlorizin weight loss?
Phlorizin weight loss is a glucoside of phloretin, a dihydrochalcone. Samples often appear yellowing to impurities. It is of sweet taste and contains four molecules of water in the crystal. Upon prolonged exposure to aqueous solutions phlorizin hydrolyzes to phloretin and glucose.
 |
Product name |
phlorizin |
|
CAS |
60-81-1 |
|
|
Molecular formula |
C21H24O10 | |
|
Molecular weight |
436.41 | |
| EINECS | 200-487-1 | |
|
Appearance |
light yellow powder |
|
| Melting point | 113-114 °C(lit.) | |
| Density | 1.3178 (rough estimate) |
In which plants is Phlorizin weight loss distributed?
Phlorizin weight loss is mainly found in plants of the Rosaceae family and the Apple genus.Phlorizin has also been reported in plants of the Asteraceae, Ericaceae, Leguminosae, Fagaceae, and Liliaceae families, but in relatively small amounts. In recent years, the presence of root bark glycosides has also been found in plants such as lychee peels, durian leaves, and Cynomorium songaricum, with relatively low levels. However, Phlorizin is abundant in the sweet tea multi spike family. Overall, apple plants are the main source of Phlorizin and can be utilized as raw materials for extracting Phlorizin. Apple branches, leaves, bark, etc. all contain a large amount of Phlorizin. The distribution of Phlorizin in apple fruit is concentrated on the seeds and peel
What are the uses of Phlorizin weight loss?
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Phlorizin weight loss has been approved as a food additive. Phlorizin can promote the absorption and utilization of genistein, which inhibits the growth and metastasis of tumor cells. It is a natural sweetener with very high sweetness, and can be used as a sugar substitute for diabetics who are sweet lovers. Food processing industry, replacing artificial dyes to avoid the toxic effects of synthetic pigments. Due to its easy hydrolysis in the human body to form Phloretin, and its low absorption rate in the small intestine, Phlorizin weight loss is often designed as a polymer with other compounds for drug development. |
The antioxidant activity and anti-aging function of cosmetics Phlorizin have been confirmed by modern scientific research. Phloretin, the hydrolysis product of Phlorizin weight loss can competitively inhibit tyrosinase activity and interfere with melanin synthesis, resulting in a whitening effect superior to many whitening products on the market.If you need it, pls click e-mail sales1@faithfulbio.com
What are the biological activities of Phlorizin weight loss?
1. Reduce blood sugar levels
Numerous studies have shown that Phlorizin weight loss has the effect of reducing fasting blood glucose, and the mechanism by which Phlorizin lowers blood glucose is the competitive inhibition of the transport of glucose molecules by glucose transporters (SGLTs and GLUTs).
2. Antioxidant activity
It has a significant protective effect against oxidative damage caused by high-fat diet in fruit flies, enhancing SOD and CAT activity, significantly prolonging fruit fly lifespan, and possessing strong antioxidant properties.
3. Physiological correlation with plants
Phlorizin is closely related to physiological phenomena such as plant growth, development, and stress resistance. It can resist various pathogens, such as apple scab, fire disease, etc. However, it can have inhibitory effects on the growth of certain plants.
Product Specification
| Items | Specifications |
Result |
|
Appearance |
light yellow powder | light yellow powder |
|
Odor |
Characteristic |
Complies |
|
Assay (HPLC) |
≥80% |
85% |
|
Loss on Drying |
≤5% |
3.56% |
|
Residue on Ignition |
≤5% |
2.05% |
|
Heavy Metal |
<10ppm |
Complies |
|
As |
<0.2ppm |
Complies |
|
Pb |
<1.0ppm |
Complies |
|
Total Plate Count |
<1000cfu/g |
Complies |
|
Yeast & Moulds |
<100cfu/g |
Complies |
|
E.Coli |
Negative |
Complies |
|
Salmonella |
Negative |
Complies |
How to Extract Phlorizin weight loss?
(1) Raw material crushing: Crush dried apple branches or leaves into 10-20 mesh or 20-30 mesh coarse powder;
(2) Extraction: Put the crushed coarse powder raw material into a round bottom flask, add 70% solvent A for reflux extraction 3 times, add liquid amounts of 6, 4, and 4 BV each time, each time for 1 hour, and combine the extraction solutions; (Three extraction solutions ranging from brown to brown)
(3) Concentration: Add antioxidant VC to 0.2% of the total weight of the extracted liquid after merging, and distill under reduced pressure at 60 ℃ to recover solvent A; (The concentrated solution appears as a dark brown turbid liquid)
(4) Removal of impurities: Add 0.5% by weight of the concentrated solution that has been recovered to be alcohol free to POLYLUMINIUM CHLORIDE, adjust the pH to 7.5 with Calcium hydroxide, place it in a conical flask, keep it at 60 ℃ for 30 minutes, and filter to obtain a clear solution; (After adding POLYLUMINIM CHLORIDE, there is a flocculent precipitate generated at the bottom of the bottle)
(5) Extraction: Cool the concentrated extraction solution and extract it three times with 1 times the amount of solvent to obtain a solution; (Rapid stratification of solution)
(6) Concentration: Reflux the extract from the previous step under reduced pressure and concentrate it to a ratio of 10:1 to obtain a concentrated solution;
(7) Purification: Dissolve the concentrated solution in 40% solvent A, filter, let the filtrate stand for 24 hours, filter to obtain crystals, and dry the Phlorizin weight loss under normal or reduced pressure. (Yellow powder) decolorize the crude product with activated carbon,
How and where to buy Phlorizin weight loss?
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