Esculin CAS 531-75-9

Esculin CAS 531-75-9

Product Name:Esculin
Synonym:BICOLOIN;ESCULETIN-6-O-GLUCOSIDE;ESCULETIN-6-GLUCOSIDE;ESCULOSIDE;Esculinsesquimonohydrate
CAS NO.:531-75-9
EINECS NO.:208-517-5
Molecular Formula:C15H16O9
Purity & Grade: Different specifications; Medicine grade
Character:White Powder
Free sample:Available
Stock:In stock
Warehouse: USA/EU/AU Warehouse
MOQ & Package: 1g; Package according to demand
Shipping: Safe and fast delivery
Lead Time: 7-15 days
Store & Shelf life: Cool & dry place; 24 months
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Description
 
 

Product description

Esculin

Esculin is a coumarin compound extracted from the dried bark or bark of the Metasequoia glyptostula, a plant of the Oleaceae family. It is an effective component of the traditional Chinese medicine Qinpi. At room temperature, it is a white crystalline powder with a slightly bitter smell. Both Esculin and Esculetin have good therapeutic effects on bacillary dysentery and tracheitis. In addition, Esculin also has anti-inflammatory, antibacterial, anticoagulant and analgesic activities, and has a significant diuretic effect on mice. It can inhibit aldose reductase in the lens of rat eyes, is a growth inhibitor of Bacillus subtilis, and also has an inhibitory effect on chemical carcinogenesis.

Qinpi is a commonly used traditional Chinese medicine, usually derived from the plants Fraxinus rhynchophyllaHanee, Fraxinus chinensis Roxb and Fraxinusszaboana Lingelsh of the Oleaceae family. Or the dried bark or dry bark of the evergreen Fraxinus stylosaLing. According to traditional Chinese medicine theory, Qin PI has the effects of clearing heat, drying dampness, astringency and improving eyesight. It is often used to treat hot dysentery, diarrhea, red and white leucorrhea, red, swollen and painful eyes, and cataracts in the eyes. The main components of Qinpi are coumarins, including Esculin, Esculetin, Fraxetin, etc. Among them, Esculin has the highest content, approximately 1%.

Esculin HTML

 

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COA

 

Items Standard Result
Assay 98% 98.11%
Appearance: Light yellow to off-white powder Complies
Melting point 204-206℃ 205℃
Mesh size: 100%pass 80mesh Complies
Loss on drying: ≤1.0% 0.52%
Residue on ignition: ≤1.0% 0.36%
Heavy metals: ≤20PPM Complies
As: ≤2PPM Complies
Microbiology:
Total Plate Count:
Yeast &Mold:
E.Coli:
S.Aureus:
Salmonella:

<1000cfu/g
<100cfu/g
Negative
Negative
Negative

28cfu/g
5cfu/g
Complies
Complies
Complies
Conclusion Conform with enterprise specification

 

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Esculin MF

Density: 1.7±0.1 g/cm ³
Boiling point: 697.7±55.0 °C at 760 mmHg
Melting point: 203 °C
Molecular formula: C15H16O9
Molecular weight: 340.29
Flash point: 262.8±25.0 °C
PSA 149.82000
LogP -1.52

 

What is Esculin used for?

Esculin is similar to hydroxycoumarin, which is a "blood thinner" (anticoagulant). It has been used to decrease swelling. It may increase the risk of bleeding and may be harmful if swallowed.

 

Is Esculin a sugar?

Esculin belongs to the family of Glycosyl Compounds. These are carbohydrate derivatives in which a sugar group is bonded through its anmoeric carbonA to another group via a C-, S-,N-,O-, or Se- glycosidic bond.

 

What is the Esculin test for bacteria?

The bile-esculin test is widely used to differentiate enterococci and group D streptococci, which are bile tolerant and can hydrolyze esculin to esculetin, from non-group D viridans group streptococci, which grow poorly on bile.

 

The preparation method of high-purity Esculin

 

At present, the preparation of Esculin adopts the 95% ethanol reflux extraction method, which includes concentrating the extract until it has no alcohol taste and then extracting it with ethyl acetate to remove Esculetin. The obtained solution is then concentrated to precipitate Esculin crystals. In this method, 95% ethanol and ethyl acetate are used, which is costly. Moreover, the extraction process is prone to emulsification and the operation is rather troublesome. Moreover, there are significant difficulties in the concentration step because when the solution volume is too small, the viscosity is too high, making it very difficult to precipitate crystals. In addition, the obtained Esculin crystals contain a large amount of Fraxetin, and the purity is not ideal.
In addition, in the existing methods for extracting Esculin, ethyl acetate is usually used for extraction. If the operators are exposed to ethyl acetate for a long time during the work process, it will cause harm to the human body, such as liver damage, and also cause certain pollution to the environment.

 

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With our continuous efforts and good service, we sincerely hope to establish long-term cooperation and common development with customers and give us a chance. We believe that we will satisfy you with first-class quality, safe and fast delivery and enthusiastic after-sales service.

 

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Package

 

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Shipping Methods

 

Transportation Time

Shipping method

Cargo weight requirements

Advantage

3-7 days

DHL,Germany DHL,Germany DPD,
UPS,USPS,FedEx,TNT,EMS

Suitable for under 50kg.
International door to door express

We have warehouses in Germany and California, USA, and customers in Europe and America can enjoy sending goods directly from these two places.

7-15 days

By Air

Suitable for more than 50kg.
fast and cheaper for large order

15-60 days

By Sea

Suitable for more than 500kg.
Cheapest shipping way

 

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Disclaimer: All conventional products (non-customized products) pictures are taken in kind, but due to the influence of light (different time, different background light), shooting method, different display equipment parameters and other factors, there may be some differences between the picture and the real color, product color, please take the real effect prevail, product color difference is not a product quality problem.
 
Note: Always consult a qualified health practitioner before taking any new medication. This product is not intended to diagnose, treat, cure or prevent any disease.At the time of purchase, the international buyer agrees to assume the risk of all items arriving. We cannot replace lost or impounded items. Before sending items, you need to confirm that you agree to these terms.This is only a recommended dose based on our own experience and anecdotal evidence. We recommend that you do your own research before using this product.
 
Statement: This product is only used for scientific research, and the consequences of other uses are not responsible.

 

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