H-Gly-Pro-Hyp-OH Raw Powder CAS 2239-67-0

Collagen tripeptide is a synthetic tripeptide composed of glycine (Gly), proline (Pro), and hydroxyproline (Hyp), with a molecular formula of C12H19N3O5, a molecular weight of 285.3, and a CAS number of 2239-67-0. It is the most abundant triple helix structure in collagen,The abbreviation of molecular structure is H-GLY-PRO-HYP-OH Raw Powder accounting for 57% of the total amino acids in collagen, and is a precursor substance for collagen synthesis.

What are the benefits of H-Gly-Pro-Hyp-OH Raw Powder?

1. Promote collagen synthesis: As a precursor to collagen synthesis, Collagen Tripeptide Raw Powder can significantly promote fibroblast proliferation and collagen synthesis. Clinical studies have shown that adding an appropriate amount of H-GLY-PRO-HYP-OH Raw material to cosmetics increases skin moisture content by 23%, skin elasticity by 93%, and skin smoothness by 62%.
2. Anti photoaging effect: In the UV induced photoaging model, it can increase the content of hyaluronic acid and collagen, improve skin elasticity and epidermal thickness, reduce the content of matrix metalloproteinases (MMP-1, MMP-3), and prevent collagen degradation.
3. Improve skin barrier: Studies have shown that moderate amounts of active Tripeptide-29 powder can enhance skin barrier function, reduce transdermal water loss, and improve skin moisturizing ability.

What is the safety and skin absorption capacity of H-GLY-PRO-HYP-OH Raw Powder?

Tripeptide-29 has high safety, small molecular weight, simple structure, and reduces the risk of antigen antibody reactions and allergies, making it suitable for long-term use. According to relevant research statistics, compared to growth factor peptides, it has higher safety and there is no need to worry about proliferation or tumor risks. And it can be used through a safe and convenient external coating method during the usage process. We know that collagen hydrolysate containing Gly-Pro-Xaa tripeptide can significantly enhance the absorption of Pro-Hyp, Hyp-Gly, and Gly-Pro-Hyp into the body. Studies have shown that the area under the concentration time curve (AUC) values of H-GLY-PRO-HYP-OH raw powder are increased by 1.77 times, 2.18 times, and 65.07 times, respectively. Moreover, the Gly-Pro-Hyp active molecule isolated from it maintains its intact form in the blood and can be effectively utilized by skin tissue.

What is the performance of H-GLY-PRO-HYP-OH Raw Powder in the field of skincare?

Tripeptide-29 raw powder is widely used in the field of skin care products, mainly used in anti-aging essence, eye cream, face cream, facial mask and other products. The recommended concentration is 0.1% -1%. Compared to other peptides, tripeptide-29 has a small molecular weight, good transdermal absorption, high safety, and is suitable for long-term use. Based on its detailed information, we summarize as follows:
Promoting collagen synthesis: Tripeptide-29 can stimulate fibroblast proliferation, promote the synthesis of type I and III collagen, and enhance skin elasticity and firmness.
Anti aging effect: By inhibiting the activity of matrix metalloproteinases (MMPs), reducing the degradation of collagen and elastin, and delaying skin aging.
Improving skin barrier: enhancing the hydration of the stratum corneum, improving the skin's moisturizing ability, and reducing transdermal water loss.

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FAQ:

Q1:What are the storage conditions for H-GLY-PRO-HYP-OH raw powder?
H-GLY-PRO-HYP-OH powder can be stored for 3 years at -20 ° C and 2 years at 4 ° C. In solvents, it can be stored for 6 months at -80 ° C and 1 month at -20 ° C. It is insoluble or insoluble in water and ethanol, and it is recommended to use DMSO 4mg/mL (8.86mM) for matching.

Q2:How to prepare H-GLY-PRO-HYP-OH solution?
5mg of H-GLY-PRO-HYP-OH raw powder can be prepared into a 10mM solution by adding 1.11ml of DMSO, or adding 1ml of DMSO every 4.51mg. It is recommended to dilute with physiological saline to the desired concentration before use after successful configuration.

Q3:How is its research and development progress?
H-GLY-PRO-HYP-OH has been widely used in the fields of skincare and health products, and clinical studies have confirmed its safety and effectiveness. Currently, further research is being conducted on its potential applications in fields such as osteoarthritis and osteoporosis.

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